Tima Karginov
@takarginov.bsky.social
Immuno-RNA MD/PhD Student - Vella Lab - UConn Health |
UChicago TF/XC alum | President Hartbeat Track Club | Leaving the fly bottle of language
UChicago TF/XC alum | President Hartbeat Track Club | Leaving the fly bottle of language
Pinned
Tima Karginov
@takarginov.bsky.social
· Nov 10
Autoregulated splicing of TRA2β programs T cell fate in response to antigen-receptor stimulation
T cell receptor (TCR) sensitivity to peptide–major histocompatibility complex (MHC) dictates T cell fate. Canonical models of TCR sensitivity cannot be fully explained by transcriptional regulation. I...
www.science.org
Excited to be on to greener pastures... Just sharing some of our work from the last few years here to start!
www.science.org/doi/10.1126/...
www.nature.com/articles/s41...
www.science.org/doi/10.1126/...
www.nature.com/articles/s41...
Check out this awesome article by Andrew during his time in
Penghua Wang's lab on GLUT4's role in innate immunity - it was a privilege to get to watch this work go from idea to reality during our PhDs in our many "window chats" and contribute to the project!
Penghua Wang's lab on GLUT4's role in innate immunity - it was a privilege to get to watch this work go from idea to reality during our PhDs in our many "window chats" and contribute to the project!
November 20, 2024 at 10:16 PM
Check out this awesome article by Andrew during his time in
Penghua Wang's lab on GLUT4's role in innate immunity - it was a privilege to get to watch this work go from idea to reality during our PhDs in our many "window chats" and contribute to the project!
Penghua Wang's lab on GLUT4's role in innate immunity - it was a privilege to get to watch this work go from idea to reality during our PhDs in our many "window chats" and contribute to the project!
We were able to round up an awesome line up of speakers this year -- please come out and join us for the 2nd Sid Altman Memorial Symposium on January 17th!
Hey RNA enthusiasts 🎉
Start 2025 with us at the Sid Altman Memorial Symposium!
Join us on Jan 17 for 5 inspiring RNA researchers talks+ poster session.
📅 Register by Dec 13 to save your spot!
Let’s make learning about RNA a New Year’s resolution we can all get behind. Hope to see you there! 😄 #RNA
Start 2025 with us at the Sid Altman Memorial Symposium!
Join us on Jan 17 for 5 inspiring RNA researchers talks+ poster session.
📅 Register by Dec 13 to save your spot!
Let’s make learning about RNA a New Year’s resolution we can all get behind. Hope to see you there! 😄 #RNA
November 12, 2024 at 7:01 PM
We were able to round up an awesome line up of speakers this year -- please come out and join us for the 2nd Sid Altman Memorial Symposium on January 17th!
Reposted by Tima Karginov
New preprint 📣📣
Together with Monika Wolker's lab
@sanquin Amsterdam, we optimized a smFISH protocol for T cells. We measured cytokines IFNG/TNF expression and localization during T cell activation and optimized an imaging pipeline for quantification.
www.biorxiv.org/content/10.1...
Together with Monika Wolker's lab
@sanquin Amsterdam, we optimized a smFISH protocol for T cells. We measured cytokines IFNG/TNF expression and localization during T cell activation and optimized an imaging pipeline for quantification.
www.biorxiv.org/content/10.1...
Single molecule imaging of transcription dynamics, RNA localization and fate in T cells
T cells are critical effector cells against infections and malignancies. To achieve this, they produce pro-inflammatory cytokines, including IFN-gamma and TNF. Cytokine production is a tightly regulat...
www.biorxiv.org
November 12, 2024 at 1:24 PM
New preprint 📣📣
Together with Monika Wolker's lab
@sanquin Amsterdam, we optimized a smFISH protocol for T cells. We measured cytokines IFNG/TNF expression and localization during T cell activation and optimized an imaging pipeline for quantification.
www.biorxiv.org/content/10.1...
Together with Monika Wolker's lab
@sanquin Amsterdam, we optimized a smFISH protocol for T cells. We measured cytokines IFNG/TNF expression and localization during T cell activation and optimized an imaging pipeline for quantification.
www.biorxiv.org/content/10.1...
Excited to be on to greener pastures... Just sharing some of our work from the last few years here to start!
www.science.org/doi/10.1126/...
www.nature.com/articles/s41...
www.science.org/doi/10.1126/...
www.nature.com/articles/s41...
Autoregulated splicing of TRA2β programs T cell fate in response to antigen-receptor stimulation
T cell receptor (TCR) sensitivity to peptide–major histocompatibility complex (MHC) dictates T cell fate. Canonical models of TCR sensitivity cannot be fully explained by transcriptional regulation. I...
www.science.org
November 10, 2024 at 7:48 PM
Excited to be on to greener pastures... Just sharing some of our work from the last few years here to start!
www.science.org/doi/10.1126/...
www.nature.com/articles/s41...
www.science.org/doi/10.1126/...
www.nature.com/articles/s41...