Teemu Karjalainen
teemuvkarjalainen.bsky.social
Teemu Karjalainen
@teemuvkarjalainen.bsky.social
Hand surgeon and clinical scientist focussing on msk efficacy/effectiveness research.

Endurance sports junkie on free time
Somehow I wasn't too surprised to learn this is from am j sports med.

Have a look at this conclusion. (the discussion of the mechanism of effect is priceless)

pubmed.ncbi.nlm.nih.gov/27566242/
A Prospective, Single-Blind, Placebo-Controlled Trial of Bone Marrow Aspirate Concentrate for Knee Osteoarthritis - PubMed
Early results show that BMAC is safe to use and is a reliable and viable cellular product. Study patients experienced a similar relief of pain in both BMAC- and saline-treated arthritic knees. Further...
pubmed.ncbi.nlm.nih.gov
April 17, 2025 at 2:07 PM
Reposted by Teemu Karjalainen
You regular reminder that millions has been spent on research into therapeutic benefits of insert placebos, to no avail, mainly because scientists who should know better still believe that the rooster crowing must make the sun rise.

zenodo.org/records/3886...
Nonplussed by placebos: A response to Colloca and Barsky (2020)
In a recent review published in the New England Journal of Medicine (Placebo and Nocebo Effects), Colloca and Barsky concluded that “Placebo and nocebo effects are powerful, pervasive, and common in c...
zenodo.org
April 17, 2025 at 1:10 PM
You wouldn't promise such things even in your grant application (which are always overly optimistic).

But nevertheless he said by September we will know. Not sure what knowing means here
April 11, 2025 at 7:19 AM
Never got such a lot of feed back on any of my work. Even personal emails and ofc letter to editor from a panel of keen&offended arthroscopists.

Letter and response better fun than the paper itself
April 7, 2025 at 9:48 AM
What happens if we don't operate people with failed nonoperative treatment?

They nevertheless recover.

Ineffective surgery does not magically become effective if other treatments are ineffective.
April 4, 2025 at 6:52 PM
Rydmanin päiväkirjassa?
April 3, 2025 at 2:32 PM