Willi
@willigo09.bsky.social
Working on #SelfDrivingLabs at the Acceleration Consortium @ UofT. Former employee at dsm-firmenich working on self-driving labs for food applications. Interested in systems biology, microbial communities, ML/AI, software development, product management.
Pinned
Willi
@willigo09.bsky.social
· Nov 11
I created a #StarterPack for #SelfDrivingLabs. Please comment if you would like to be added: go.bsky.app/Jq7EKC2
Looking forward to the discussions!
Looking forward to the discussions!
Reposted by Willi
modern-sql.com now covers DuckDB.
Modern SQL: A lot has changed since SQL-92
SQL has evolved. Beyond the relational model. Discover it now.
modern-sql.com
November 28, 2025 at 1:24 PM
modern-sql.com now covers DuckDB.
Reposted by Willi
The 2025 Accelerate Conference was our biggest yet! We welcomed 435 attendees from nearly 20 countries to
@marsdd.bsky.social & @torontosri.bsky.social on the @utoronto.ca campus.
Take a look back: acceleration.utoronto.ca/news/acceler...
@marsdd.bsky.social & @torontosri.bsky.social on the @utoronto.ca campus.
Take a look back: acceleration.utoronto.ca/news/acceler...
November 28, 2025 at 4:47 PM
The 2025 Accelerate Conference was our biggest yet! We welcomed 435 attendees from nearly 20 countries to
@marsdd.bsky.social & @torontosri.bsky.social on the @utoronto.ca campus.
Take a look back: acceleration.utoronto.ca/news/acceler...
@marsdd.bsky.social & @torontosri.bsky.social on the @utoronto.ca campus.
Take a look back: acceleration.utoronto.ca/news/acceler...
Reposted by Willi
Coming soon to Chemical Science:
SynTwins: A Retrosynthesis-Guided Framework for Synthesizable Molecular Analog Generation
📜 arxiv.org/abs/2507.02752
By Shuan Chen, Gunwook Nam, @aspuru.bsky.social, and Yousung Jung.
[1/5]
SynTwins: A Retrosynthesis-Guided Framework for Synthesizable Molecular Analog Generation
📜 arxiv.org/abs/2507.02752
By Shuan Chen, Gunwook Nam, @aspuru.bsky.social, and Yousung Jung.
[1/5]
November 28, 2025 at 7:07 PM
Coming soon to Chemical Science:
SynTwins: A Retrosynthesis-Guided Framework for Synthesizable Molecular Analog Generation
📜 arxiv.org/abs/2507.02752
By Shuan Chen, Gunwook Nam, @aspuru.bsky.social, and Yousung Jung.
[1/5]
SynTwins: A Retrosynthesis-Guided Framework for Synthesizable Molecular Analog Generation
📜 arxiv.org/abs/2507.02752
By Shuan Chen, Gunwook Nam, @aspuru.bsky.social, and Yousung Jung.
[1/5]
Reposted by Willi
From the Grammarly community on Reddit
Explore this post and more from the Grammarly community
www.reddit.com
November 28, 2025 at 4:27 PM
Reposted by Willi
The initial lineup of keynotes and spotlight talks is finalised, with 10 contributed talks still up for grabs! Come join us in Bristol on 15-16 Jan 2026 for AI, Engineering Biology and Beyond to shape the future of these fields🤖🧬🦠Register now at: aiebab.github.io
November 20, 2025 at 9:52 AM
The initial lineup of keynotes and spotlight talks is finalised, with 10 contributed talks still up for grabs! Come join us in Bristol on 15-16 Jan 2026 for AI, Engineering Biology and Beyond to shape the future of these fields🤖🧬🦠Register now at: aiebab.github.io
Reposted by Willi
DeepSeek just released a new state of the art math prover, DeepSeek-Math-V2, competitive with Google, OpenAI or ByteDance, while being a publicly documented open weight models. A few reading notes along the way:
November 27, 2025 at 3:41 PM
DeepSeek just released a new state of the art math prover, DeepSeek-Math-V2, competitive with Google, OpenAI or ByteDance, while being a publicly documented open weight models. A few reading notes along the way:
Reposted by Willi
I wrote a “How to” book for conference posters that’s a great present for early career researchers or a lab resource!
If you’d like to give one a a gift with a little something extra, DM me for a bookplate!
pelagicpublishing.com/products/bet...
If you’d like to give one a a gift with a little something extra, DM me for a bookplate!
pelagicpublishing.com/products/bet...
November 27, 2025 at 2:17 PM
I wrote a “How to” book for conference posters that’s a great present for early career researchers or a lab resource!
If you’d like to give one a a gift with a little something extra, DM me for a bookplate!
pelagicpublishing.com/products/bet...
If you’d like to give one a a gift with a little something extra, DM me for a bookplate!
pelagicpublishing.com/products/bet...
Reposted by Willi
An inspirational example of 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐜𝐫𝐞𝐚𝐭𝐢𝐯𝐢𝐭𝐲, 𝐨𝐫𝐢𝐠𝐢𝐧𝐚𝐥𝐢𝐭𝐲 𝐚𝐧𝐝 𝐫𝐢𝐠𝐨𝐫:
Chemiosmosis remains one of the most striking examples of originality in modern biology. At a time when biochemical dogma insisted on high-energy intermediates, Peter Mitchell proposed & rigorously articulated the radical ...
Chemiosmosis remains one of the most striking examples of originality in modern biology. At a time when biochemical dogma insisted on high-energy intermediates, Peter Mitchell proposed & rigorously articulated the radical ...
November 27, 2025 at 1:45 PM
An inspirational example of 𝐬𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐜𝐫𝐞𝐚𝐭𝐢𝐯𝐢𝐭𝐲, 𝐨𝐫𝐢𝐠𝐢𝐧𝐚𝐥𝐢𝐭𝐲 𝐚𝐧𝐝 𝐫𝐢𝐠𝐨𝐫:
Chemiosmosis remains one of the most striking examples of originality in modern biology. At a time when biochemical dogma insisted on high-energy intermediates, Peter Mitchell proposed & rigorously articulated the radical ...
Chemiosmosis remains one of the most striking examples of originality in modern biology. At a time when biochemical dogma insisted on high-energy intermediates, Peter Mitchell proposed & rigorously articulated the radical ...
Reposted by Willi
Reposted by Willi
looking for a 5y postdoc to work with Stephen Dale (scholar.google.com/citations?us...) and myself within a collaboration between the Acceleration consortium at UofT and the Institute for Functional Intelligent Materials at NUS.
scholar.google.com
November 25, 2025 at 4:48 PM
looking for a 5y postdoc to work with Stephen Dale (scholar.google.com/citations?us...) and myself within a collaboration between the Acceleration consortium at UofT and the Institute for Functional Intelligent Materials at NUS.
Reposted by Willi
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
November 24, 2025 at 4:57 PM
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
Reposted by Willi
Creating an energy efficient central metabolism for boosting biosynthesis without compromising cell growth of yeast https://www.biorxiv.org/content/10.1101/2025.11.22.689960v1
November 25, 2025 at 2:02 AM
Creating an energy efficient central metabolism for boosting biosynthesis without compromising cell growth of yeast https://www.biorxiv.org/content/10.1101/2025.11.22.689960v1
Reposted by Willi
Workflow orchestration of #SelfDrivingLabs was a hot topic at #Accelerate25. We now organize 2 dedicated workshops on this topic, more details can be found here: www.linkedin.com/posts/willig...
Please get in touch if you want to contribute and shape the future of self-driving labs!
Please get in touch if you want to contribute and shape the future of self-driving labs!
#selfdrivinglabs #accelerate25 #selfdrivinglabs | Willi Gottstein
“𝗪𝗵𝘆 𝗱𝗼 𝘄𝗲 𝗵𝗮𝘃𝗲 𝘀𝗼 𝗺𝗮𝗻𝘆 𝗼𝗿𝗰𝗵𝗲𝘀𝘁𝗿𝗮𝘁𝗶𝗼𝗻 𝘁𝗼𝗼𝗹𝘀? 𝗪𝗵𝘆 𝗮𝗿𝗲 𝗲𝗳𝗳𝗼𝗿𝘁𝘀 𝗳𝗿𝗮𝗴𝗺𝗲𝗻𝘁𝗲𝗱 𝘄𝗵𝗲𝗻 𝘄𝗲 𝗳𝗮𝗰𝗲 𝘁𝗵𝗲 𝘀𝗮𝗺𝗲 𝗰𝗵𝗮𝗹𝗹𝗲𝗻𝗴𝗲𝘀? 𝗜𝘀𝗻’𝘁 𝗶𝘁 𝘁𝗶𝗺𝗲 𝘁𝗼 𝗮𝗹𝗶𝗴𝗻 𝗼𝗻 𝗽𝗿𝗶𝗻𝗰𝗶𝗽𝗹𝗲𝘀 𝗮𝗻𝗱 𝘀𝘁𝗮𝗻𝗱𝗮𝗿𝗱𝘀 𝘁𝗵𝗮𝘁 𝗴𝗼𝘃𝗲𝗿𝗻 𝘄𝗼𝗿𝗸𝗳𝗹𝗼𝘄 𝗼𝗿𝗰𝗵𝗲𝘀𝘁𝗿𝗮𝘁𝗶𝗼𝗻 𝗶𝗻 #𝗦𝗲𝗹𝗳...
www.linkedin.com
November 18, 2025 at 9:18 PM
Workflow orchestration of #SelfDrivingLabs was a hot topic at #Accelerate25. We now organize 2 dedicated workshops on this topic, more details can be found here: www.linkedin.com/posts/willig...
Please get in touch if you want to contribute and shape the future of self-driving labs!
Please get in touch if you want to contribute and shape the future of self-driving labs!
Reposted by Willi
This post is 10 years old at this point. Nothing improved. lucumr.pocoo.org/2016/3/24/op...
Micropackages and Open Source Trust Scaling
Some thoughts about why npm style micro-packages are a huge liability for everybody and what we could do to make them work.
lucumr.pocoo.org
November 24, 2025 at 6:03 PM
This post is 10 years old at this point. Nothing improved. lucumr.pocoo.org/2016/3/24/op...
Reposted by Willi
TorchSim continues its growth aiming to be the high-performance engine for MLIP-powered atomistic simulation.
With this release (4.1), there improvements across the entire stack with new features, bug fixes, and improved documentation.
With this release (4.1), there improvements across the entire stack with new features, bug fixes, and improved documentation.
November 24, 2025 at 6:08 PM
TorchSim continues its growth aiming to be the high-performance engine for MLIP-powered atomistic simulation.
With this release (4.1), there improvements across the entire stack with new features, bug fixes, and improved documentation.
With this release (4.1), there improvements across the entire stack with new features, bug fixes, and improved documentation.
Reposted by Willi
New paper out: An archaeal genetic code with all TAG codons as pyrrolysine: www.science.org/doi/10.1126/...
An archaeal genetic code with all TAG codons as pyrrolysine
Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...
www.science.org
November 23, 2025 at 7:22 PM
New paper out: An archaeal genetic code with all TAG codons as pyrrolysine: www.science.org/doi/10.1126/...
Reposted by Willi
I needed to see which packages were pulling in six.
Two ways:
- uv tree --package six --invert → quick “who depends on this?” from uv.lock
- uv pip tree --package six --invert --show-version-specifiers → more pipdeptree-style, constraint-aware view from the actual env
Two ways:
- uv tree --package six --invert → quick “who depends on this?” from uv.lock
- uv pip tree --package six --invert --show-version-specifiers → more pipdeptree-style, constraint-aware view from the actual env
November 23, 2025 at 1:00 PM
I needed to see which packages were pulling in six.
Two ways:
- uv tree --package six --invert → quick “who depends on this?” from uv.lock
- uv pip tree --package six --invert --show-version-specifiers → more pipdeptree-style, constraint-aware view from the actual env
Two ways:
- uv tree --package six --invert → quick “who depends on this?” from uv.lock
- uv pip tree --package six --invert --show-version-specifiers → more pipdeptree-style, constraint-aware view from the actual env
Reposted by Willi
Lots of interesting LLM releases last week. My fav was actually Olmo 3 (I love the Olmo series due to their full open-sourceness and transparency).
If you are interested in reading through the architecture details, I coded it from scratch here: github.com/rasbt/LLMs-f...
If you are interested in reading through the architecture details, I coded it from scratch here: github.com/rasbt/LLMs-f...
November 23, 2025 at 2:31 PM
Lots of interesting LLM releases last week. My fav was actually Olmo 3 (I love the Olmo series due to their full open-sourceness and transparency).
If you are interested in reading through the architecture details, I coded it from scratch here: github.com/rasbt/LLMs-f...
If you are interested in reading through the architecture details, I coded it from scratch here: github.com/rasbt/LLMs-f...
Reposted by Willi
Every Software Engineer Can Learn TDD (If They Do It Like This) | @emilybache.com
📽️ AVAILABLE NOW
WATCH HERE ➡️ youtu.be/tmOMJhZhIFI
📽️ AVAILABLE NOW
WATCH HERE ➡️ youtu.be/tmOMJhZhIFI
youtu.be
November 19, 2025 at 7:00 PM
Every Software Engineer Can Learn TDD (If They Do It Like This) | @emilybache.com
📽️ AVAILABLE NOW
WATCH HERE ➡️ youtu.be/tmOMJhZhIFI
📽️ AVAILABLE NOW
WATCH HERE ➡️ youtu.be/tmOMJhZhIFI
Reposted by Willi
This “major update to ProteomicsDB” is definitely worth a look. academic.oup.com/nar/advance-...
Mapping drug mechanisms with ProteomicsDB: unified omics and cell sensitivity data at scale
Abstract. Proteomic and phenotypic cell sensitivity datasets are increasingly important for understanding chemoproteomics and the underlying drug mechanism
academic.oup.com
November 22, 2025 at 4:49 AM
This “major update to ProteomicsDB” is definitely worth a look. academic.oup.com/nar/advance-...
Reposted by Willi
Thrilled to share the results of a great collaboration from Cinvestav Mérida, Cinvestav Zacatenco, and the University of Toronto:
Grammar-Driven SMILES Standardization with TokenSMILES.
📜 pubs.rsc.org/en/content/a...
[1/6]
Grammar-Driven SMILES Standardization with TokenSMILES.
📜 pubs.rsc.org/en/content/a...
[1/6]
November 21, 2025 at 8:12 PM
Thrilled to share the results of a great collaboration from Cinvestav Mérida, Cinvestav Zacatenco, and the University of Toronto:
Grammar-Driven SMILES Standardization with TokenSMILES.
📜 pubs.rsc.org/en/content/a...
[1/6]
Grammar-Driven SMILES Standardization with TokenSMILES.
📜 pubs.rsc.org/en/content/a...
[1/6]
Reposted by Willi
Researchers have developed polymeric nanocultures composed of iron-oxide nanoparticles, providing a field-ready approach for cultivating and studying environmental microbes under near-native conditions.
Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4r90UuS
Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4r90UuS
November 21, 2025 at 10:50 PM
Researchers have developed polymeric nanocultures composed of iron-oxide nanoparticles, providing a field-ready approach for cultivating and studying environmental microbes under near-native conditions.
Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4r90UuS
Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4r90UuS
Reposted by Willi
"Docker Registry with Basic Authentication" by Megha Sharma
#docker #cloud-concepts #devops #tech #open-source
#docker #cloud-concepts #devops #tech #open-source
Docker Registry with Basic Authentication
Learn to create a Docker registry with Basic Authentication and Set up your own registry to store, manage, and share Docker images securely within your organization.
community.aws
November 21, 2025 at 12:30 PM
"Docker Registry with Basic Authentication" by Megha Sharma
#docker #cloud-concepts #devops #tech #open-source
#docker #cloud-concepts #devops #tech #open-source
Reposted by Willi
If you use GMail, AI (Gemini) was turned on yesterday by default and now scans all of your content for machine learning. To turn off, go to Settings>General and scroll down. Uncheck the box for "Smart features."
There's other "Smart" add-ons as well, but that's the one that reads your content.
There's other "Smart" add-ons as well, but that's the one that reads your content.
November 20, 2025 at 5:32 PM
If you use GMail, AI (Gemini) was turned on yesterday by default and now scans all of your content for machine learning. To turn off, go to Settings>General and scroll down. Uncheck the box for "Smart features."
There's other "Smart" add-ons as well, but that's the one that reads your content.
There's other "Smart" add-ons as well, but that's the one that reads your content.