More than 20 projects at Russell Group institutions halted, freedom of information requests reveal

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Nature Reviews Cancer, Published online: 22 April 2025; doi:10.1038/s41568-025-00814-xIn this Perspective, Kamila Naxerova discusses how genetic analyses of primary tumours and matched metastases can distinguish between competing metastasis evolution models, arguing that further insights into human metastasis biology could be enabled by a framework that rigorously quantifies whether metastases descend from a nonrandom selection of primary tumour lineages.

Background: In normal epithelia Endo180 forms an EMT-suppressor complex with CD147 at the plasma membrane where it functions as a bio-switch for multiple hallma

Breast cancer is the second leading cause of cancer deaths in women in the U.S., killing more than 42,000 last year

On Friday, a memorandum signed by Marco Rubio called for a 90-day cessation of foreign aid. That would likely put on hold the work of PEPFAR, the President's Emergency Plan for AIDS Relief.

Stop Trump Coalition

Unbelievable. Keir Starmer has handed Donald Trump a letter from King Charles, inviting him for a second state visit to the UK. It’s totally unprecedented, and should not go ahead.  This is the...

Hemalatha et al. track the endogenous redox ratio (NAD(P)H/FAD) with live imaging in the mouse skin to study the interface of wild-type stem cells with oncogenic mutant cells. They find that maintaini...

A sabbatical — defined here as an intentional extended leave from your job-related work — may seem out of reach for many workers. But if you can swing it, the potential payoff is enormous. In fact, ta...

Scientists discover the ‘roadmap’ that aggressive cancer uses to spread around the body – identifying ways to block its escape

View details and apply for this Research Assistant vacancy in Sutton. Salary: S ubject to comparable skills and experience . Future progression is based on annual performance rev...

In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic factors induce the epigenetic changes necessary for tumorigenesis.