Imagine you want to make a map of the US but don't have satellites, just distances between cities. This method works the same way. DNA barcodes diffuse under UV light, and UMAP is used to reconstruct the tissue map, creating a spatial map without imaging.

No microscope? No problem! A new spatial transcriptomics method developed at the Broad lets you map gene expression with zero imaging needed. Perfect for big tissue samples and small labs! 🔬💡 #spatialtranscriptomics #bioinformatics #transcriptomics #genomics #biology #harvard #broadinstitute