Vinod Scaria
@vinodscaria.bsky.social
Scientist, Former Doctor , Technology Enthusiast .
#RareDisease #Oncology #PopulationGenomics #Genomics4All
https://vinodscaria.genomes.in
#RareDisease #Oncology #PopulationGenomics #Genomics4All
https://vinodscaria.genomes.in
Researchers at Sanger Institute in the UK have used genomic tools to unravel the chemotherapy mutograph in hematopoietic stem cells
Read the complete article at sciencechronicle.in/2025/07/08/a...
Read the complete article at sciencechronicle.in/2025/07/08/a...
A genomic view of DNA damage in chemotherapy
Seventeen of 23 individuals exposed to chemotherapy had far more genetic mutations than could be explained by normal aging. Even more revealing was the discovery of eight unique mutational signatur…
sciencechronicle.in
July 8, 2025 at 6:53 PM
Researchers at Sanger Institute in the UK have used genomic tools to unravel the chemotherapy mutograph in hematopoietic stem cells
Read the complete article at sciencechronicle.in/2025/07/08/a...
Read the complete article at sciencechronicle.in/2025/07/08/a...
Carriers face a significantly higher risk (2-4x) of heart failure, cardiomyopathy, and arrhythmias.
This underscores the potential of genetic screening for early detection and intervention.
www.ahajournals.org/doi/10.1161/...
This underscores the potential of genetic screening for early detection and intervention.
www.ahajournals.org/doi/10.1161/...
Association of Pathogenic/Likely Pathogenic Genetic Variants for Cardiomyopathies With Clinical Outcomes: A Multiancestry Analysis in the All of Us Research Program | Circulation: Genomic and Precisio...
BACKGROUND: This study aimed to evaluate the prevalence of pathogenic/likely pathogenic cardiomyopathy
variant carriers in a multiancestry US population and examine the risk of adverse
clinical outcom...
www.ahajournals.org
May 30, 2025 at 7:11 PM
Carriers face a significantly higher risk (2-4x) of heart failure, cardiomyopathy, and arrhythmias.
This underscores the potential of genetic screening for early detection and intervention.
www.ahajournals.org/doi/10.1161/...
This underscores the potential of genetic screening for early detection and intervention.
www.ahajournals.org/doi/10.1161/...
Hi. Would you be able to share a preprint or PDF at drvinod(at)gmail.thanks in advance.
May 27, 2025 at 3:39 PM
Hi. Would you be able to share a preprint or PDF at drvinod(at)gmail.thanks in advance.
The virus was first isolated in Netherlands in 2001 children with respiratory tract infections. Serological studies by the authors suggested that by the age of 5 years, virtually all children in the Netherlands have been exposed to human metapneumovirus.
pubmed.ncbi.nlm.nih.gov/11385510/
pubmed.ncbi.nlm.nih.gov/11385510/
A newly discovered human pneumovirus isolated from young children with respiratory tract disease - PubMed
From 28 young children in the Netherlands, we isolated a paramyxovirus that was identified as a tentative new member of the Metapneumovirus genus based on virological data, sequence homology and gene ...
pubmed.ncbi.nlm.nih.gov
January 4, 2025 at 10:57 AM
The virus was first isolated in Netherlands in 2001 children with respiratory tract infections. Serological studies by the authors suggested that by the age of 5 years, virtually all children in the Netherlands have been exposed to human metapneumovirus.
pubmed.ncbi.nlm.nih.gov/11385510/
pubmed.ncbi.nlm.nih.gov/11385510/
In fact hMPV is quite prevalent with estimates of almost 1 in 10 of all lower respiratory tract infections in the US
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Human Metapneumovirus and Lower Respiratory Tract Disease in Otherwise Healthy Infants and Children | NEJM
We sought to determine the role of human metapneumovirus in lower respiratory tract
illness in previously healthy infants and children. We tested nasal-wash specimens,
obtained over a 25-year perio...
www.nejm.org
January 4, 2025 at 10:57 AM
In fact hMPV is quite prevalent with estimates of almost 1 in 10 of all lower respiratory tract infections in the US
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
The severity of the disease is similar to that of RSV. Severe disease is seen in children as well as elderly, apart from individuals with compromised immunity
hMPV shows a seasonal pattern, with the peak infections during winter.
hMPV shows a seasonal pattern, with the peak infections during winter.
January 4, 2025 at 10:57 AM
The severity of the disease is similar to that of RSV. Severe disease is seen in children as well as elderly, apart from individuals with compromised immunity
hMPV shows a seasonal pattern, with the peak infections during winter.
hMPV shows a seasonal pattern, with the peak infections during winter.
Short answer first : No
Follow the rest of the thread only if you would like to know more and understand in detail.
Human Metapneumovirus (hMPV) is not a new virus. It was first isolated in 2001 and a very prevalent viruscausinh mild infections, usually similar to the common cold or flu
Follow the rest of the thread only if you would like to know more and understand in detail.
Human Metapneumovirus (hMPV) is not a new virus. It was first isolated in 2001 and a very prevalent viruscausinh mild infections, usually similar to the common cold or flu
January 4, 2025 at 10:57 AM
Short answer first : No
Follow the rest of the thread only if you would like to know more and understand in detail.
Human Metapneumovirus (hMPV) is not a new virus. It was first isolated in 2001 and a very prevalent viruscausinh mild infections, usually similar to the common cold or flu
Follow the rest of the thread only if you would like to know more and understand in detail.
Human Metapneumovirus (hMPV) is not a new virus. It was first isolated in 2001 and a very prevalent viruscausinh mild infections, usually similar to the common cold or flu