Reposted by Jeff Nurdin
In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:
January 17, 2025 at 6:43 PM
In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:
Talking on the phone with a friend living in Louisiana.
Her: "It might snow next Tuesday"
Me: "Yeah. It's gonna be -2 and -9 on Monday and Tuesday
Her: "How cold is that in Fahrenheit?"
Me: "That is Fahrenheit"
Her: "It might snow next Tuesday"
Me: "Yeah. It's gonna be -2 and -9 on Monday and Tuesday
Her: "How cold is that in Fahrenheit?"
Me: "That is Fahrenheit"
January 17, 2025 at 3:06 PM
Talking on the phone with a friend living in Louisiana.
Her: "It might snow next Tuesday"
Me: "Yeah. It's gonna be -2 and -9 on Monday and Tuesday
Her: "How cold is that in Fahrenheit?"
Me: "That is Fahrenheit"
Her: "It might snow next Tuesday"
Me: "Yeah. It's gonna be -2 and -9 on Monday and Tuesday
Her: "How cold is that in Fahrenheit?"
Me: "That is Fahrenheit"
Reposted by Jeff Nurdin
Our work on cellular RNA interactions with MAVS that promote antiviral signaling is finally live. So grateful to our indispensable collaborators as well as reviewers who helped to strengthen our work. #RNA #innateimmunity #virology
@ramlabuw.bsky.social
www.science.org/doi/10.1126/...
@ramlabuw.bsky.social
www.science.org/doi/10.1126/...
Cellular RNA interacts with MAVS to promote antiviral signaling
Antiviral signaling downstream of RIG-I–like receptors (RLRs) proceeds through a multi-protein complex organized around the adaptor protein mitochondrial antiviral signaling protein (MAVS). Protein co...
www.science.org
December 19, 2024 at 8:13 PM
Our work on cellular RNA interactions with MAVS that promote antiviral signaling is finally live. So grateful to our indispensable collaborators as well as reviewers who helped to strengthen our work. #RNA #innateimmunity #virology
@ramlabuw.bsky.social
www.science.org/doi/10.1126/...
@ramlabuw.bsky.social
www.science.org/doi/10.1126/...
Reposted by Jeff Nurdin
📣 Postdoc position available in my group at Pitt to study how Klebsiella controls its cell surface and develop new projects. themikelab.com
Read more and apply here by Jan 12:
cfopitt.taleo.net/careersectio...
Reposts are appreciated!
#klebclub
#newPI
Read more and apply here by Jan 12:
cfopitt.taleo.net/careersectio...
Reposts are appreciated!
#klebclub
#newPI
December 17, 2024 at 4:39 PM
📣 Postdoc position available in my group at Pitt to study how Klebsiella controls its cell surface and develop new projects. themikelab.com
Read more and apply here by Jan 12:
cfopitt.taleo.net/careersectio...
Reposts are appreciated!
#klebclub
#newPI
Read more and apply here by Jan 12:
cfopitt.taleo.net/careersectio...
Reposts are appreciated!
#klebclub
#newPI
Reposted by Jeff Nurdin
I’m proud to join more than 30 colleagues today in sharing our analysis of potential risks from “mirror life”. We summarize our findings in a @science.org article, and in greater detail in a 300pg technical report:
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
December 12, 2024 at 7:05 PM
I’m proud to join more than 30 colleagues today in sharing our analysis of potential risks from “mirror life”. We summarize our findings in a @science.org article, and in greater detail in a 300pg technical report:
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
Reposted by Jeff Nurdin
CANADIAN Version of this series would have been boring. Man gets cancer... Man goes to Dr. because they have universal healthcare. The End.
December 8, 2024 at 9:13 AM
CANADIAN Version of this series would have been boring. Man gets cancer... Man goes to Dr. because they have universal healthcare. The End.
Reposted by Jeff Nurdin
Receptor switching is one of the key steps in adaptation of animal influenza viruses to humans. Studies shows that is requires only a single mutation to do that. The widespread circulation of AI in cattle is playing with fire. www.science.org/doi/10.1126/...
A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors
In 2024, several human infections with highly pathogenic clade 2.3.4.4b bovine influenza H5N1 viruses in the United States raised concerns about their capability for bovine-to-human or even human-to-h...
www.science.org
December 6, 2024 at 7:08 AM
Receptor switching is one of the key steps in adaptation of animal influenza viruses to humans. Studies shows that is requires only a single mutation to do that. The widespread circulation of AI in cattle is playing with fire. www.science.org/doi/10.1126/...
It's kinda a slap in the face when we're told that some people might be uncomfortable if we're bringing our same sex spouse to a departmental holiday party. DEI is merely just a slogan, I guess
November 16, 2023 at 3:33 PM
It's kinda a slap in the face when we're told that some people might be uncomfortable if we're bringing our same sex spouse to a departmental holiday party. DEI is merely just a slogan, I guess
Glad that BlueSky is slowly but surely getting busier
October 23, 2023 at 1:00 AM
Glad that BlueSky is slowly but surely getting busier
Reposted by Jeff Nurdin
Viruses use RNA decoys to thwart CRISPR defences
www.nature.com/articles/d41...
Related paper:
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Related paper:
www.nature.com/articles/s41...
Viruses use RNA decoys to thwart CRISPR defences
Bacteria and archaea are microorganisms that often use RNA-guided defences called CRISPR to destroy the genomes of viruses that infect them. It now emerges that viruses make RNAs that act as mimics to...
www.nature.com
October 19, 2023 at 1:31 PM
Viruses use RNA decoys to thwart CRISPR defences
www.nature.com/articles/d41...
Related paper:
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Related paper:
www.nature.com/articles/s41...
Interesting article www.nature.com/articles/s41...
Clinical trial links oncolytic immunoactivation to survival in glioblastoma - Nature
Treatment with the oncolytic herpes virus CAN-3110 is associated with improved survival responses in patients with recurrent glioblastoma, particularly in individuals who are seropositive for HSV...
www.nature.com
October 18, 2023 at 9:17 PM
Interesting article www.nature.com/articles/s41...
Reposted by Jeff Nurdin
Getting around to this paper in Journal of Virology and its a banger. Prenatal exposure to RSV season in the *third trimester* significantly reduces a child's risk of RSV-LRI in first year. And it seems to be a fetal IFN response, not maternal antibodies.
ViroSky ☣️
journals.asm.org/doi/10.1128/...
ViroSky ☣️
journals.asm.org/doi/10.1128/...
Prenatal exposure to RSV season influences first-year risk of RSV lower respiratory illness and RSV-...
Our study found that duration of third trimester exposure to RSV season related inversely
to subsequent risk of postnatal RSV-LRI in the first year, thus implicating this exposure
as an important fact...
journals.asm.org
October 17, 2023 at 10:03 PM
Getting around to this paper in Journal of Virology and its a banger. Prenatal exposure to RSV season in the *third trimester* significantly reduces a child's risk of RSV-LRI in first year. And it seems to be a fetal IFN response, not maternal antibodies.
ViroSky ☣️
journals.asm.org/doi/10.1128/...
ViroSky ☣️
journals.asm.org/doi/10.1128/...
The other place is getting worse. I avoided opening it now. I'm scared
October 17, 2023 at 12:58 PM
The other place is getting worse. I avoided opening it now. I'm scared
"Ma! Your son's gonna present here!"
Just kidding. She doesn't even understand what I'm doing here. Some kind of teaching, she thought. Really honored for my work to be chosen among other presenters from the top universities. Find out here for more info voices.uchicago.edu/bsddiversity...
Just kidding. She doesn't even understand what I'm doing here. Some kind of teaching, she thought. Really honored for my work to be chosen among other presenters from the top universities. Find out here for more info voices.uchicago.edu/bsddiversity...
October 10, 2023 at 11:00 PM
"Ma! Your son's gonna present here!"
Just kidding. She doesn't even understand what I'm doing here. Some kind of teaching, she thought. Really honored for my work to be chosen among other presenters from the top universities. Find out here for more info voices.uchicago.edu/bsddiversity...
Just kidding. She doesn't even understand what I'm doing here. Some kind of teaching, she thought. Really honored for my work to be chosen among other presenters from the top universities. Find out here for more info voices.uchicago.edu/bsddiversity...
Reposted by Jeff Nurdin
PARENTS BEWARE! Your child’s innocent trick or treat bag may contain quantum dots.
October 5, 2023 at 2:21 AM
PARENTS BEWARE! Your child’s innocent trick or treat bag may contain quantum dots.
Reposted by Jeff Nurdin
Very cool CryoEM paper of HKU1 S1 conformation change upon binding to sialoglycan receptor (the Spike NTD binds 9OAc Sialic Acid).
ViroSky ☣️
www.nature.com/articles/s41...
ViroSky ☣️
www.nature.com/articles/s41...
October 4, 2023 at 8:22 PM
Very cool CryoEM paper of HKU1 S1 conformation change upon binding to sialoglycan receptor (the Spike NTD binds 9OAc Sialic Acid).
ViroSky ☣️
www.nature.com/articles/s41...
ViroSky ☣️
www.nature.com/articles/s41...
Interesting article about assembly theory. Some people already digging into this while the others convinced that the emergency alert will turn COVID vaccine recipient into a zombie www.nature.com/articles/s41...
October 5, 2023 at 3:40 AM
Interesting article about assembly theory. Some people already digging into this while the others convinced that the emergency alert will turn COVID vaccine recipient into a zombie www.nature.com/articles/s41...
Eight percentile and 12 for new PIs?
September 29, 2023 at 11:10 PM
Eight percentile and 12 for new PIs?