Sander Wuyts, PhD 🧬
@swuyts.bsky.social
Helping scientists find the epitope specificity of their T-cell receptors at @immunewatch.bsky.social (www.immunewatch.com)
Scientist on an entrepreneurial journey
PhD in bioinformatics and microbiology
Ex-Bork (EMBL) and Lebeer lab
Scientist on an entrepreneurial journey
PhD in bioinformatics and microbiology
Ex-Bork (EMBL) and Lebeer lab
Pinned
Why did I trade academia for a startup environment?
Because several scientist I worked with during my PhD convinced me of their mission:
They want to fully decode the T-cell repertoire.
I recently found an old slide that visualises this goal beautifully.
#ImmunoSky
1/5
Because several scientist I worked with during my PhD convinced me of their mission:
They want to fully decode the T-cell repertoire.
I recently found an old slide that visualises this goal beautifully.
#ImmunoSky
1/5
Crazy excited about Jack White being on tour again! He was just announced headlining Best Kept Secret festival in the NL 🥳
October 28, 2025 at 1:47 PM
Crazy excited about Jack White being on tour again! He was just announced headlining Best Kept Secret festival in the NL 🥳
Episode 3 of “The Repertoire Room” has just been released!
After 2 episodes with technology providers in the TCR sequencing space, I now wanted to have a conversation with someone that was really using these technologies to push innovative therapies to patients.
Enter: @armanaksoy.bsky.social
After 2 episodes with technology providers in the TCR sequencing space, I now wanted to have a conversation with someone that was really using these technologies to push innovative therapies to patients.
Enter: @armanaksoy.bsky.social
October 28, 2025 at 12:52 PM
Episode 3 of “The Repertoire Room” has just been released!
After 2 episodes with technology providers in the TCR sequencing space, I now wanted to have a conversation with someone that was really using these technologies to push innovative therapies to patients.
Enter: @armanaksoy.bsky.social
After 2 episodes with technology providers in the TCR sequencing space, I now wanted to have a conversation with someone that was really using these technologies to push innovative therapies to patients.
Enter: @armanaksoy.bsky.social
This might end up in the void, but is ESMO IO worth attending?
October 27, 2025 at 2:39 PM
This might end up in the void, but is ESMO IO worth attending?
If you asked me 10 years ago, I wouldn't have guessed that I would ever give a guest lecture on "Innovation and Entrepreneurship"
Talks about microbiology, sequencing technologies, gene editing technologies, fermentation or bioinformatics: yes. But Entrepreneurship, nah :)
Talks about microbiology, sequencing technologies, gene editing technologies, fermentation or bioinformatics: yes. But Entrepreneurship, nah :)
October 3, 2025 at 9:00 AM
If you asked me 10 years ago, I wouldn't have guessed that I would ever give a guest lecture on "Innovation and Entrepreneurship"
Talks about microbiology, sequencing technologies, gene editing technologies, fermentation or bioinformatics: yes. But Entrepreneurship, nah :)
Talks about microbiology, sequencing technologies, gene editing technologies, fermentation or bioinformatics: yes. But Entrepreneurship, nah :)
Reposted by Sander Wuyts, PhD 🧬
Tonight at a public meeting I clapped when everyone else was murmuring in fear and worry about the idea of reducing the number of lanes on a road in order to accommodate wider sidewalks and bike lanes. Definitely an outlier.
I don’t hate cars. Like most North American males I was raised to think cars are cool, and as a design nerd, few objects are more eye-catching.
I hate surrendering our streets, our cities and our lives to them.
Car dependence isn’t freedom.
Great cartoon by @robcowan.bsky.social #CarDependency
I hate surrendering our streets, our cities and our lives to them.
Car dependence isn’t freedom.
Great cartoon by @robcowan.bsky.social #CarDependency
October 2, 2025 at 3:56 AM
Tonight at a public meeting I clapped when everyone else was murmuring in fear and worry about the idea of reducing the number of lanes on a road in order to accommodate wider sidewalks and bike lanes. Definitely an outlier.
Always curious whether this new update will bring new insights for you!
We committed ourselves to push new TCR-epitope data to our database every quarter.
Last week we published a new version of ImmuneWatch DETECT with TCRs for 75 different epitopes, of which 49 were not yet in our database.
Many new HPV epitopes!
immunewatch.gitlab.io/detect-docs/...
Last week we published a new version of ImmuneWatch DETECT with TCRs for 75 different epitopes, of which 49 were not yet in our database.
Many new HPV epitopes!
immunewatch.gitlab.io/detect-docs/...
September 25, 2025 at 11:48 AM
Always curious whether this new update will bring new insights for you!
Episode 2 of my podcast, the Repertoire Room is live!
In this podcast I hope to have insightful conversations with people working on TCR sequencing and analysis.
Now I sat down with the developer of one of the most used tools in the field: MiXCR
www.immunewatch.com/news/podcast...
In this podcast I hope to have insightful conversations with people working on TCR sequencing and analysis.
Now I sat down with the developer of one of the most used tools in the field: MiXCR
www.immunewatch.com/news/podcast...
Podcast: The Repertoire Room - Episode 2 featuring Stanislav Poslavsky (MiLaboratories)
www.immunewatch.com
September 17, 2025 at 10:46 AM
Episode 2 of my podcast, the Repertoire Room is live!
In this podcast I hope to have insightful conversations with people working on TCR sequencing and analysis.
Now I sat down with the developer of one of the most used tools in the field: MiXCR
www.immunewatch.com/news/podcast...
In this podcast I hope to have insightful conversations with people working on TCR sequencing and analysis.
Now I sat down with the developer of one of the most used tools in the field: MiXCR
www.immunewatch.com/news/podcast...
Never thought I was going to post something like this on our Slack but after submitting some EU-grants it felt like the right thing to do 😂
September 16, 2025 at 12:54 PM
Never thought I was going to post something like this on our Slack but after submitting some EU-grants it felt like the right thing to do 😂
From now on, my reading stats and recaps will be incorrect for eternity.
September 15, 2025 at 8:01 PM
From now on, my reading stats and recaps will be incorrect for eternity.
Reposted by Sander Wuyts, PhD 🧬
We are looking for a postdoc to study single-cell transcriptional heterogeneity in the human skin microbiome.
We have a new protocol mostly developed, but need someone to see it through. Experience with protocol dev or RNAseq appreciated.
Funded by a new grant from MIT-HEALS.
We have a new protocol mostly developed, but need someone to see it through. Experience with protocol dev or RNAseq appreciated.
Funded by a new grant from MIT-HEALS.
September 12, 2025 at 4:49 PM
We are looking for a postdoc to study single-cell transcriptional heterogeneity in the human skin microbiome.
We have a new protocol mostly developed, but need someone to see it through. Experience with protocol dev or RNAseq appreciated.
Funded by a new grant from MIT-HEALS.
We have a new protocol mostly developed, but need someone to see it through. Experience with protocol dev or RNAseq appreciated.
Funded by a new grant from MIT-HEALS.
Reposted by Sander Wuyts, PhD 🧬
Het aantal verkeersdoden in een land en stad is een politieke keuze. Geen technische. Dit is oud nieuws en al heel lang bekend. Doe wat Helsinki en Oslo doen die al jarenlang nul verkeersdoden hebben. Bange politici weigeren de automobilist aan te pakken.
August 5, 2025 at 4:37 AM
Het aantal verkeersdoden in een land en stad is een politieke keuze. Geen technische. Dit is oud nieuws en al heel lang bekend. Doe wat Helsinki en Oslo doen die al jarenlang nul verkeersdoden hebben. Bange politici weigeren de automobilist aan te pakken.
Reposted by Sander Wuyts, PhD 🧬
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good!
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
AlphaFold - A practical guide
AlphaFold - A practical guide
www.ebi.ac.uk
July 21, 2025 at 3:33 PM
Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good!
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...
Reposted by Sander Wuyts, PhD 🧬
First day of #ATCR25 in Antwerp: done ☑️ 🤩
Picture of Antwerp city station
#immunology #TCRrepertoire #Tcells #research
Picture of Antwerp city station
#immunology #TCRrepertoire #Tcells #research
May 27, 2025 at 4:06 PM
First day of #ATCR25 in Antwerp: done ☑️ 🤩
Picture of Antwerp city station
#immunology #TCRrepertoire #Tcells #research
Picture of Antwerp city station
#immunology #TCRrepertoire #Tcells #research
Reposted by Sander Wuyts, PhD 🧬
#Abstract submission deadline for #ATCR2025 is this Friday!
We are again very grateful to have such a strong lineup of #Tcell-receptor experts joining us in Antwerp. Currently at 80% capacity so do not wait to register.
www.uantwerpen.be/atcr2025
We are again very grateful to have such a strong lineup of #Tcell-receptor experts joining us in Antwerp. Currently at 80% capacity so do not wait to register.
www.uantwerpen.be/atcr2025
April 14, 2025 at 11:52 AM
#Abstract submission deadline for #ATCR2025 is this Friday!
We are again very grateful to have such a strong lineup of #Tcell-receptor experts joining us in Antwerp. Currently at 80% capacity so do not wait to register.
www.uantwerpen.be/atcr2025
We are again very grateful to have such a strong lineup of #Tcell-receptor experts joining us in Antwerp. Currently at 80% capacity so do not wait to register.
www.uantwerpen.be/atcr2025
Extremely excited to see a glimpse of my previous career in microbiome research here at #AACR25 with a talk from the great @cibiocm.bsky.social!
Reminds me of my great research stay I did in his lab in Trento.
Reminds me of my great research stay I did in his lab in Trento.
April 26, 2025 at 11:03 PM
Extremely excited to see a glimpse of my previous career in microbiome research here at #AACR25 with a talk from the great @cibiocm.bsky.social!
Reminds me of my great research stay I did in his lab in Trento.
Reminds me of my great research stay I did in his lab in Trento.
After a windy bike ride next to the lake, I am completely ready for week 2 of my US trip.
Reach out if you want to talk bikes, I mean TCR repertoires, coming days here in Chicago at #AACR25
Reach out if you want to talk bikes, I mean TCR repertoires, coming days here in Chicago at #AACR25
April 26, 2025 at 10:23 PM
After a windy bike ride next to the lake, I am completely ready for week 2 of my US trip.
Reach out if you want to talk bikes, I mean TCR repertoires, coming days here in Chicago at #AACR25
Reach out if you want to talk bikes, I mean TCR repertoires, coming days here in Chicago at #AACR25
Reposted by Sander Wuyts, PhD 🧬
Analysing and annotating the specificity of TCR repertoires just became a lot easier.
Check out our joint webinar with @milaboratories.bsky.social on how to use ImmuneWatch DETECT within Platforma
m.youtube.com/watch?v=ECpA...
Check out our joint webinar with @milaboratories.bsky.social on how to use ImmuneWatch DETECT within Platforma
m.youtube.com/watch?v=ECpA...
Webinar: Annotate the specificity of your TCRs on Platforma
YouTube video by ImmuneWatch
m.youtube.com
April 25, 2025 at 12:01 PM
Analysing and annotating the specificity of TCR repertoires just became a lot easier.
Check out our joint webinar with @milaboratories.bsky.social on how to use ImmuneWatch DETECT within Platforma
m.youtube.com/watch?v=ECpA...
Check out our joint webinar with @milaboratories.bsky.social on how to use ImmuneWatch DETECT within Platforma
m.youtube.com/watch?v=ECpA...
Washington I am here! 🇺🇸
Happy to connect here at The World Vaccine Congress and American Association for Cancer Research (Chicago) newt week.
Happy to connect here at The World Vaccine Congress and American Association for Cancer Research (Chicago) newt week.
April 22, 2025 at 8:55 PM
Washington I am here! 🇺🇸
Happy to connect here at The World Vaccine Congress and American Association for Cancer Research (Chicago) newt week.
Happy to connect here at The World Vaccine Congress and American Association for Cancer Research (Chicago) newt week.
** meme of guy that rubs his face **
April 18, 2025 at 12:54 PM
** meme of guy that rubs his face **
Are you attending ATCR 2025 (Antwerp TCR meeting)?
Already in town on Monday evening, 26 May?
Looking for a fun way to connect with fellow attendees?
Ever wanted to try a (non-alcoholic) Belgian beer in a real Belgian bar, but felt overwhelmed by the choices?
Then read on! 👇
Already in town on Monday evening, 26 May?
Looking for a fun way to connect with fellow attendees?
Ever wanted to try a (non-alcoholic) Belgian beer in a real Belgian bar, but felt overwhelmed by the choices?
Then read on! 👇
April 17, 2025 at 9:22 AM
Are you attending ATCR 2025 (Antwerp TCR meeting)?
Already in town on Monday evening, 26 May?
Looking for a fun way to connect with fellow attendees?
Ever wanted to try a (non-alcoholic) Belgian beer in a real Belgian bar, but felt overwhelmed by the choices?
Then read on! 👇
Already in town on Monday evening, 26 May?
Looking for a fun way to connect with fellow attendees?
Ever wanted to try a (non-alcoholic) Belgian beer in a real Belgian bar, but felt overwhelmed by the choices?
Then read on! 👇
Reposted by Sander Wuyts, PhD 🧬
The recent "Mal-ID" paper in Science diagnoses diseases from immune repertoires. But a powerful model like Mal-ID can learn differences between groups of immune repertoires that are unrelated to the diseases of interest. We explore these pitfalls in our eLetter response.
Disease diagnostics using machine learning of B cell and T cell receptor sequences
Clinical diagnosis typically incorporates physical examination, patient history, various laboratory tests, and imaging studies but makes limited use of the human immune system’s own record of antigen ...
www.science.org
March 19, 2025 at 10:35 PM
The recent "Mal-ID" paper in Science diagnoses diseases from immune repertoires. But a powerful model like Mal-ID can learn differences between groups of immune repertoires that are unrelated to the diseases of interest. We explore these pitfalls in our eLetter response.
I typed "ls" in my google search bar.
Good morning!
Good morning!
March 14, 2025 at 8:22 AM
I typed "ls" in my google search bar.
Good morning!
Good morning!
Happy to be Jake Baum's 🇦🇺 personal tour guide in Antwerp 🇧🇪 .
Enjoyed discussions on TCR-epitope predictions for malaria vaccine development in our CAPTIVATE EU Horizon project. We're using TCR sequencing to try & identify liver-stage T-cell antigens for a next-gen T-cell based malaria vaccine.
Enjoyed discussions on TCR-epitope predictions for malaria vaccine development in our CAPTIVATE EU Horizon project. We're using TCR sequencing to try & identify liver-stage T-cell antigens for a next-gen T-cell based malaria vaccine.
March 7, 2025 at 4:13 PM
Happy to be Jake Baum's 🇦🇺 personal tour guide in Antwerp 🇧🇪 .
Enjoyed discussions on TCR-epitope predictions for malaria vaccine development in our CAPTIVATE EU Horizon project. We're using TCR sequencing to try & identify liver-stage T-cell antigens for a next-gen T-cell based malaria vaccine.
Enjoyed discussions on TCR-epitope predictions for malaria vaccine development in our CAPTIVATE EU Horizon project. We're using TCR sequencing to try & identify liver-stage T-cell antigens for a next-gen T-cell based malaria vaccine.