Thanks Shireen!

This has been a great collaboration @fuller-lab.bsky.social @manuelsalmeron.bsky.social @marcocantini.bsky.social Joe Swift @uofglasgow.bsky.social @fabqu.bsky.social @uofgscmh.bsky.social @uofgmvls.bsky.social

We explore shared molecular signatures between Col4a1 mutant hearts and common cardiac disease proteomics datasets, highlighting key overlapping mechanistic pathways enforcing the critical function of cardiac basement membranes.

She describes a novel cardiac phenotype attributed to Col4a1 mutations underlined by the development of cardiac fibrosis, reduced contractile capacity and biomechanical alterations.
Proteomic analysis revealed several altered cardiac metabolism and sarcomere formation pathways 📉📈

Congrats Yoshi! Was good to see you last week at the collagen Gordon conference...

Here's what it gets you

Congrats Alex and @valerioizzi.bsky.social! Was great to see you both at the Collagen Gordon meeting and thank you for participating in the power hour