Wessel Burger
@wesselburger.bsky.social
Postdoc at WEHI, Australia. Interested in all things Molecular Pharmacology and Structural Biology of GPCRs
Reposted by Wessel Burger
Cryo-EM reveals an extrahelical allosteric binding site at the M5 mAChR pubmed.ncbi.nlm.nih.gov/40745154/ #cryoem
August 1, 2025 at 12:42 PM
Cryo-EM reveals an extrahelical allosteric binding site at the M5 mAChR pubmed.ncbi.nlm.nih.gov/40745154/ #cryoem
Our latest paper, a whirlwind combination of mutagenesis, GaMD and cryo-EM to find new allosteric binding sites at the M5 mAChR.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 31, 2025 at 11:43 PM
Our latest paper, a whirlwind combination of mutagenesis, GaMD and cryo-EM to find new allosteric binding sites at the M5 mAChR.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An honour and privilege to share my work in this session!
#LorneProteins2025 Anders ECR Awardee Wessel Burger. Studying GPCRs in nanodiscs. Xanomeline: muscarinic acetycholine receptors functionally selective for M4 receptors. Simulated in silico; radiologand binding measured - xanomeline and G protein binding combine to enhance signalling. AND Frizzled 🤯
February 10, 2025 at 10:54 PM
An honour and privilege to share my work in this session!