Sebastian Wrighton
LightNews LightNews
banner
wrighton.bsky.social
Sebastian Wrighton
@wrighton.bsky.social
720 followers 610 following 8 posts
MD/PhD training to become a clinical immunologist at the Medical University of Vienna | Passionate about petri dishes, plasma cells, and pastries | he/him
Posts Replies Media Videos
Reposted by Sebastian Wrighton
lydialynch.bsky.social
This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
www.nature.com/articles/s42...
The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism
This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.
www.nature.com
July 28, 2025 at 3:02 PM
Reposted by Sebastian Wrighton
jacquelyngill.bsky.social
This is an absolute disaster. If we don't stop this, they will turn NSF into a pawn of the Trump administration. There will be no research on climate, biodiversity, or anything that isn't eugenics or AI or how to more efficiently destroy the planet for profit.

This cannot be allowed to happen.
Exclusive: NSF faces radical shake-up as officials abolish its 37 divisions
Changes seen as a response to presidential directives on what research to fund
www.science.org
May 9, 2025 at 3:42 AM
Reposted by Sebastian Wrighton
rodrahimi.bsky.social
Very nice paper by Jamie Orengo and colleagues defining the unique features of IgE plasma cells in mice and humans with allergic disease. #ImmunoSky 🧪
IgE plasma cells are transcriptionally and functionally distinct from other isotypes
IgE plasma cells are unique.
www.science.org
March 5, 2025 at 1:55 AM
Reposted by Sebastian Wrighton
possuhuanglab.bsky.social
1/ In two back-to-back papers, we present our de novo TRACeR platform for targeting MHC-I and MHC-II antigens

TRACeR for MHC-I: go.nature.com/4gcLzn5
TRACeR for MHC-II: go.nature.com/4gj5OQk
December 17, 2024 at 12:56 AM
Reposted by Sebastian Wrighton
mfgrp.bsky.social
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
December 11, 2024 at 4:29 PM
Reposted by Sebastian Wrighton
precisionvaxlab.bsky.social

A paper of Firsts for me: rdcu.be/d2gBV
- 1st #StrepA paper
- 1st for my lab (started in 2023).
- 1st senior authorship

📣 Shout out to my amazing co-1st authors @joshosowicki.bsky.social & Hannah Frost.
📣 Andrew Steer & Nikki Moreland for leading this work with me + all other co-authors not on 🦋
Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections
Nature Communications - Streptococcus pyogenes is a deadly bacteria without a vaccine. Here, researchers measured antibodies in serum and saliva from a strep throat human challenge trial. Baseline...
rdcu.be
December 3, 2024 at 1:11 PM
Reposted by Sebastian Wrighton
aberlejudith.bsky.social
Diese Woche im Sentinelsystem Österreich noch immer viele Rhinovirusinfektionen
- Rückgang der SARS-CoV2
Nachweise: Positivrate 9%
- Einige Parainfluenzafälle
- Saisonale Coronaviren (NL63)
- 2 Metapneumovirusfälle…
#DINÖ #MonikaRedlberger #ZentrumVirologie #MedUniWien
November 15, 2024 at 5:56 PM
Reposted by Sebastian Wrighton
germusthermophilus.bsky.social
🧪🦠🌍🖥️🧬Great opportunity for a postdoc AND a PhD on functional ecology Ncycle/denitrification/N2Oreduction, in the group of Sara Hallin at the Swedish Agricultural University.

PhD: www.slu.se/en/about-slu...
Postdoc: www.slu.se/en/about-slu...

🧵1/2
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
October 27, 2024 at 8:05 AM
Reposted by Sebastian Wrighton
pbump.com
Why did Trump claim Harris’s crowd was AI? Why did his team claim that the Times was fudging her lead in swing states?

Because, just as in 2020, he’s planting seeds to claim that Harris’s support is fake and the election was stolen. www.washingtonpost.com/politics/202...
Column | ‘AI’ crowds and unskewed polls: Trump prepares to reject another loss
The former president’s recent rejection of obvious realities indicates that he is not planning to treat a negative 2024 outcome as legitimate.
www.washingtonpost.com
August 13, 2024 at 2:59 AM
Reposted by Sebastian Wrighton
gpollara.bsky.social
What we're aiming for in a Shigella vaccine: O-specific polysaccharide (OSP)-specific functional IgA responses #immunosky #IDsky

www.thelancet.com/journals/lan...
Determinants of immune responses predictive of protection against shigellosis in an endemic zone: a systems analysis of antibody profiles and function
Our findings suggest that OSP-specific functional IgA responses contribute to protective immunity against Shigella infection in a high-burden setting. These findings will assist in the development and...
www.thelancet.com
August 12, 2024 at 7:37 AM
Reposted by Sebastian Wrighton
shengokai.blacksky.app
Come here, y'all.

The idea that one must be "half" something and "half" something else rather than a consummation of both is not just a white supremacist ideal, it's something that is baked into a lot of fundamental philosophy. Like logic.
August 1, 2024 at 8:24 PM
Reposted by Sebastian Wrighton
charlottegarden.bsky.social
A thread on Project 2025 and work law...

1. Project 2025 calls for religious employers to be allowed to discriminate on any basis, including sex or race.
Issue an executive order protecting religious employers and employees. The President should make clear via executive order that religious employers are free to run their businesses according to their religious beliefs, general nondiscrimination laws notwithstanding, and support participation of religious employees and employers as federal contractors and in federal activities and programs. Clarify Title VII’s religious organization exemptions. Congress should clarify Title VII’s religious organization exemptions to make it more explicit that those employers may make employment decisions based on religion regardless of nondiscrimination laws.
July 12, 2024 at 4:57 PM
Reposted by Sebastian Wrighton
sifill.bsky.social
I don’t care that Trump forgot Barron’s age. I don’t care about Trump’s ravings outside the courtroom.

Media outlets covering Trump should prioritize this story. B/c this is about the sale of our country, our planet, & our children’s future to the highest bidder.

www.nytimes.com/2024/05/09/c...
At a Dinner, Trump Assailed Climate Rules and Asked $1 Billion From Big Oil
At a private meeting at Mar-a-Lago, the former president said fossil fuel companies should donate to help him beat President Biden.
www.nytimes.com
May 10, 2024 at 2:50 PM
Reposted by Sebastian Wrighton
older.bsky.social
"no choice" is one of the evergreenest of red flags
nytimes.com The New York Times @nytimes.com · May 1
Columbia University’s president said she had “no choice” but to call in the police after pro-Palestinian protesters occupied a campus building on Tuesday. A total of 109 people were arrested in what was, to many students and faculty, part of a disturbing 24 hours.
Columbia Said It Had ‘No Choice’ but to Call the Police
Columbia’s president expressed regret about calling in the police to clear a previous protest. On Tuesday, she said she had “no choice” after protesters occupied a building on campus.
www.nytimes.com
May 1, 2024 at 5:10 PM
Reposted by Sebastian Wrighton
ruemcclammyhand.bsky.social
imagine being in the nypd and putting on all your fancy little riot gears and getting armed to the teeth to go intimidate a 20 year old kid for saying we should stop a genocide
May 1, 2024 at 4:07 AM
Reposted by Sebastian Wrighton
michaelhobbes.bsky.social
if a computer told you how fucking stupid this is would you believe it
twitter.com/emollick/sta...
April 21, 2024 at 2:03 AM
Reposted by Sebastian Wrighton
robinince.bsky.social
I keep hearing that JK Rowling has paid a huge price for her trans comments but it seems that people are totally unaware of the vicious attacks that trans supporting cis women in entertainment have experienced - and all far far less wealthy - only one side of persecution seems to be of interest
April 17, 2024 at 8:44 PM
Reposted by Sebastian Wrighton
cyrilpedia.bsky.social
"Negative regulation of ILC2s within the skin in response to androgens could thus restrict the number and activation status of dendritic cells in the skin of male mice, contributing to differences in local immune responses between the sexes."
#Immunology
www.science.org/doi/10.1126/...
Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis
Males and females exhibit profound differences in immune responses and disease susceptibility. However, the factors responsible for sex differences in tissue immunity remain poorly understood. Here, w...
www.science.org
April 12, 2024 at 1:37 PM
Reposted by Sebastian Wrighton
rosemarymosco.com
Camera.
Support me on Patreon: www.patreon.com/birdandmoon
A comic with two panels. In panel 1, labeled "when you remember to bring your camera," there's a quiet scene looking across a marsh, with a single osprey on a branch, largely obscured by branches. In panel 2, labeled "when you forget to bring your camera," the marsh scene is full of critters, including a whooping crane, vermilion flycatcher, American flamingo, Atlantic puffin, painted bunting, resplendent quetzal, Steller's sea eagle, two moose, king eider, Kirtland's warbler, Brewster's warbler, a few rare butterflies, flocks of flying birds, many beautiful flowers, and the osprey now unobstructed by twigs.
April 2, 2024 at 1:18 PM
Reposted by Sebastian Wrighton
joolia.bsky.social
“This is not a normal war. The war in Ukraine has killed 500 kids in two years and the war in Gaza has killed over 10,000 in less than five months. We have seen wars before but this is something that is a dark stain on our shared humanity.”
‘Not a normal war’: doctors say children have been targeted by Israeli snipers in Gaza
IDF says it ‘completely rejects’ charge that its soldiers deliberately fired on any of the thousands of civilians killed in Israeli offensive
www.theguardian.com
April 2, 2024 at 1:30 PM
Reposted by Sebastian Wrighton
alexvont.bsky.social
Wholly in agreement with this. I particularly wish people would stop spouting apathetic doomer nonsense like “whether you like it or not, it’s here to stay” or “you can’t stop it.” We do have choices. We can have agency over technology. You don’t need to go passive just because these jerks are rich
bookspotlight.bsky.social Indie Book Spotlight @bookspotlight.bsky.social · Mar 30
can people stop telling me to let ai in the arts go??? if we shut up now, there's no controlling it, no regulating it, artists and authors will keep having all their works cannibalised and reshaped for profit they don't see.

so, no. i won't shut up.

fuck ai.
April 1, 2024 at 11:32 AM