Tanmay Bharat
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tbharat-lab.bsky.social
Tanmay Bharat
@tbharat-lab.bsky.social
MRC-LMB #cryoET #biofilms #S-layers #antibiotics
https://www2.mrc-lmb.cam.ac.uk/groups/bharat/
An Asgard archaeon with internal membrane compartments

Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!

www.biorxiv.org/content/10.1...
November 7, 2025 at 10:44 AM
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging

Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social

www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
August 31, 2025 at 6:44 PM
Building on our previous work:

Phage liquid crystalline droplets form occlusive sheaths that encapsulate and protect infectious rod-shaped bacteria

doi.org/10.1073/pnas...
July 29, 2025 at 9:35 AM
Targeted disruption of phage liquid crystalline droplets abolishes antibiotic tolerance of bacterial biofilms

led by @abultarafder.bsky.social

Great collaboration with @pearce-maths.bsky.social and @geiselbiofilm.bsky.social

www.biorxiv.org/cgi/content/...
July 29, 2025 at 9:35 AM
Structural and functional analysis of the Mycobacterium tuberculosis MmpS5L5 efflux pump presages a pathway to increased bedaquiline resistance

Exciting paper by Adam Fountain and Lalita Ramakrishnan. Cryo-ET by @janboehning.bsky.social

Congrats!

www.biorxiv.org/content/10.1...
June 25, 2025 at 11:00 AM
Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDAphi

Out in @pnas.org

Congrats @janboehning.bsky.social @abultarafder.bsky.social Miles Graham @mathieucoureuil.bsky.social
@mrclmb.bsky.social @hopitalnecker.bsky.social

www.pnas.org/doi/10.1073/...
June 23, 2025 at 10:26 AM
The mechanics of a continuous self-assembling surface-layer aids cell division in an archaeon

Tight collaboration with @buzzbaum.bsky.social, Sulfolobus cryo-ET from @idocaspy.bsky.social

www.biorxiv.org/content/10.1...
February 6, 2025 at 11:08 AM
Structure of the Pseudomonas aeruginosa PAO1 Type IV pilus
Finally out in PLOS Pathogens. Congrats Hannah Ochner and co-authors. @mrclmb.bsky.social

journals.plos.org/plospathogen...
December 16, 2024 at 3:53 PM