viet
viet5.bsky.social
viet
@viet5.bsky.social

Postdoctoral Fellow at Boston Children's Hospital and Harvard Medical School


Passionate M.D. Ph.D. | Neuroscience Enthusiast | Circadian Rhythm Metabolism Fitness & Retinal Ganglion Cell Research
Recent review in Cell dives into the connections between brain and body, exploring how they communicate through local, reflexive, and central pathways. This review shows how the brain processes internal signals to coordinate bodily responses in immune and inflammatory.
www.cell.com/cell/fulltex...
November 18, 2024 at 2:05 PM
Ketones signal "fat sufficiency" to the brain! The "β-hydroxybutyrate (BHB) shunt pathway" explains why fasting, ketogenic diet reduces hunger. BHB-derived metabolites activate brain regions like the hypothalamus and brainstem, suppressing food intake and weight gain.
www.cell.com/cell/fulltex...
A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites
Conserved ketone body-amino acid metabolites suppress food intake in mice, demonstrating that secondary ketone body metabolism contributes to energy balance.
www.cell.com
November 14, 2024 at 12:42 PM
Not the brain but the gut drives fat cravings!"Gut–brain circuits for fat preference" reveals how gut signals, not taste, drive fat cravings. Fat activates gut neurons, signaling the brain bypassing taste. Fasting may reset these circuits, reshaping food preferences! www.nature.com/articles/s41...
Gut–brain circuits for fat preference - Nature
Behavioural and genetic experiments in mice reveal gut-to-brain circuits driving the development of fat preference, one responding to intestinal sugar and fat using cholecystokinin signalling,&nb...
www.nature.com
November 13, 2024 at 2:51 PM
Watching the sunset 🌅 is the best way to set your brain 🧠 into the dark phase 🌌✨- Brookline from Pierce Boston
November 13, 2024 at 12:50 AM
Fascinating paper in Nature explores the effects of combine caloric restriction and intermittent fasting on lifespan and genetic factors! This reveals that while both approaches extend lifespan, genetic factors have a larger impact on longevity than diet. Check it out: www.nature.com/articles/s41...
Dietary restriction impacts health and lifespan of genetically diverse mice - Nature
Health effects of dietary restriction are uncoupled from longevity.
www.nature.com
November 13, 2024 at 12:33 AM