xyxxy.bsky.social
@xyxxy.bsky.social
Refugee from musky ol' Twitter.
...Existing scripts have recently been updated to reflect current recommended best practices in doing mxGREML analyses, which are described in the README file. (n+2)/n
June 6, 2025 at 8:34 PM
Here is a git repository of R scripts that demonstrate the use of OpenMx's GREML feature: github.com/RMKirkpatric... . It already has some scripts that demonstrate the new GREML capabilities in this OpenMx release, and more such scripts will be coming soon... (n+1)/n
GitHub - RMKirkpatrick/mxGREMLdemos
Contribute to RMKirkpatrick/mxGREMLdemos development by creating an account on GitHub.
github.com
June 6, 2025 at 8:33 PM
Again, read the full announcement of new features, bug-fixes, known issues, GREML-related details, and NPSOL availability here: openmx.ssri.psu.edu/node/4942 n/n
OpenMx 2.22 released! | OpenMx
openmx.ssri.psu.edu
June 6, 2025 at 8:12 PM
The big non-GREML news is that OpenMx can now automatically compute analytic first & second derivatives of the ML fitfunction for some RAM models. We recommend enabling these derivatives for models that have a large number of manifest variables and free parameters. 6/n
June 6, 2025 at 8:12 PM
Other GREML news includes partial support for use of `mxCheckIdentification()` and `mxAutoStart()` with a GREML expectation; see under "Known Issues" for details. 5/n
June 6, 2025 at 8:11 PM
Thus, the following are now possible in an mxGREML model: regressions ("one-headed paths") or nonrecursive paths ("feedback loops") between endogenous phenotypes; accommodating heteroskedasticity; regressing out covariates via a nonlinear or non-identity-link function! 4/n
June 6, 2025 at 8:11 PM
...you can model the mean "explicitly", by naming an arbitrary vector-valued MxMatrix or MxAlgebra to be the phenotypic mean vector (similar to the MxExpectationNormal case)! 3/n
June 6, 2025 at 8:11 PM
First, you don't have to use REML to fit a "GREML" model anymore--you can fit it by ordinary ML instead, with argument `REML=FALSE`! Second, if you're using ordinary ML, instead of modeling the phenotypic mean "implicitly" by naming exogenous covariates... 2/n
June 6, 2025 at 8:11 PM
I think the most exciting new feature is that `mxCheckIdentification()` is now compatible with definition variables! 4/5
December 10, 2024 at 1:56 AM
Of course, non-NPSOL builds of the new version, including for macOS, are available the usual way from CRAN. 3/5
December 10, 2024 at 1:55 AM
As usual, we provide our own NPSOL-enabled builds of the new version for x86_64 Windows and x86_64 Linux/GNU. However, our own builds for macOS are not yet available, and v2.21.8 was the last version to support 32-bit (x86) Windows. 2/5
December 10, 2024 at 1:54 AM