Yuri Milaneschi
@ymilaneschi.bsky.social
Clinical psychologist, psychotherapist and Associate Professor in Psychiatry & Epidemiology @ Amsterdam UMC. Exploring the biological underpinnings of Depression & Anxiety and how to improve their treatment.
Reposted by Yuri Milaneschi
It is known that #depression is linked to increased incidence of metabolic diseases; now, scientists led by @ymilaneschi.bsky.social from 🇳🇱 @amsterdamumc.bsky.social discovered that different types of depression are linked to different cardiometabolic diseases.
Depression subtypes linked to different cardiometabolic diseases
New insights suggest that treatment should be tailored according to type of depression
healthcare-in-europe.com
October 15, 2025 at 10:29 AM
It is known that #depression is linked to increased incidence of metabolic diseases; now, scientists led by @ymilaneschi.bsky.social from 🇳🇱 @amsterdamumc.bsky.social discovered that different types of depression are linked to different cardiometabolic diseases.
And now, a more comprehensive #openaccess edited volume 📚 on #Metabolic #Neuropsychiatry is available, capturing the collective work and reflections from the Ernst Strüngmann Forum.
link.springer.com/book/10.1007...
link.springer.com/book/10.1007...
October 8, 2025 at 1:29 PM
And now, a more comprehensive #openaccess edited volume 📚 on #Metabolic #Neuropsychiatry is available, capturing the collective work and reflections from the Ernst Strüngmann Forum.
link.springer.com/book/10.1007...
link.springer.com/book/10.1007...
Reposted by Yuri Milaneschi
📣 #PNIRS2026: Save the Date‼️
🗓️ June 22–25, 2026
📍 New Orleans, Louisiana 🇺🇸
✨ Whether your PsychoNeuroImmunology research emphasizes the P, N, or I — we look forward to seeing your work and connecting in The Big Easy!
📻 Stay tuned for more info re: call for abstracts. Please spread the word 🙏🏼
🗓️ June 22–25, 2026
📍 New Orleans, Louisiana 🇺🇸
✨ Whether your PsychoNeuroImmunology research emphasizes the P, N, or I — we look forward to seeing your work and connecting in The Big Easy!
📻 Stay tuned for more info re: call for abstracts. Please spread the word 🙏🏼
October 6, 2025 at 10:45 PM
📣 #PNIRS2026: Save the Date‼️
🗓️ June 22–25, 2026
📍 New Orleans, Louisiana 🇺🇸
✨ Whether your PsychoNeuroImmunology research emphasizes the P, N, or I — we look forward to seeing your work and connecting in The Big Easy!
📻 Stay tuned for more info re: call for abstracts. Please spread the word 🙏🏼
🗓️ June 22–25, 2026
📍 New Orleans, Louisiana 🇺🇸
✨ Whether your PsychoNeuroImmunology research emphasizes the P, N, or I — we look forward to seeing your work and connecting in The Big Easy!
📻 Stay tuned for more info re: call for abstracts. Please spread the word 🙏🏼
Our study in @JAMAPsych ja.ma/4lVx1eu Using 🧬 we found that disruptions in #energy pathways link to specific #MDD symptoms (⬆️ appetite & sleep). This suggests a #depression profile linked to #metabolic risk, opening doors to targeted treatments. #metabolicpsychiatry
Energy Homeostasis in Depression Pathophysiology and Heterogeneity
This study examines whether the genetic liability of metabolic, interoceptive, and motivational pathways involved in energy homeostasis regulation is associated with specific symptoms of major depress...
ja.ma
August 10, 2025 at 2:19 PM
Our study in @JAMAPsych ja.ma/4lVx1eu Using 🧬 we found that disruptions in #energy pathways link to specific #MDD symptoms (⬆️ appetite & sleep). This suggests a #depression profile linked to #metabolic risk, opening doors to targeted treatments. #metabolicpsychiatry
🚨 Preprint Alert 🚨
"Major depression and atherosclerotic disease: linking shared genetics to pathways in blood, brain, heart, and atherosclerotic plaques. " 🧠🫀🩸 The title says it all. Great collaboration with @swvanderlaan.bsky.social . 📄 Read it here: bit.ly/4eTM8T2
"Major depression and atherosclerotic disease: linking shared genetics to pathways in blood, brain, heart, and atherosclerotic plaques. " 🧠🫀🩸 The title says it all. Great collaboration with @swvanderlaan.bsky.social . 📄 Read it here: bit.ly/4eTM8T2
Major depression and atherosclerotic disease: Linking shared genetics to pathways in blood, brain, heart, and atherosclerotic plaques
Background The increased risk of atherosclerotic diseases (stroke, coronary artery disease [CAD]) observed in depression may stem from shared pathophysiology. We examined whether: 1) major depression ...
bit.ly
July 15, 2025 at 12:47 PM
🚨 Preprint Alert 🚨
"Major depression and atherosclerotic disease: linking shared genetics to pathways in blood, brain, heart, and atherosclerotic plaques. " 🧠🫀🩸 The title says it all. Great collaboration with @swvanderlaan.bsky.social . 📄 Read it here: bit.ly/4eTM8T2
"Major depression and atherosclerotic disease: linking shared genetics to pathways in blood, brain, heart, and atherosclerotic plaques. " 🧠🫀🩸 The title says it all. Great collaboration with @swvanderlaan.bsky.social . 📄 Read it here: bit.ly/4eTM8T2
In May 2024, I joined an inspiring week at the Ernst Strüngmann Forum on #Metabolic #Neuropsychiatry.
Our first outcome is now in Nature Mental Health:
🧠 A Perspective on energy metabolism in psychiatric disorders
🔗 www.nature.com/articles/s44...
More to come in an upcoming volume—stay tuned!
Our first outcome is now in Nature Mental Health:
🧠 A Perspective on energy metabolism in psychiatric disorders
🔗 www.nature.com/articles/s44...
More to come in an upcoming volume—stay tuned!
Brain and body energy metabolism and potential for treatment of psychiatric disorders - Nature Mental Health
This Perspective highlights the important role of energy metabolism in psychiatric disorders and sets the groundwork for future studies in the emerging field of metabolic psychiatry.
www.nature.com
June 25, 2025 at 7:47 PM
In May 2024, I joined an inspiring week at the Ernst Strüngmann Forum on #Metabolic #Neuropsychiatry.
Our first outcome is now in Nature Mental Health:
🧠 A Perspective on energy metabolism in psychiatric disorders
🔗 www.nature.com/articles/s44...
More to come in an upcoming volume—stay tuned!
Our first outcome is now in Nature Mental Health:
🧠 A Perspective on energy metabolism in psychiatric disorders
🔗 www.nature.com/articles/s44...
More to come in an upcoming volume—stay tuned!
Nice reminder of our #PNIRS2025 symposium. @eimearfoley.bsky.social, Naoise Mac Giollabhui, @dpmoriarity.bsky.social (in cross-Atlantic telepathic connection) and I will wait for you tomorrow morning!
June 10, 2025 at 1:51 PM
Nice reminder of our #PNIRS2025 symposium. @eimearfoley.bsky.social, Naoise Mac Giollabhui, @dpmoriarity.bsky.social (in cross-Atlantic telepathic connection) and I will wait for you tomorrow morning!
Reposted by Yuri Milaneschi
Looking forward to this!
If you're attending #PNIRS2025 be sure to come to our session (Symposia 4) on Wednesday morning and say hello 👋
@ymilaneschi.bsky.social @dpmoriarity.bsky.social @uob-ieu.bsky.social
If you're attending #PNIRS2025 be sure to come to our session (Symposia 4) on Wednesday morning and say hello 👋
@ymilaneschi.bsky.social @dpmoriarity.bsky.social @uob-ieu.bsky.social
📢 Next up in our #PNIRS2025 symposia series announcement:
🔖 Member-Sponsored Symposia 3 & 4
🗓️ Wed, Jun 11 | 8:30–10:00 AM
For details >>> 🧵
Get 👏🏼 Ready 👏🏼 PNIRS.org/meetings
#PNIRS2025 #Highlights #PNI #Psychoneuroimmunology #France #Bordeaux #PNIRS 🇫🇷
🔖 Member-Sponsored Symposia 3 & 4
🗓️ Wed, Jun 11 | 8:30–10:00 AM
For details >>> 🧵
Get 👏🏼 Ready 👏🏼 PNIRS.org/meetings
#PNIRS2025 #Highlights #PNI #Psychoneuroimmunology #France #Bordeaux #PNIRS 🇫🇷
June 9, 2025 at 9:17 AM
Looking forward to this!
If you're attending #PNIRS2025 be sure to come to our session (Symposia 4) on Wednesday morning and say hello 👋
@ymilaneschi.bsky.social @dpmoriarity.bsky.social @uob-ieu.bsky.social
If you're attending #PNIRS2025 be sure to come to our session (Symposia 4) on Wednesday morning and say hello 👋
@ymilaneschi.bsky.social @dpmoriarity.bsky.social @uob-ieu.bsky.social
Looking forward to connecting with colleagues at #PNIRS2025 in Bordeaux 🇫🇷.
Don't miss our symposium "Dissecting Depression Heterogeneity along Immuno-Metabolic Pathways: Triangulating Evidence from Hierarchical-Phenotyping, Experimental and Genomic Methods"
Time & Outline of the symposium ⬇️
Don't miss our symposium "Dissecting Depression Heterogeneity along Immuno-Metabolic Pathways: Triangulating Evidence from Hierarchical-Phenotyping, Experimental and Genomic Methods"
Time & Outline of the symposium ⬇️
📢 Next up in our #PNIRS2025 symposia series announcement:
🔖 Member-Sponsored Symposia 3 & 4
🗓️ Wed, Jun 11 | 8:30–10:00 AM
For details >>> 🧵
Get 👏🏼 Ready 👏🏼 PNIRS.org/meetings
#PNIRS2025 #Highlights #PNI #Psychoneuroimmunology #France #Bordeaux #PNIRS 🇫🇷
🔖 Member-Sponsored Symposia 3 & 4
🗓️ Wed, Jun 11 | 8:30–10:00 AM
For details >>> 🧵
Get 👏🏼 Ready 👏🏼 PNIRS.org/meetings
#PNIRS2025 #Highlights #PNI #Psychoneuroimmunology #France #Bordeaux #PNIRS 🇫🇷
June 1, 2025 at 2:47 PM
Looking forward to connecting with colleagues at #PNIRS2025 in Bordeaux 🇫🇷.
Don't miss our symposium "Dissecting Depression Heterogeneity along Immuno-Metabolic Pathways: Triangulating Evidence from Hierarchical-Phenotyping, Experimental and Genomic Methods"
Time & Outline of the symposium ⬇️
Don't miss our symposium "Dissecting Depression Heterogeneity along Immuno-Metabolic Pathways: Triangulating Evidence from Hierarchical-Phenotyping, Experimental and Genomic Methods"
Time & Outline of the symposium ⬇️
Our new study in Translational Psychiatry showed that acylcarnitines (involved in mitochondrial #energy production) were linked to the presence+severity of #depression. Bioenergetic pathways may open new avenues in psychiatry #MetabolicPsychiatry check the paper ➡️: rdcu.be/eaWoN
Acylcarnitines metabolism in depression: association with diagnostic status, depression severity and symptom profile in the NESDA cohort
Translational Psychiatry - Acylcarnitines metabolism in depression: association with diagnostic status, depression severity and symptom profile in the NESDA cohort
rdcu.be
February 25, 2025 at 10:24 AM
Our new study in Translational Psychiatry showed that acylcarnitines (involved in mitochondrial #energy production) were linked to the presence+severity of #depression. Bioenergetic pathways may open new avenues in psychiatry #MetabolicPsychiatry check the paper ➡️: rdcu.be/eaWoN
Reposted by Yuri Milaneschi
🔬 What is Immuno-metabolic Depression?
"Recognizing immune-metabolic mechanisms could be a relevant treatment target for part of the depressed population opens the doors to personalised psychiatry.”
Read more: 🔗 https://buff.ly/3WRwYpK
#MentalHealthResearch #DepressionResearch
"Recognizing immune-metabolic mechanisms could be a relevant treatment target for part of the depressed population opens the doors to personalised psychiatry.”
Read more: 🔗 https://buff.ly/3WRwYpK
#MentalHealthResearch #DepressionResearch
Understanding immuno-metabolic depression | Mental health platform
Researchers from ImmunoMIND recently published a review of the research about a form of depression called immuno-metabolic depression.
buff.ly
February 17, 2025 at 9:00 AM
🔬 What is Immuno-metabolic Depression?
"Recognizing immune-metabolic mechanisms could be a relevant treatment target for part of the depressed population opens the doors to personalised psychiatry.”
Read more: 🔗 https://buff.ly/3WRwYpK
#MentalHealthResearch #DepressionResearch
"Recognizing immune-metabolic mechanisms could be a relevant treatment target for part of the depressed population opens the doors to personalised psychiatry.”
Read more: 🔗 https://buff.ly/3WRwYpK
#MentalHealthResearch #DepressionResearch
Countdown on for the annual @pnirs.bsky.social meeting in Bordeaux #PNIRS2025 . Very excited for our member sponsored symposium (June 11) with @eimearfoley.bsky.social and @dpmoriarity.bsky.social on #depression heterogeneity and #immunometabolic mechanisms See you in 🇫🇷
February 15, 2025 at 11:58 AM
Countdown on for the annual @pnirs.bsky.social meeting in Bordeaux #PNIRS2025 . Very excited for our member sponsored symposium (June 11) with @eimearfoley.bsky.social and @dpmoriarity.bsky.social on #depression heterogeneity and #immunometabolic mechanisms See you in 🇫🇷
New collaboration published in @brainbehavimm.bsky.social Analyses leveraging #genetic data highlighted the potential role of #metabolic alterations (e.g., dyslipidemia, dysglycemia) as mechanisms connecting #childhood maltreatment with psychiatric + somatic #multimorbidity. doi.org/10.1016/j.bb...
February 11, 2025 at 1:32 PM
New collaboration published in @brainbehavimm.bsky.social Analyses leveraging #genetic data highlighted the potential role of #metabolic alterations (e.g., dyslipidemia, dysglycemia) as mechanisms connecting #childhood maltreatment with psychiatric + somatic #multimorbidity. doi.org/10.1016/j.bb...
Reposted by Yuri Milaneschi
1/n Our multi-ancestry #GWAS meta-analysis of major depression is now published in @cellpress.bsky.social.
www.cell.com/cell/fulltex...
A thread 🧵:
www.cell.com/cell/fulltex...
A thread 🧵:
January 14, 2025 at 5:31 PM
1/n Our multi-ancestry #GWAS meta-analysis of major depression is now published in @cellpress.bsky.social.
www.cell.com/cell/fulltex...
A thread 🧵:
www.cell.com/cell/fulltex...
A thread 🧵:
"Immuno-metabolic #depression: from concept to implementation". Our new collaborative review is out in THE LANCET Regional Health - Europe. We reflected on the current standing of the immuno-metabolic depression concept and its potential value for clinical implementation bit.ly/4iAlVdL #openaccess
Immuno-metabolic depression: from concept to implementation
Major depressive disorder is a common, disabling mental disorder characterized by extensive etiological and phenotypic heterogeneity. This heterogenei…
bit.ly
December 18, 2024 at 2:23 PM
"Immuno-metabolic #depression: from concept to implementation". Our new collaborative review is out in THE LANCET Regional Health - Europe. We reflected on the current standing of the immuno-metabolic depression concept and its potential value for clinical implementation bit.ly/4iAlVdL #openaccess
It was a pleasure to contribute to @thementalelf.bsky.social. In my piece, I discuss findings from a recent study by Spiller et al. (JAMA Psychiatry) on the heterogeneity of symptom presentation in mental disorder diagnoses.
The many faces of mental disorders https://buff.ly/3ZlOTVJ
Yuri Milaneschi @ymilaneschi.bsky.social finds that although there are many different faces of mental health problems, some of these faces are far more common than others.
#MentalHealth #Diagnosis #Symptoms #Depression #PTSD #Anxiety
Yuri Milaneschi @ymilaneschi.bsky.social finds that although there are many different faces of mental health problems, some of these faces are far more common than others.
#MentalHealth #Diagnosis #Symptoms #Depression #PTSD #Anxiety
December 6, 2024 at 8:15 AM
It was a pleasure to contribute to @thementalelf.bsky.social. In my piece, I discuss findings from a recent study by Spiller et al. (JAMA Psychiatry) on the heterogeneity of symptom presentation in mental disorder diagnoses.