tree_of_lfie
tree-of-life.bsky.social
tree_of_lfie
@tree-of-life.bsky.social
原核生物のゲノム配列を学習させた4,500億トークンのゲノム言語モデルEVO1.5を構築
- 9,000種類の機能プロンプトに対して, 新規なDNA配列(ひいてはドメインやタンパク質)をレスポンスする1,200億-bp規模の合成遺伝子データベースSynGenomeを構築・公開
crisp-bio.blog.jp/archives/396...
November 21, 2025 at 12:33 PM
“Human Body Single-Cell Atlas of 3D Genome Organization and DNA Methylation"
Zhou J, Wu Y [..] Dixon JR, Ecker JR. bioRxiv 2025-03-24 (preprint).
 doi.org/10.1101/2025...
Human Cell Epigenome Atlas
humancellepigenomeatlas.arcinstitute.org
March 31, 2025 at 11:23 PM
"A human brain map of mitochondrial respiratory capacity and diversity" Mosharov EV [..] Thiebaut de Schotten M, Picard M. 
Nature 2024-03-26. 
doi.org/10.1038/s415...
MitoBrainMap humanmitobrainmap.bcblab.com
March 31, 2025 at 11:22 PM
NEWS "Arc Virtual Cell Atlas launches, combining data from over 300 million cells" 
Arc Institute. 2025-02-25 arcinstitute.org/news/news/ar...
March 31, 2025 at 11:21 PM
Perspective "How to build the virtual cell with artificial intelligence: Priorities and opportunities"
Bunne C, Roohani Y, Rosen Y [..] Karaletsos T, Regev A, Lundberg E, Leskovec J, Quake SR. 
Cell. 2024-12-12.  
doi.org/10.1016/j.ce...
March 31, 2025 at 11:21 PM
"SPEAR: CRISPR-mediated ultrasensitive, specific and rapid one-pot detection strategy for cancer-related SNPs"
Bai L, Pang Y, Wang T [..] Jin G, Wang R.
Theranostics. 2025-02-18.
doi.org/10.7150/thno...
SPEAR(Specific Point mutation Evaluation via CRISPR-Cas Assisted Recognition)
March 23, 2025 at 10:01 PM
"Novel adaptive immune systems in pristine Antarctic soils"
Van Goethem MW [..] Makhalanyane TP.
Sci Rep. 2025-01-18.
doi.org/10.1038/s415...
CRISPR-Cas systems provide evidence of virus attacks in Antarctica.
January 28, 2025 at 8:30 AM
"eDNA tech tracks lethal jellyfish with CRISPR precision"
Osathanunkul M. Ecol Inform. 2025-01-15.
doi.org/10.1016/j.ec...
CRISPR-Cas12a eDNA system
January 26, 2025 at 2:57 AM