Tom Elliot
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tom-elliot.bsky.social
Tom Elliot
@tom-elliot.bsky.social
Postdoc @WorboysLab.bsky.social @LydiaBeckeriii.bsky.social investigating how checkpoint receptors regulate T cell function
Reposted by Tom Elliot
The deadline for this PhD is fast approaching. We are looking for a promising synthetic chemist to make new chemical biology tools to learn more about nucleic acid interactions. This is a collaborative project with the Trowbridge Lab in @uomscieng.bsky.social. If interested, get in touch soon!
May 29, 2025 at 3:30 PM
Reposted by Tom Elliot
Really humbled to have been selected by @iuis-online.bsky.social for their rising stars initiative and to be given the opportunity to present at their Congress in Austria this year! 🥳🥳🥳 #immunosky 🧪
May 22, 2025 at 7:48 PM
Reposted by Tom Elliot
Our latest research is now available as a pre-print at BioRxiv. We show that the immune checkpoint receptor TIGIT cannot signal in T cells without simultaneous TCR stimulation.

#ImmunoSky

www.biorxiv.org/content/10.1...
Inhibitory TIGIT signalling is dependent on T cell receptor activation
TIGIT is an immune checkpoint receptor that can signal via cytoplasmic ITT-like and ITIM motifs to regulate T cell function. The signalling molecules that mediate inhibitory TIGIT signalling in T cell...
www.biorxiv.org
May 14, 2025 at 7:50 AM
Reposted by Tom Elliot
PD1 & Lag3 regulate TCR signal duration in tolerant CD4 T cells
•PD-1 & Lag3 exhibit layered control of CD4 T cell activation
•Co-blockade enhances NFAT-dependent TCR transcription
•NFAT inhibition reverses functional effects of anti-PD-1&Lag3
doi.org/10.1093/immadv/ltaf015
@imtadvances.bsky.social
May 12, 2025 at 8:03 AM
Reposted by Tom Elliot
Now published @cp-iscience.bsky.social
Work lead by David Lecky & Lozan Sheriff in collaboration with @therad-lab.bsky.social and @cameron-wraith.bsky.social showing how IFNg augments T Cell receptor signal strength to enhance type 1 Regulatory T (Tr1) cell development

www.cell.com/iscience/ful...
April 11, 2025 at 7:21 AM
Reposted by Tom Elliot
Our lab has a postdoc position available to use super-resolution microscopy to understand how nanoscopic localisation of immune checkpoints dictates their function.

Please get in touch if interested in applying.

www.jobs.manchester.ac.uk/Job/JobDetai...

#ImmunoSky #Imaging #Microscopy
Research Associate in Imaging Human Immunology:Oxford Road
www.jobs.manchester.ac.uk
March 26, 2025 at 4:15 PM
Reposted by Tom Elliot
New postdoc position in @frances-turrell.bsky.social lab. Great opportunity to join a new group, doing exciting work 🧪

Get in touch if you want to chat about life in the lab (it's fab)!

www.jobs.manchester.ac.uk/Job/JobDetai...

#ImmunoSky
Research Associate in Breast Cancer Metastasis:CRUK Oglesby Cancer Research Building, 555 Wilmslow Road, M20 4GJ
www.jobs.manchester.ac.uk
March 26, 2025 at 8:46 AM
Reposted by Tom Elliot
Super privileged to be working on such an interesting and important project!

Working out how tumour cell dormancy is regulated is critical to managing reawakening and mitigating this risk for patients. Watch this space for some exciting experiments 🧪

#ImmunoSky #CancerResearch
February 20, 2025 at 5:49 PM
Reposted by Tom Elliot
Online now, our latest manuscript reporting findings on the metabolic basis of cytokine-driven CD4+ T cell expansion, assessed in vitro and during T cell proliferation following autologous stem cell transplantation.

www.sciencedirect.com/science/arti...
IL-7 promotes integrated glucose and amino acid sensing during homeostatic CD4+ T cell proliferation
Interleukin (IL)-7 promotes T cell expansion during lymphopenia. We studied the metabolic basis in CD4+ T cells, observing increased glucose usage for…
www.sciencedirect.com
January 20, 2025 at 1:13 PM
Reposted by Tom Elliot
🚨 The Menon lab is hiring a postdoc!

Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @ukri.org @lydiabeckeriii.bsky.social

Please help spread the word #ImmunoSky

www.jobs.manchester.ac.uk/Job/JobDetai...
Research Associate in Mucosal Immunology :Manchester
www.jobs.manchester.ac.uk
January 16, 2025 at 6:40 PM
Reposted by Tom Elliot
There's still time to apply for this postdoc position in our lab. Ideally suited to someone wanting to develop some independent research, we have lots of new projects to select from! #immunosky 🧪
We're hiring! 3 year post-doc position available in the lab on fungal adaptation to the host. Funded by Wellcome Trust, working closely with the group of Becky Hall at Kent. Informal enquiries welcome - further details in link below. #immunosky 🧪🍄
uk.indeed.com/m/viewjob?jk...
Research Fellow - Department of Immunology and Immunotherapy - 104822 - Grade 7 - Birmingham - Indeed.com
University of Birmingham
uk.indeed.com
December 16, 2024 at 11:03 AM
Reposted by Tom Elliot
PD-1 and Lag3 pathways converge to additively regulate TCR signal duration and NFAT-dependent transcriptional activity during early CD4+ T cell re-activation
www.biorxiv.org/content/10.1...
December 16, 2024 at 3:30 AM
Really enjoyed being back in Birmingham for a day for my graduation ☺️ Feeling very grateful for the people that helped me through my PhD last few years
December 11, 2024 at 3:04 PM