Therese Cronin
@tcronin.bsky.social
Gene therapy for neuroinflammation and retinal disorders at Inserm and Nantes Université. Editing genes with caution. 🇮🇪 in Paris
Reposted by Therese Cronin
This ‘fundamental’ study uncovers how directing pyruvate into mitochondria can shrink cells by shifting their metabolism away from building amino acids and proteins.
buff.ly/hFHjKy9
buff.ly/hFHjKy9
December 8, 2025 at 11:28 PM
This ‘fundamental’ study uncovers how directing pyruvate into mitochondria can shrink cells by shifting their metabolism away from building amino acids and proteins.
buff.ly/hFHjKy9
buff.ly/hFHjKy9
Reposted by Therese Cronin
My dad abhors any negative comments about immigrants. Asked him recently why he’s so strong on it: ‘Because we’re always happy to take the rich and clever ones. Which means it’s not about disliking immigrants. It’s about disliking the poor and vulnerable. And that’s a bad human instinct.’
December 7, 2025 at 8:31 AM
My dad abhors any negative comments about immigrants. Asked him recently why he’s so strong on it: ‘Because we’re always happy to take the rich and clever ones. Which means it’s not about disliking immigrants. It’s about disliking the poor and vulnerable. And that’s a bad human instinct.’
Reposted by Therese Cronin
December 5, 2025 at 10:06 PM
Well written, well-researched critic of the Irish Times Op-Ed by Collison - should make people enthusiastic about Collisons message (like me) rethink it.
Often too little room in the Abundance agendas for environmental policies.
Often too little room in the Abundance agendas for environmental policies.
I’ve written something on John Collison’s Op-Ed and environmental democracy
Next time you’re out in Dublin, check if you’re being “socially de-risked” by a friendly face from his think-tank
elajucd.com/2025/11/21/o...
Next time you’re out in Dublin, check if you’re being “socially de-risked” by a friendly face from his think-tank
elajucd.com/2025/11/21/o...
On Environmental Democracy and the Collisons’ “Abundance-Verse”
Andrew Jackson 21 November 2025 I. Introduction A clamour of praise greeted John Collison’s “how to get Ireland moving” Op-Ed following its publication in the Irish Times on 25th October: the Irish…
elajucd.com
November 22, 2025 at 4:43 PM
Well written, well-researched critic of the Irish Times Op-Ed by Collison - should make people enthusiastic about Collisons message (like me) rethink it.
Often too little room in the Abundance agendas for environmental policies.
Often too little room in the Abundance agendas for environmental policies.
Reposted by Therese Cronin
My latest article for @forbes.com has just gone live 🧪👩🔬⚛️ www.forbes.com/sites/laurie...
Cities Are Expanding Uphill, Threatening Global Biodiversity
New study reveals cities expanding into hillsides threaten 70% of endangered species worldwide. Learn how urban sprawl impacts biodiversity hotspots globally.
www.forbes.com
November 21, 2025 at 7:58 PM
My latest article for @forbes.com has just gone live 🧪👩🔬⚛️ www.forbes.com/sites/laurie...
Reposted by Therese Cronin
“I had hemophilia for nearly five decades. I went to Philadelphia and had a 45-minute infusion, and my hemophilia was gone.”
Genes-> Medicine
nature.com/articles/s41...
Genes-> Medicine
nature.com/articles/s41...
November 21, 2025 at 9:45 PM
“I had hemophilia for nearly five decades. I went to Philadelphia and had a 45-minute infusion, and my hemophilia was gone.”
Genes-> Medicine
nature.com/articles/s41...
Genes-> Medicine
nature.com/articles/s41...
Reposted by Therese Cronin
I will never forget having to edit Jamal’s final, posthumous piece for the Washington Post, after he was murdered.
He was calling for free expression in the Arab world. You can read it here :
www.washingtonpost.com/opinions/glo...
He was calling for free expression in the Arab world. You can read it here :
www.washingtonpost.com/opinions/glo...
Opinion | Jamal Khashoggi: What the Arab world needs most is free expression
The Arab world needs a modern version of the old transnational media so citizens can be informed about global events.
www.washingtonpost.com
November 18, 2025 at 6:48 PM
I will never forget having to edit Jamal’s final, posthumous piece for the Washington Post, after he was murdered.
He was calling for free expression in the Arab world. You can read it here :
www.washingtonpost.com/opinions/glo...
He was calling for free expression in the Arab world. You can read it here :
www.washingtonpost.com/opinions/glo...
Reposted by Therese Cronin
Excellent work @victorcalbiagueg.bsky.social !!!
In this #TopicalReview, Victor Calbiague-Garcia of sorbonne-universite.fr et al. review current knowledge of #amacrine cells & discuss how emerging approaches are advancing our understanding of their function 👁️ 🐁
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 17, 2025 at 3:55 PM
Excellent work @victorcalbiagueg.bsky.social !!!
Reposted by Therese Cronin
Axonal pathfinding of zebrafish retinal ganglion cells forms the optic nerve. Credit to Dr. Matthew Bostock @houartlab.bsky.social. #ZebrafishZunday 🧪
November 16, 2025 at 8:30 PM
Axonal pathfinding of zebrafish retinal ganglion cells forms the optic nerve. Credit to Dr. Matthew Bostock @houartlab.bsky.social. #ZebrafishZunday 🧪
I did not even know that Sharon Begley died. I loved her articles.
Sure hope she got an obit worthy of someone who did the grit and didn't rely on lazy intuitions and over-confidence.
Sure hope she got an obit worthy of someone who did the grit and didn't rely on lazy intuitions and over-confidence.
A Sharon Begley byline, almost 5 years after her death.
Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written."
Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating.
🧪🧬🧫
Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written."
Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating.
🧪🧬🧫
James Watson, dead at 97, was a scientific legend and a pariah among his peers
James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.
www.statnews.com
November 10, 2025 at 2:00 PM
I did not even know that Sharon Begley died. I loved her articles.
Sure hope she got an obit worthy of someone who did the grit and didn't rely on lazy intuitions and over-confidence.
Sure hope she got an obit worthy of someone who did the grit and didn't rely on lazy intuitions and over-confidence.
Reposted by Therese Cronin
We are delighted to celebrate Science Week Ireland, especially to mark 30 years of this national celebration of curiosity, discovery, and public engagement with science.
@researchireland.ie
@norfireland.bsky.social
#scienceweek #scienceweekireland #publicengagement #openresearch #ThenTodayTomorrow
@researchireland.ie
@norfireland.bsky.social
#scienceweek #scienceweekireland #publicengagement #openresearch #ThenTodayTomorrow
November 10, 2025 at 1:10 PM
We are delighted to celebrate Science Week Ireland, especially to mark 30 years of this national celebration of curiosity, discovery, and public engagement with science.
@researchireland.ie
@norfireland.bsky.social
#scienceweek #scienceweekireland #publicengagement #openresearch #ThenTodayTomorrow
@researchireland.ie
@norfireland.bsky.social
#scienceweek #scienceweekireland #publicengagement #openresearch #ThenTodayTomorrow
Reposted by Therese Cronin
Oh dear. More worries about the consequences of CRISPR. The basic step - cutting both strands of DNA, which are then repaired, is not anodyne and has lasting effects.
Repair of DNA double-strand breaks leaves heritable impairment to genome function
Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...
www.science.org
November 6, 2025 at 9:44 PM
Oh dear. More worries about the consequences of CRISPR. The basic step - cutting both strands of DNA, which are then repaired, is not anodyne and has lasting effects.
Reposted by Therese Cronin
*sigh* Now I have to read a 17 page memo since apparently others won't.
October 28, 2025 at 4:20 PM
*sigh* Now I have to read a 17 page memo since apparently others won't.
Reposted by Therese Cronin
When #HHMIJanelia released the #Drosophila hemibrain in 2020, rendering all cell types at once with full shading/shadows was too hard, so the video showed them region by region. Technology has since advanced, and I went back and rendered them all together. I like how it shows the internal structure.
October 27, 2025 at 8:16 AM
When #HHMIJanelia released the #Drosophila hemibrain in 2020, rendering all cell types at once with full shading/shadows was too hard, so the video showed them region by region. Technology has since advanced, and I went back and rendered them all together. I like how it shows the internal structure.
Some good points in John Collisons article on why a country as rich and sparsely populated as Ireland has had failing infrastructure
www.irishtimes.com/life-style/p...
www.irishtimes.com/life-style/p...
John Collison of Stripe: Ireland is going backwards. Here’s how to get it moving
The Stripe co-founder looks at how the State can get out of the government-by-agency corner into which it has painted itself
www.irishtimes.com
October 27, 2025 at 9:22 AM
Some good points in John Collisons article on why a country as rich and sparsely populated as Ireland has had failing infrastructure
www.irishtimes.com/life-style/p...
www.irishtimes.com/life-style/p...
Finally. A big Yes in favour of synthetic biology to support conservation #IUCN
newsroom.wcs.org/News-Release...
newsroom.wcs.org/News-Release...
IUCN Members Choose Science and Ethics in Landmark Vote on Synthetic Biology
ABU DHABI, October 14 , 2025 — The Wildlife Conservation Society (WCS) today hailed the adoption of Motion 87, supporting the responsible, evidence-based use of synthetic biology, at the IUCN World Co...
newsroom.wcs.org
October 22, 2025 at 12:32 PM
Finally. A big Yes in favour of synthetic biology to support conservation #IUCN
newsroom.wcs.org/News-Release...
newsroom.wcs.org/News-Release...
Reposted by Therese Cronin
Un implant sous-rétinien restaure partiellement la vision de personnes atteintes de DMLA
Lire le communiqué : presse.inserm.fr/un-implant-s...
Lire le communiqué : presse.inserm.fr/un-implant-s...
Un implant sous-rétinien restaure partiellement la vision de personnes atteintes de DMLA - Salle de presse de l'Inserm
La dégénérescence maculaire liée à l’âge (DMLA) entraîne une perte progressive de vision chez un grand nombre de personnes âgées et aucun traitement n’est disponible pour la forme dite atrophique de c...
presse.inserm.fr
October 21, 2025 at 9:29 AM
Un implant sous-rétinien restaure partiellement la vision de personnes atteintes de DMLA
Lire le communiqué : presse.inserm.fr/un-implant-s...
Lire le communiqué : presse.inserm.fr/un-implant-s...
Reposted by Therese Cronin
Today is a good day. Lots of shade being cast in the speech announcing Nobel Peace Prize about growing authoritarianism
October 10, 2025 at 9:08 AM
Today is a good day. Lots of shade being cast in the speech announcing Nobel Peace Prize about growing authoritarianism
Reposted by Therese Cronin
Met Eireann warnings will presumably drop any time now. Still a way off and this is more uncertain than the usual being a post-tropical cyclone but if this ECMWF forecast verifies the norther half of the country is in for a rough old Friday afternoon and evening
September 30, 2025 at 10:28 AM
Met Eireann warnings will presumably drop any time now. Still a way off and this is more uncertain than the usual being a post-tropical cyclone but if this ECMWF forecast verifies the norther half of the country is in for a rough old Friday afternoon and evening
Reposted by Therese Cronin
Phenomenal. In my 10 year update of A Brief History, I make the point that in the first edition, not one disease had been successfully treated using gene therapy. Today that number is at least 7.
September 24, 2025 at 12:23 PM
Phenomenal. In my 10 year update of A Brief History, I make the point that in the first edition, not one disease had been successfully treated using gene therapy. Today that number is at least 7.
Reposted by Therese Cronin
David Baltimore, giant of molecular biology, has died.
Co-discoverer of reverse transcriptase at 32, Nobel Prize at 37, played a key role at the 1975 Asilomar comference.
David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87
www.nytimes.com
September 7, 2025 at 8:52 PM
David Baltimore, giant of molecular biology, has died.
I love this space. The almost-quiet, the little kids who've lost their shoes but found the biggest book they can carry, the ferry heading straight for you...
Ten years of DLR LexIcon in Dún Laoghaire: ‘People thought it was a vanity project and too much money’
"She says libraries are of the few non-religious buildings open to the community that people can just come into and sit down."
www.irishtimes.com/culture/book...
"She says libraries are of the few non-religious buildings open to the community that people can just come into and sit down."
www.irishtimes.com/culture/book...
Ten years of DLR LexIcon in Dún Laoghaire: ‘People thought it was a vanity project and too much money’
Award-winning but initially controversial building has become Ireland’s busiest public library
www.irishtimes.com
September 7, 2025 at 9:29 AM
I love this space. The almost-quiet, the little kids who've lost their shoes but found the biggest book they can carry, the ferry heading straight for you...
Reposted by Therese Cronin
Steve Shirley escaped the Holocaust as a child & went on to found one of the earliest software startups. The really impressive part? She employed women programmers who had been pushed out of the workforce after having kids, & allowed them flexible, family friendly, work from home jobs—in the 1960s!
@histoftech.bsky.social Am obit of interest that you might have seen already. Gift link:
www.nytimes.com/2025/08/20/b...
www.nytimes.com/2025/08/20/b...
Stephanie Shirley, Who Created a Tech World for Women, Dies at 91
www.nytimes.com
August 22, 2025 at 10:18 AM
Steve Shirley escaped the Holocaust as a child & went on to found one of the earliest software startups. The really impressive part? She employed women programmers who had been pushed out of the workforce after having kids, & allowed them flexible, family friendly, work from home jobs—in the 1960s!
Reposted by Therese Cronin
In summary, I hope the US regulation system does not allow embryo genome editing; I would far prefer that the regulation did not allow embryo selection on the basis of polygenic scores. Clearly these are decisions for the US regulation.
August 13, 2025 at 3:59 PM
In summary, I hope the US regulation system does not allow embryo genome editing; I would far prefer that the regulation did not allow embryo selection on the basis of polygenic scores. Clearly these are decisions for the US regulation.
Reposted by Therese Cronin
The excavator you see in the photo is mining out peat on a blanket bog under turbary rights which the state did *not* buy... in other words, more negotiation is required to stop this practice... and yes, that's a conifer plantation inside the Park boundary...
August 8, 2025 at 3:09 PM
The excavator you see in the photo is mining out peat on a blanket bog under turbary rights which the state did *not* buy... in other words, more negotiation is required to stop this practice... and yes, that's a conifer plantation inside the Park boundary...