Tata Institute of Fundamental Research
@tifr.res.in
TIFR is a research institute & Deemed University for Natural Sciences, Mathematics, Computer Science & Science Education, under the Dept of Atomic Energy, Govt of India.
Website https://main.tifr.res.in/ | Science Communication https://tifr.res.in/scicomm
Website https://main.tifr.res.in/ | Science Communication https://tifr.res.in/scicomm
Download & Read 'Tuning Mental Frameworks' here: www.hbcse.tifr.res.in/people/facul...
www.hbcse.tifr.res.in
November 11, 2025 at 9:57 AM
Download & Read 'Tuning Mental Frameworks' here: www.hbcse.tifr.res.in/people/facul...
4/ These findings help us better understand what might go wrong in conditions like Alzheimer’s or Parkinson’s, where transport and cargo-sorting in neurons are disrupted. #Neurodegeneration #MolecularMotors
October 29, 2025 at 9:24 AM
4/ These findings help us better understand what might go wrong in conditions like Alzheimer’s or Parkinson’s, where transport and cargo-sorting in neurons are disrupted. #Neurodegeneration #MolecularMotors
3/ Amal found that the BORC complex acts like a molecular logistics manager, helping motor proteins UNC-104 & UNC-116 direct synaptic and lysosomal proteins into separate compartments. This ensures smooth communication between neurons. #CellBiology
October 29, 2025 at 9:24 AM
3/ Amal found that the BORC complex acts like a molecular logistics manager, helping motor proteins UNC-104 & UNC-116 direct synaptic and lysosomal proteins into separate compartments. This ensures smooth communication between neurons. #CellBiology
2/ Synaptic vesicles contain tiny chemical messengers in neurons called neurotransmitters. Before they reach their destination, they’re packed & sorted at the cell body—like loading docks before long highway trips. Amal’s thesis zoomed in on how this process works.
October 29, 2025 at 9:24 AM
2/ Synaptic vesicles contain tiny chemical messengers in neurons called neurotransmitters. Before they reach their destination, they’re packed & sorted at the cell body—like loading docks before long highway trips. Amal’s thesis zoomed in on how this process works.
Read the preprint here: www.biorxiv.org/content/10.1...
BORC segregates synaptic vesicle and lysosomal proteins through motors UNC-104/KIF1A and UNC-116/KIF5
While synaptic vesicle proteins (SVPs) and lysosomal proteins can be present together in axons, the origin of these compartments is unclear. These SV-lysosomes are however thought to segregate further...
www.biorxiv.org
October 29, 2025 at 8:50 AM
Read the preprint here: www.biorxiv.org/content/10.1...