Guillermo Posadas H.
@viralvector.bsky.social
Post-doc doing research on gene therapy at the Tokyo University, previously worked on arboviral infections.
A little late this year, but I managed to get the yearly calaveras for the lab. 💀
November 4, 2025 at 11:02 PM
A little late this year, but I managed to get the yearly calaveras for the lab. 💀
Looking forward to two days of interesting presentations on the Tokyo University 3rd UTOPIA symposium about vaccine development. Not really my field now that I work on gene therapy but as a virologist can't stop feeling nostalgic.
pub.confit.atlas.jp/en/event/uto...
pub.confit.atlas.jp/en/event/uto...
October 21, 2025 at 12:12 AM
Looking forward to two days of interesting presentations on the Tokyo University 3rd UTOPIA symposium about vaccine development. Not really my field now that I work on gene therapy but as a virologist can't stop feeling nostalgic.
pub.confit.atlas.jp/en/event/uto...
pub.confit.atlas.jp/en/event/uto...
Grant petition finished and submitted, with a lot of help around the lab to make it as good as possible but still a long shot.
September 1, 2025 at 12:57 AM
Grant petition finished and submitted, with a lot of help around the lab to make it as good as possible but still a long shot.
Last week to write this year proposal for the Grants-in-Aid for Scientific Research of the Japanese government.
Not even close to finish but at least the proposal has improved very importantly over the last couple of weeks.
I have no idea how likely it is that it will be granted but doing my best!
Not even close to finish but at least the proposal has improved very importantly over the last couple of weeks.
I have no idea how likely it is that it will be granted but doing my best!
August 22, 2025 at 1:15 AM
Last week to write this year proposal for the Grants-in-Aid for Scientific Research of the Japanese government.
Not even close to finish but at least the proposal has improved very importantly over the last couple of weeks.
I have no idea how likely it is that it will be granted but doing my best!
Not even close to finish but at least the proposal has improved very importantly over the last couple of weeks.
I have no idea how likely it is that it will be granted but doing my best!
Nice afternoon at the local summer festival 🪭☀️
July 27, 2025 at 11:07 AM
Nice afternoon at the local summer festival 🪭☀️
Explosion on Saitama University lab during experiments, fortunately it seems victims had only minor injuries.
I can already see the e-mails that will come from the safety management office of my university...
I can already see the e-mails that will come from the safety management office of my university...
【速報】埼玉大学でボンベ爆発 教員1人が負傷、実験中か 学生1人は爆風で体調不良
【速報】埼玉大学でボンベ爆発 教員1人が負傷、実験中か 学生1人は爆風で体調不良
9日午前11時過ぎ、埼玉県さいたま市桜区の埼玉大学で、教員から「実験中のボンベが爆発した」と119番があった。大学やさいたま市消防局によると、爆発は大学内の工学部実習工場・研究実験棟の南側にある屋外 ...
www.47news.jp
July 9, 2025 at 6:08 AM
Explosion on Saitama University lab during experiments, fortunately it seems victims had only minor injuries.
I can already see the e-mails that will come from the safety management office of my university...
I can already see the e-mails that will come from the safety management office of my university...
Reposted by Guillermo Posadas H.
If we trust genetic engineering to save a child from leukemia, why reject it when it could save a child from blindness, malnutrition, or death?
We cure cancer with genetic engineering but ban it on the farm.
Celebrating one but demonizing the other fuels disinformation that costs lives.
1/
We cure cancer with genetic engineering but ban it on the farm.
Celebrating one but demonizing the other fuels disinformation that costs lives.
1/
June 24, 2025 at 10:26 PM
If we trust genetic engineering to save a child from leukemia, why reject it when it could save a child from blindness, malnutrition, or death?
We cure cancer with genetic engineering but ban it on the farm.
Celebrating one but demonizing the other fuels disinformation that costs lives.
1/
We cure cancer with genetic engineering but ban it on the farm.
Celebrating one but demonizing the other fuels disinformation that costs lives.
1/
Reposted by Guillermo Posadas H.
Ticks are spreading globally and bringing familiar conditions such as Lyme disease with them, as well as totally new ones. Now research is revealing how to prevent and treat the diseases they carry.
Why Lyme disease and other tick-borne conditions are on the rise
www.newscientist.com
June 19, 2025 at 11:02 PM
Ticks are spreading globally and bringing familiar conditions such as Lyme disease with them, as well as totally new ones. Now research is revealing how to prevent and treat the diseases they carry.
Reposted by Guillermo Posadas H.
Your genome is not a blueprint. A thread about misleading metaphors in science communication. 🧬🧪 1/n
June 14, 2025 at 3:50 PM
Your genome is not a blueprint. A thread about misleading metaphors in science communication. 🧬🧪 1/n
50 days for the annual meeting of the Japan Society of Gene and Cell Therapy! still swamped on things to do but looking forward to it.
square.umin.ac.jp/jsgct2025/en...
square.umin.ac.jp/jsgct2025/en...
The 31st Annual Meeting of Japan Society of Gene and Cell Therapy (JSGCT2025) | Do Convention inc.
July 23(Wed.) - 25(Fri.), HOTEL GAJOEN TOKYO , The 31st Annual Meeting of Japan Society of Gene and Cell Therapy(JSGCT2025), THEME：- Great Expectations - International Contributions and the Cusp of a...
square.umin.ac.jp
June 3, 2025 at 4:58 AM
50 days for the annual meeting of the Japan Society of Gene and Cell Therapy! still swamped on things to do but looking forward to it.
square.umin.ac.jp/jsgct2025/en...
square.umin.ac.jp/jsgct2025/en...
Reposted by Guillermo Posadas H.
⚠️ Discovery of a new mode of viral transmission:
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
May 10, 2025 at 8:12 AM
⚠️ Discovery of a new mode of viral transmission:
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
Deltaviruses spread through a viral Trojan Horse !
These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!
www.biorxiv.org/content/10.1...
A thread 1/14
Time-lapse of the Cherry blossom in the campus on the last week, full bloom just in time for the Hanami party tomorrow🌸#花見
April 16, 2025 at 1:48 AM
Time-lapse of the Cherry blossom in the campus on the last week, full bloom just in time for the Hanami party tomorrow🌸#花見
Three more months until the annual meeting of the Japanese Society of Gene and Cell Therapy in Tokyo.
Regular abstract submission already closed, but there is still a chance to submit "Late breaking abstracts" for poster presentation until the end of April!
square.umin.ac.jp/jsgct2025/en...
Regular abstract submission already closed, but there is still a chance to submit "Late breaking abstracts" for poster presentation until the end of April!
square.umin.ac.jp/jsgct2025/en...
The 31st Annual Meeting of Japan Society of Gene and Cell Therapy (JSGCT2025) | Do Convention inc.
July 23(Wed.) - 25(Fri.), HOTEL GAJOEN TOKYO , The 31st Annual Meeting of Japan Society of Gene and Cell Therapy(JSGCT2025), THEME：- Great Expectations - International Contributions and the Cusp of a...
square.umin.ac.jp
April 10, 2025 at 2:27 AM
Three more months until the annual meeting of the Japanese Society of Gene and Cell Therapy in Tokyo.
Regular abstract submission already closed, but there is still a chance to submit "Late breaking abstracts" for poster presentation until the end of April!
square.umin.ac.jp/jsgct2025/en...
Regular abstract submission already closed, but there is still a chance to submit "Late breaking abstracts" for poster presentation until the end of April!
square.umin.ac.jp/jsgct2025/en...
Wow, I can't remember snow this late in March in all my years living in Tokyo ❄️🗼
March 18, 2025 at 11:45 PM
Wow, I can't remember snow this late in March in all my years living in Tokyo ❄️🗼
Reposted by Guillermo Posadas H.
Suddenly spring begins on campus...
March 13, 2025 at 10:00 AM
Suddenly spring begins on campus...
Reposted by Guillermo Posadas H.
Unbelievable news.
Pancreatic is one of the deadliest cancers.
New paper shows personalized mRNA vaccines can induce durable T cells that attack pancreatic cancer, with 75% of patients cancer free at three years—far, far better than standard of care.
www.nature.com/articles/s41...
Pancreatic is one of the deadliest cancers.
New paper shows personalized mRNA vaccines can induce durable T cells that attack pancreatic cancer, with 75% of patients cancer free at three years—far, far better than standard of care.
www.nature.com/articles/s41...
February 27, 2025 at 5:03 PM
Unbelievable news.
Pancreatic is one of the deadliest cancers.
New paper shows personalized mRNA vaccines can induce durable T cells that attack pancreatic cancer, with 75% of patients cancer free at three years—far, far better than standard of care.
www.nature.com/articles/s41...
Pancreatic is one of the deadliest cancers.
New paper shows personalized mRNA vaccines can induce durable T cells that attack pancreatic cancer, with 75% of patients cancer free at three years—far, far better than standard of care.
www.nature.com/articles/s41...
Extraordinary!
Makes it easier to be optimistic about these kind of interventions.
Makes it easier to be optimistic about these kind of interventions.
The alternate splicing small molecule risdiplam, administered to a fetus with spinal muscular atrophy, had an apparent ameliorating effect on the disorder through 30 months. Learn more: nej.md/3XbEg7J
#MedSky #Neurology #PedSky
#MedSky #Neurology #PedSky
Risdiplam for Prenatal Therapy of Spinal Muscular Atrophy | NEJM
The alternate splicing small molecule risdiplam, administered to a fetus with spinal
muscular atrophy, had an apparent ameliorating effect on the disorder through 30 months.
nej.md
February 20, 2025 at 7:41 AM
Extraordinary!
Makes it easier to be optimistic about these kind of interventions.
Makes it easier to be optimistic about these kind of interventions.
I guess this weekend was not the best time to watch the Bell riots episodes of DS9...
February 16, 2025 at 2:59 AM
I guess this weekend was not the best time to watch the Bell riots episodes of DS9...
Reposted by Guillermo Posadas H.
The Indigenous People of North America have decided to go back to calling the Gulf of Mexico, “Chalchiuhtlicueyecatl”. It is what the Nahuatl People originally called it as it is the domain of the goddess Chalchiuhtlicue, who is assoc w/water bodies, including the Gulf of Mexico.
February 14, 2025 at 7:07 AM
The Indigenous People of North America have decided to go back to calling the Gulf of Mexico, “Chalchiuhtlicueyecatl”. It is what the Nahuatl People originally called it as it is the domain of the goddess Chalchiuhtlicue, who is assoc w/water bodies, including the Gulf of Mexico.
I really like the Research Findings Presentation meeting of my institute, which is leading research in several very interesting areas from organoid transplantation to oncolytic vaccines. It really turns on the "motivation switch", maybe I can present something like that next year?
February 14, 2025 at 8:20 AM
I really like the Research Findings Presentation meeting of my institute, which is leading research in several very interesting areas from organoid transplantation to oncolytic vaccines. It really turns on the "motivation switch", maybe I can present something like that next year?
Reposted by Guillermo Posadas H.
In a new phase 2 trial, researchers evaluated the efficacy of a gene-editing therapy, NTLA-2002, in preventing angioedema attacks in patients with hereditary angioedema. Full trial results and Plain Language Summary: nej.md/4heR7hT
#MedSky #Oncology
#MedSky #Oncology
February 4, 2025 at 8:31 PM
In a new phase 2 trial, researchers evaluated the efficacy of a gene-editing therapy, NTLA-2002, in preventing angioedema attacks in patients with hereditary angioedema. Full trial results and Plain Language Summary: nej.md/4heR7hT
#MedSky #Oncology
#MedSky #Oncology
Reposted by Guillermo Posadas H.
🚨New paper alert! 🚨 Our latest work in
@cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇
sciencedirect.com/science/arti...
@cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇
sciencedirect.com/science/arti...
In vivo engineering of murine T cells using the evolved adeno-associated virus variant Ark313
Genetic engineering of T cells in mouse models is essential for investigating immune mechanisms. We aimed to develop an approach to manipulate T cells…
sciencedirect.com
February 4, 2025 at 8:50 PM
🚨New paper alert! 🚨 Our latest work in
@cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇
sciencedirect.com/science/arti...
@cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇
sciencedirect.com/science/arti...
Reposted by Guillermo Posadas H.
Movies as paper titles:
Splinter, M. et al. (1990). "Traditional ninjitsu training increases overall survivability (OS) in an adolescent cohort of wood turtles, Glyptemys insculpta, exposed to ionizing radiation in the New York sewer system." Rept Gen. 90(6):407-409.
Splinter, M. et al. (1990). "Traditional ninjitsu training increases overall survivability (OS) in an adolescent cohort of wood turtles, Glyptemys insculpta, exposed to ionizing radiation in the New York sewer system." Rept Gen. 90(6):407-409.
January 29, 2025 at 4:08 PM
Movies as paper titles:
Splinter, M. et al. (1990). "Traditional ninjitsu training increases overall survivability (OS) in an adolescent cohort of wood turtles, Glyptemys insculpta, exposed to ionizing radiation in the New York sewer system." Rept Gen. 90(6):407-409.
Splinter, M. et al. (1990). "Traditional ninjitsu training increases overall survivability (OS) in an adolescent cohort of wood turtles, Glyptemys insculpta, exposed to ionizing radiation in the New York sewer system." Rept Gen. 90(6):407-409.