#CotM: we now have #cullin E3 ligases from 6 species (#human, #mouse, @wormbase #arath @yeastgenome @PomBase). Find them all with GO:0031461.
Here's one with its #crystalStructure from @PDBeurope #4a0k:
ebi.ac.uk/complexportal/…
Here's one with its #crystalStructure from @PDBeurope #4a0k:
ebi.ac.uk/complexportal/…
December 3, 2024 at 10:37 AM
#CotM: we now have #cullin E3 ligases from 6 species (#human, #mouse, @wormbase #arath @yeastgenome @PomBase). Find them all with GO:0031461.
Here's one with its #crystalStructure from @PDBeurope #4a0k:
ebi.ac.uk/complexportal/…
Here's one with its #crystalStructure from @PDBeurope #4a0k:
ebi.ac.uk/complexportal/…
Thanks to @ELIXIREurope - funding Brno students visit @emblebi to work with @intact_project and @PDBeurope on curation in #complexportal
December 9, 2024 at 11:47 AM
Thanks to @ELIXIREurope - funding Brno students visit @emblebi to work with @intact_project and @PDBeurope on curation in #complexportal
#CofM: Eukaryotic translation initiation factor 4E-Mxt complex from #celegansGoing to "Ecology, Evolution & Genomics of C. elegans..."? Find Hema at P8 on Friday & discover all things C. elegans in @complexportal & @uniprot
@ACSCevents #worm18
@wormbase
ebi.ac.uk/complexportal/…
@ACSCevents #worm18
@wormbase
ebi.ac.uk/complexportal/…
December 3, 2024 at 10:38 AM
#CofM: Eukaryotic translation initiation factor 4E-Mxt complex from #celegansGoing to "Ecology, Evolution & Genomics of C. elegans..."? Find Hema at P8 on Friday & discover all things C. elegans in @complexportal & @uniprot
@ACSCevents #worm18
@wormbase
ebi.ac.uk/complexportal/…
@ACSCevents #worm18
@wormbase
ebi.ac.uk/complexportal/…
Check out our dog complex or any of our 15 other species we provide #NationalDogDay
ebi.ac.uk/complexportal/… ebi.ac.uk/complexportal/…
ebi.ac.uk/complexportal/… ebi.ac.uk/complexportal/…
Complex Portal
EMBL-EBI
www.ebi.ac.uk
December 3, 2024 at 10:35 AM
Check out our dog complex or any of our 15 other species we provide #NationalDogDay
ebi.ac.uk/complexportal/… ebi.ac.uk/complexportal/…
ebi.ac.uk/complexportal/… ebi.ac.uk/complexportal/…
#ProTip: 'shift + left mouse click' lets you zoom into the sequence! #complexviewer #complexportal Give it a try:
ebi.ac.uk/complexportal/…
ebi.ac.uk/complexportal/…
Complex Portal
EMBL-EBI
www.ebi.ac.uk
December 3, 2024 at 10:34 AM
#ProTip: 'shift + left mouse click' lets you zoom into the sequence! #complexviewer #complexportal Give it a try:
ebi.ac.uk/complexportal/…
ebi.ac.uk/complexportal/…
Join this course if you want to learn more about proteins from querying functions in @uniprot to structures in @PDBeurope while exploring molecular interactions in @intact_project or molecular complexes in @complexportal on the way.
x.com/EBItraining/st…
x.com/EBItraining/st…
December 9, 2024 at 11:52 AM
Join this course if you want to learn more about proteins from querying functions in @uniprot to structures in @PDBeurope while exploring molecular interactions in @intact_project or molecular complexes in @complexportal on the way.
x.com/EBItraining/st…
x.com/EBItraining/st…
Check out IntAct 213 release #FeaturedDataset! Winczura et al. in Cell Reports… on the function of ZC3H18 and its interaction with components of the CBC complex (@complexportal #CotM):
ebi.ac.uk/intact/query/p… europepmc.org/abstract/MED/2…
ebi.ac.uk/intact/query/p… europepmc.org/abstract/MED/2…
Europe PMC
Europe PMC is an archive of life sciences journal literature.
europepmc.org
December 9, 2024 at 11:50 AM
Check out IntAct 213 release #FeaturedDataset! Winczura et al. in Cell Reports… on the function of ZC3H18 and its interaction with components of the CBC complex (@complexportal #CotM):
ebi.ac.uk/intact/query/p… europepmc.org/abstract/MED/2…
ebi.ac.uk/intact/query/p… europepmc.org/abstract/MED/2…
Brave choice by @bmeldal to live demo #complexportal at #biocuration2017 is paying off - heard attendee say the viewer is 'cool'
December 9, 2024 at 11:47 AM
Brave choice by @bmeldal to live demo #complexportal at #biocuration2017 is paying off - heard attendee say the viewer is 'cool'
Want 2 know how we curate biological complexes @emblebi? Check out the @intact_project #complexportal publication at:
nar.oxfordjournals.org/content/early/…
nar.oxfordjournals.org/content/early/…
December 9, 2024 at 11:42 AM
Want 2 know how we curate biological complexes @emblebi? Check out the @intact_project #complexportal publication at:
nar.oxfordjournals.org/content/early/…
nar.oxfordjournals.org/content/early/…
Brave choice by @bmeldal to live demo #complexportal at #biocuration2017 is paying off - heard attendee say the viewer is 'cool'
December 9, 2024 at 11:48 AM
Brave choice by @bmeldal to live demo #complexportal at #biocuration2017 is paying off - heard attendee say the viewer is 'cool'
Files for complex annotations are available atan example of #complexportal annotations is at
ebi.ac.uk/intact/complex… ebi.ac.uk/GOA
ebi.ac.uk/intact/complex… ebi.ac.uk/GOA
December 9, 2024 at 11:42 AM
Files for complex annotations are available atan example of #complexportal annotations is at
ebi.ac.uk/intact/complex… ebi.ac.uk/GOA
ebi.ac.uk/intact/complex… ebi.ac.uk/GOA
Did you know that we cover 18 different organisms? Have a look:🐗🐔🐸🐇🐌🐀🐄🐕 and many more, but unfornetly no 🦄
ebi.ac.uk/complexportal/
ebi.ac.uk/complexportal/
Complex Portal
EMBL-EBI
www.ebi.ac.uk
December 3, 2024 at 10:35 AM
Did you know that we cover 18 different organisms? Have a look:🐗🐔🐸🐇🐌🐀🐄🐕 and many more, but unfornetly no 🦄
ebi.ac.uk/complexportal/
ebi.ac.uk/complexportal/
#CotM: for #FathersDay we give you the Oligosaccharyl transferase complex in C. elegans. It contains #dad1 and transfers #sugar (well, glycans) in the first step of protein N-glycosylation 🍫🍪🍰@PDBeurope has the human structure
ebi.ac.uk/pdbe/entry/pdb… ebi.ac.uk/complexportal/…
ebi.ac.uk/pdbe/entry/pdb… ebi.ac.uk/complexportal/…
December 3, 2024 at 10:41 AM
#CotM: for #FathersDay we give you the Oligosaccharyl transferase complex in C. elegans. It contains #dad1 and transfers #sugar (well, glycans) in the first step of protein N-glycosylation 🍫🍪🍰@PDBeurope has the human structure
ebi.ac.uk/pdbe/entry/pdb… ebi.ac.uk/complexportal/…
ebi.ac.uk/pdbe/entry/pdb… ebi.ac.uk/complexportal/…
Do you have any feature requests or found a problem? We would like to hear your feedback! 😉👍#complexportal
github.com/Complex-Portal…
github.com/Complex-Portal…
December 3, 2024 at 10:34 AM
Do you have any feature requests or found a problem? We would like to hear your feedback! 😉👍#complexportal
github.com/Complex-Portal…
github.com/Complex-Portal…
#CotM: the Membane Attack Complex is the final complex of all 3 #complementPathways of the #innateImmuneSystem. All complexes of the classical, alternative and lectin pathway are now available for #human.Activated by most pathogens 🦠, incl. #SARSCoV2
ebi.ac.uk/complexportal/…
ebi.ac.uk/complexportal/…
December 3, 2024 at 10:41 AM
#CotM: the Membane Attack Complex is the final complex of all 3 #complementPathways of the #innateImmuneSystem. All complexes of the classical, alternative and lectin pathway are now available for #human.Activated by most pathogens 🦠, incl. #SARSCoV2
ebi.ac.uk/complexportal/…
ebi.ac.uk/complexportal/…
#ComplexViewer Updates:
1. Complexes as participants are displayed by default and colour-coded, e.g. #SARSCoV2 Spike-hACE2 complex (CPX-5683 or the 3-tier CMG-Pol epsilon complex (CPX-1556.
1/2
ebi.ac.uk/complexportal/… ebi.ac.uk/complexportal/…
1. Complexes as participants are displayed by default and colour-coded, e.g. #SARSCoV2 Spike-hACE2 complex (CPX-5683 or the 3-tier CMG-Pol epsilon complex (CPX-1556.
1/2
ebi.ac.uk/complexportal/… ebi.ac.uk/complexportal/…
December 3, 2024 at 10:40 AM
#ComplexViewer Updates:
1. Complexes as participants are displayed by default and colour-coded, e.g. #SARSCoV2 Spike-hACE2 complex (CPX-5683 or the 3-tier CMG-Pol epsilon complex (CPX-1556.
1/2
ebi.ac.uk/complexportal/… ebi.ac.uk/complexportal/…
1. Complexes as participants are displayed by default and colour-coded, e.g. #SARSCoV2 Spike-hACE2 complex (CPX-5683 or the 3-tier CMG-Pol epsilon complex (CPX-1556.
1/2
ebi.ac.uk/complexportal/… ebi.ac.uk/complexportal/…
Livia from @intact_project and @complexportal discussing complex representation at #MoCaInRome.
December 3, 2024 at 10:36 AM
Livia from @intact_project and @complexportal discussing complex representation at #MoCaInRome.
#CotM: #ecoli Cobalamin (vitamin B12) transport complex:Find other "active transmembrane transporter activity complexes" by searching the Complex Portal with GO:0022804.
Here is the crystal structure for #2qi9 @PDBeurope:
ebi.ac.uk/complexportal/…
Here is the crystal structure for #2qi9 @PDBeurope:
ebi.ac.uk/complexportal/…
December 3, 2024 at 10:37 AM
#CotM: #ecoli Cobalamin (vitamin B12) transport complex:Find other "active transmembrane transporter activity complexes" by searching the Complex Portal with GO:0022804.
Here is the crystal structure for #2qi9 @PDBeurope:
ebi.ac.uk/complexportal/…
Here is the crystal structure for #2qi9 @PDBeurope:
ebi.ac.uk/complexportal/…
V1 of #complexviewer has been released atimplemented in #complexportal, eg@intermineorg
ebi.ac.uk/intact/complex… npmjs.com/package/comple…
ebi.ac.uk/intact/complex… npmjs.com/package/comple…
npm: complexviewer
A network visualisation that displays molecular interaction data, including detailed residue-level information such as binding sites. Used in EBI's Complex Portal and elsewhere.. Latest version: 2.2.4, last published: 4 months ago. Start using complexviewer in your project by running `npm i complexviewer`. There are no other projects in the npm registry using complexviewer.
www.npmjs.com
December 9, 2024 at 11:46 AM
V1 of #complexviewer has been released atimplemented in #complexportal, eg@intermineorg
ebi.ac.uk/intact/complex… npmjs.com/package/comple…
ebi.ac.uk/intact/complex… npmjs.com/package/comple…
2 weeks left to apply for Database Curator post for @intact_project & @complexportal #biocuration #datacuration
embl.de/jobs/searchjob…
embl.de/jobs/searchjob…
Heidelberg
EMBL's administrative headquarters in the Southern German city of Heidelberg hosts five research units and many of the laboratory's core facilities.
www.embl.de
December 9, 2024 at 11:48 AM
2 weeks left to apply for Database Curator post for @intact_project & @complexportal #biocuration #datacuration
embl.de/jobs/searchjob…
embl.de/jobs/searchjob…
#CotM is the #celegans Fem Ca(2+)/Calmodulin-dependent protein phosphatase complex, involved in male sexual development by
promoting the degradation of tra-1, a transcriptional repressor of male-specific genes.Thank you @uniprot for the curation
ebi.ac.uk/complexportal/…
promoting the degradation of tra-1, a transcriptional repressor of male-specific genes.Thank you @uniprot for the curation
ebi.ac.uk/complexportal/…
December 3, 2024 at 10:37 AM
#CotM is the #celegans Fem Ca(2+)/Calmodulin-dependent protein phosphatase complex, involved in male sexual development by
promoting the degradation of tra-1, a transcriptional repressor of male-specific genes.Thank you @uniprot for the curation
ebi.ac.uk/complexportal/…
promoting the degradation of tra-1, a transcriptional repressor of male-specific genes.Thank you @uniprot for the curation
ebi.ac.uk/complexportal/…
We now provide over 2500 complexes from 20 species! This month's main contributions comes from Livia who curate the #CotM caspase family (GO:0008303) and related apoptosome and Caspase-2 PIDDosome:e.g. human caspase-7: PDB #2ql5
ebi.ac.uk/complexportal/…
ebi.ac.uk/complexportal/…
December 3, 2024 at 10:38 AM
We now provide over 2500 complexes from 20 species! This month's main contributions comes from Livia who curate the #CotM caspase family (GO:0008303) and related apoptosome and Caspase-2 PIDDosome:e.g. human caspase-7: PDB #2ql5
ebi.ac.uk/complexportal/…
ebi.ac.uk/complexportal/…