@Westermarcklab
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westermarcklab.bsky.social
@Westermarcklab
@westermarcklab.bsky.social
#CIP2A and #Phosphatase biology for cancer therapy @TurkuBioscience @UniTurku
#PP2A #MYC #PME-1 #RAS #Breastcancer #TNBC #Epigenetics
https://bioscience.fi/research/cancer-cell-signaling
https://publons.com/researcher/3571657/jukka-westermarck/
2/2 These results potentially facilitate development of CIP2A inhibitor molecules for therapies in #BRCA mutant cancers, other CIP2A-dependent cancers and in #Alzheimer disease. Very exciting collaboration with groups of Olli Pentikäinen and Ulla Pentikäinen and led by Karolina Pavic.
October 15, 2025 at 5:57 AM
The beautiful image was taken by senior scientist Mari Peltola as part of Thestra´s R&D process to introduce the EPLINEx (the trade name for proprietary LIMA1 assay) IHC assay for clinical #HNSCC diagnostics.
Stay tuned: thestra.fi
Cancer diagnostics company | Thestra
We are a cancer diagnostics company which translates high quality academic research results to patient specific companion diagnostics and therapy stratification solutions.
thestra.fi
August 11, 2025 at 10:50 AM
The results are currently to be turned to a routine IHC diagnostic assay by our Start-up company Thestra Ltd. and we aim to bring the assay to clinical use by 2026.
Stay tuned!
thestra.fi/scientific-b...
Scientific background of Thestra´s EPLINEx™ method in HNSCC diagnosis reported in EMBO Molecular Medicine  | Thestra
Scientific background of Thestra´s EPLINEx™ method is reported in EMBO Molecular Medicine, a leading medical journal.  The findings were validated across all Finnish university hospitals on the use of...
thestra.fi
July 23, 2025 at 7:42 AM
Based on two prospective cohorts, none of the LIMA1-alpha negative HNSCC patients with non-metastatic disease upon diagnosis died during the follow-up.
July 23, 2025 at 7:42 AM
Ps. Some PIs can brag about their 1 million € sequencers, I only got a 100€ sticker printer😅
June 26, 2025 at 10:15 AM
June 3, 2025 at 9:08 AM
Stunning work! Huge Congrats @kusterlab.bsky.social
May 23, 2025 at 2:41 AM