Tim Morris
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timpmorris.bsky.social
Tim Morris
@timpmorris.bsky.social
2.4K followers 460 following 1.5K posts
Biostatistician working on methodology at Novartis. Simulation studies, non-inferiority, missing data, estimands, covariate adjustment…
He/him
https://tpmorris.substack.com/
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timpmorris.bsky.social
Hang on… I added "font" to show that this isn’t because it’s ambiguous.
Screenshot of my google search for "univers font"
November 11, 2025 at 11:17 AM
timpmorris.bsky.social
Perhaps only if they’re on google fonts?
Screenshot of google search for "univers"
November 11, 2025 at 11:15 AM
timpmorris.bsky.social
Does this enrage you too? Publishers adding a random page nobody wants at the beginning of a pdf, bigger than the rest of the pages – the ones people actually want to read – messing up the fit-to-width size of pages you do want to read! Just making readers’ lives pointlessly difficult.
Screenshot of a pdf with a random big title page before the paper begins Another screenshot of a pdf with a random big title page before the paper begins.
November 11, 2025 at 11:13 AM
timpmorris.bsky.social
Classic bit of pathetic fallacy here from my gluten-free bread
Two slices of gluten-free bread with large air pocket at the bottom making the shape of an intensely sad mouth
October 10, 2025 at 8:42 AM
timpmorris.bsky.social
New (short) post on hearing criticism of your work.

No, I’m not telling you who it was – they will recognise themself!

open.substack.com/pub/tpmorris...
October 8, 2025 at 4:17 PM
timpmorris.bsky.social
The defenders of British Values, having completed their work assaulting police officers, have returned home, leaving London a Dystopian Hellscape once again
The morning sun peeping around some horse chestnuts (non-native) and hornbeams (non-native)
September 15, 2025 at 8:33 AM
timpmorris.bsky.social
😜
September 11, 2025 at 9:17 AM
timpmorris.bsky.social
I’m just a bit baffled about what you think this is “inferior to”. Writing an subsequent expression in terms of potential outcomes? If so, this should come from the natural-language version, not compete with it.
E.g. doi.org/10.1002/sim....
September 11, 2025 at 8:46 AM
timpmorris.bsky.social
Thanks Cameron!
Dean, two key points:
1. It’s the structure in this pic that we all find so useful.
2. The “Intercurrent event strategies” mean interplay with the other four attributes.
Screenshot of a slide. Title: “Addendum contributions (‘IMO’)” Left hand column says “Five ‘attributes’ 1. Treatment condition of interest 2. Target population 3. Outcome variable 4. Intercurrent events 5. Population-level summary measure” Right hand column says “Handling intercurrent events (LHS point 4) 1. ‘Treatment policy’ 2. ‘Hypothetical’ 3. ‘Composite variable’ 4. ‘While on treatment’ 5. Principal stratum”
September 10, 2025 at 2:16 PM
timpmorris.bsky.social
Interesting discussion with collaborators about whether it’s acceptable to say anything negative about PPI.
They showed a quote that seems like a huge “therefore” lurch!
1/
researchinvolvement.biomedcentral.com/articles/10....
September 5, 2025 at 10:53 AM
timpmorris.bsky.social
I already think John Baker will be impressed. Can you help my friend out and improve on it?
September 1, 2025 at 9:32 AM
timpmorris.bsky.social
ISCB46 has been really fun. So much that I’ve barely been on here.

Admittedly “bRave little soldieRs” probably shouldn’t have made it into the slides but IN MY DEFENCE I MADE THEM WITH QUARTO 😇
August 27, 2025 at 9:32 PM
timpmorris.bsky.social
Post just up: Is multiple imputation making up information?

tldr: no.

Includes a cheeky simulation study to demonstrate the point.
open.substack.com/pub/tpmorris...
Cover picture with blog title & subtitle, and results graph in the background
July 23, 2025 at 3:29 PM
timpmorris.bsky.social
I’m glad you brought up sons. All the good photos I get are with my son, which you can’t use as a headshot. Also true of sunglasses.
July 22, 2025 at 9:22 PM
timpmorris.bsky.social
Reckon I can submit this as a figure for a paper?
Goose chase meme. Goose asks "Unbiased for what estimand?" then yells "Unbiased for what!!"
July 9, 2025 at 10:21 AM
timpmorris.bsky.social
New post: “Marginal” and “conditional” are relative descriptions of an estimand
Foreground text says “Marginal” and “conditional” are relative descriptions of an estimand In the background is a smokey mollusc
July 7, 2025 at 3:10 PM
timpmorris.bsky.social
“UKRI to scale-up ‘radical’ change to peer review”
[after screening Hunger Games and Battle Royale at an away day]
www.researchprofessionalnews.com/rr-news-uk-r...
A poster for The Hunger Games but with the word Hunger changed to Funder
July 3, 2025 at 1:27 PM
timpmorris.bsky.social
We’re all thinking it all the time
June 18, 2025 at 8:26 AM
timpmorris.bsky.social
Should have worn a suit today but then I didn’t know when I woke up that I’d find an apple big enough to obscure my face!
Doing the pose like The Son of Man painting
June 8, 2025 at 5:08 PM
timpmorris.bsky.social
Richard Don-Don; pleased to meet you 🤝

A while ago me and the kids made up a bunch of names we found funny and they’ve become alter-egos for when we don’t want to give our real names.

The kids go by Humanity The Puppy and William Bottoms.
Screenshot of my coffee order with my alter-ego
June 7, 2025 at 9:20 AM
timpmorris.bsky.social
Here you go. The claim about water-then-espresso, and crema, from James Hoffmann’s coffee book (he’s a good follow in Instagram btw).
Some people claim that you should never add very hot water to an espresso, and always brew the espresso on top of the hot water. I don't think it makes a great deal of difference, I just find the resulting coffee is cleaner and looks better. The one disadvantage of diluting espresso is that you increase the perceived bitterness slightly. For that reason, as soon as you finish brewing the americano, I would recommend scooping the crema off the top of the drink and discarding it. Crema is delightful to look at, but there are many tiny pieces of ground coffee trapped in the foam so the crema contributes additional bitterness to the drink. Removing the crema before stirring and drinking definitely improves the flavour of an americano. (I would also recommend tasting an espresso after you remove the crema - the difference in flavour is dramatic. While I actually prefer the taste of an espresso without crema, I don't want the extra work and am happy enough to enjoy it as it is. With an americano, however, I really do think the extra work is worthwhile.)
June 2, 2025 at 10:38 AM
timpmorris.bsky.social
Wait what?

www.jclinepi.com/article/S089...
Screenshot of abstract from “GRADE guidelines 6. Rating the quality of evidence—imprecision” https://www.jclinepi.com/article/S0895-4356(11)00206-X/fulltext with highlighting on “An exception to this rule occurs when an effect is large, and consideration of CIs alone suggests a robust effect, but the total sample size is not large and the number of events is small. Under these circumstances, one should consider rating down for imprecision.”
May 22, 2025 at 4:15 PM
timpmorris.bsky.social
As an non-psych methodologist, I predict the results of a review of existing studies
Bar chart showing the number of studies targeting a relevant, useful estimand using defensible methods of design & analysis: zero.
May 19, 2025 at 11:58 AM
timpmorris.bsky.social
No shit, Sherlock
Screenshot from a website’s twitter scroller: ‘Something went wrong with the twitter.’
May 19, 2025 at 11:35 AM
timpmorris.bsky.social
Ever wondered about the wonder of zip plots? Here’s an educational post describing how to read them.

open.substack.com/pub/tpmorris...
Picture shows title of post ‘How to read a zip plot’ in front of a greyed-out image of the zip plot used in the post.
May 16, 2025 at 1:36 PM