Tom Williams
@tweethinking.bsky.social
170 followers
81 following
15 posts
Computational evolutionary biologist - phylogenetics, molecular and microbial evolution
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Reposted by Tom Williams
Reposted by Tom Williams
Reposted by Tom Williams
Sishuo Wang
@sishuowang.bsky.social
· Jul 11
New Ways to Root Phylogenomic trees: the Smart, the symbiotic, the violent
To root a phylogenomic tree is very important to study the evolutionary relationship between species. However, typically the substitution models (say GTR, LG, etc.) people use are time-reversible m…
sishuowang2022.wordpress.com
Tom Williams
@tweethinking.bsky.social
· Jun 17
📣 We are proud of the publication of the second paper of @bbaker24.bsky.social PhD thesis. In collaboration with friends in Halifax we have studied the difficult question of the phylogeny of the DPANN archaea, composed of several phyla of highly reduced, fast-evolving epiparasites 🧵
rdcu.be/erkkU
rdcu.be/erkkU
Phylogenomic analyses indicate the archaeal superphylum DPANN originated from free-living euryarchaeal-like ancestors
Nature Microbiology - Phylogenetic reconstructions with conserved protein markers from the 11 known DPANN phyla reveal their monophyletic placement within the Euryarchaeota.
rdcu.be
Reposted by Tom Williams
Reposted by Tom Williams
Tom Williams
@tweethinking.bsky.social
· Mar 20
Out today: Exciting intermediate between endosymbiont and organelle identified! Endosymbionts in Angomonas deanei lost nearly all bacterial cell division genes. Instead, we identified a host-encoded protein, ETP9, that became specialized for endosymbiont division. 1/2
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Tom Williams
Alexis Stamatakis
@stamatak.bsky.social
· Mar 19
raxtax: A k-mer-based non-Bayesian Taxonomic Classifier
Taxonomic classification in biodiversity studies is the process of assigning the anonymous sequences of a marker gene (barcode) to a specific lineage using a reference database that contains named seq...
www.biorxiv.org
Tom Williams
@tweethinking.bsky.social
· Mar 19
Diversification, niche adaptation, and evolution of a candidate phylum thriving in the deep Critical Zone | PNAS
The deep subsurface soil microbiome encompasses a vast amount of understudied phylogenetic
diversity and metabolic novelty, and the metabolic capab...
www.pnas.org
Tom Williams
@tweethinking.bsky.social
· Mar 12
A robustly rooted tree of eukaryotes reveals their excavate ancestry - Nature
The root of the eukaryote Tree of Life is estimated from a new, larger dataset of mitochondrial proteins including all known eukaryotic supergroups, showing it lies between two multi-supergroup assemb...
www.nature.com
Tom Williams
@tweethinking.bsky.social
· Feb 18
Tom Williams
@tweethinking.bsky.social
· Feb 17
Tom Williams
@tweethinking.bsky.social
· Feb 17
Tom Williams
@tweethinking.bsky.social
· Feb 17
Phylogenomic analyses reveal that Panguiarchaeum is a clade of genome-reduced Asgard archaea
The Asgard archaea are a diverse archaeal phylum that includes the host lineage from which eukaryotes evolved. Due to the importance of the Asgard archaea for our understanding of cellular evolution a...
www.biorxiv.org
Reposted by Tom Williams
Happy to share our paper’s final version on the evolution, structure, and membrane binding / remodeling of Asgard ESCRT-III proteins! And my first 🦋 post! www.science.org/doi/10.1126/...
Asgard archaea reveal the conserved principles of ESCRT-III membrane remodeling
Asgard archaea have two ESCRT-III subunits with the conserved traits that drive stepwise membrane remodeling in eukaryotes.
www.science.org
Reposted by Tom Williams
Wow! A real honour to be included on this year's list, thanks @quantamagazine.bsky.social and of course all the vital collaborators involved in the work youtu.be/p9XHI_26cPE?...
2024's Biggest Breakthroughs in Biology and Neuroscience
YouTube video by Quanta Magazine
youtu.be