Claudia Kasper
@suspigt.bsky.social
Geneticist, interested in nitrogen efficiency and welfare of farm animals, and phentoyping geek.
Reposted by Claudia Kasper
Happy to have been awarded an @erc.europa.eu grant RECOSEX to investigate molecular causes and evolutionary consequences of sex differences in recombination, using the wonderful Helgeland house sparrows as a model 🧬🐦 #ERCCoG 1/2
(Photos: Peter S. Ranke & Hamish Burnett)
(Photos: Peter S. Ranke & Hamish Burnett)
December 9, 2025 at 12:14 PM
Happy to have been awarded an @erc.europa.eu grant RECOSEX to investigate molecular causes and evolutionary consequences of sex differences in recombination, using the wonderful Helgeland house sparrows as a model 🧬🐦 #ERCCoG 1/2
(Photos: Peter S. Ranke & Hamish Burnett)
(Photos: Peter S. Ranke & Hamish Burnett)
Reposted by Claudia Kasper
Reposted by Claudia Kasper
Reposted by Claudia Kasper
Get bedder v0.1.8 and r𝗲𝗮𝗱 𝘁𝗵𝗲 𝗱𝗼𝗰𝘂𝗺𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻 here: github.com/quinlan-lab/...
We are looking for researchers to kick the tires, integrate bedder into their pipelines, and provide feedback on the Python functions, performance, and overall user experience! Please share and give us your feedback.
We are looking for researchers to kick the tires, integrate bedder into their pipelines, and provide feedback on the Python functions, performance, and overall user experience! Please share and give us your feedback.
Release Release v0.1.8 · quinlan-lab/bedder-rs
Changes in v0.1.8
Downloads
bedder-static-linux-x86_64: Static binary for Linux x86_64 (no dependencies required)
bedder-static-macos-x86_64-python3.13: macOS x86_64 binary built with Python 3.13
...
github.com
December 2, 2025 at 2:28 AM
Get bedder v0.1.8 and r𝗲𝗮𝗱 𝘁𝗵𝗲 𝗱𝗼𝗰𝘂𝗺𝗲𝗻𝘁𝗮𝘁𝗶𝗼𝗻 here: github.com/quinlan-lab/...
We are looking for researchers to kick the tires, integrate bedder into their pipelines, and provide feedback on the Python functions, performance, and overall user experience! Please share and give us your feedback.
We are looking for researchers to kick the tires, integrate bedder into their pipelines, and provide feedback on the Python functions, performance, and overall user experience! Please share and give us your feedback.
Reposted by Claudia Kasper
2. 𝗩𝗖𝗙 𝗜𝗻𝘁𝗲𝗴𝗿𝗮𝘁𝗶𝗼𝗻: For the first time, you can easily update VCF INFO fields based on interval overlaps, opening up new possibilities for variant annotation and processing.
Release Release v0.1.8 · quinlan-lab/bedder-rs
Changes in v0.1.8
Downloads
bedder-static-linux-x86_64: Static binary for Linux x86_64 (no dependencies required)
bedder-static-macos-x86_64-python3.13: macOS x86_64 binary built with Python 3.13
...
github.com
December 2, 2025 at 2:28 AM
2. 𝗩𝗖𝗙 𝗜𝗻𝘁𝗲𝗴𝗿𝗮𝘁𝗶𝗼𝗻: For the first time, you can easily update VCF INFO fields based on interval overlaps, opening up new possibilities for variant annotation and processing.
Reposted by Claudia Kasper
We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.
1/n
1/n
Intro to Bedder – The Quinlan Lab
quinlanlab.org
December 2, 2025 at 2:28 AM
Reposted by Claudia Kasper
Who is the brillant teacher who found a way to get kids to listen to Beethoven’s 5th—and like it! #AMomentofJoy
December 1, 2025 at 4:17 PM
Who is the brillant teacher who found a way to get kids to listen to Beethoven’s 5th—and like it! #AMomentofJoy
Reposted by Claudia Kasper
This is an astonishing story. Journal 'Science of the Total Environment' published *10,000 articles a year* Many were bogus.
Great summary of why our publication culture needs to be changed.
Great summary of why our publication culture needs to be changed.
Interesting investigation into a dodgy Elsevier journal -- with the additional nugget that the CEO of Elsevier's parent company made more than €15 million in total compensation last year.
english.elpais.com/science-tech...
english.elpais.com/science-tech...
The fall of a prolific science journal exposes the billion-dollar profits of scientific publishing
One of the 15 publications that put out the most studies globally has been expelled from the indexing system for irregularities. Its publisher, Elsevier, has a 38% profit margin that reached $1.5 bill...
english.elpais.com
November 29, 2025 at 10:21 AM
This is an astonishing story. Journal 'Science of the Total Environment' published *10,000 articles a year* Many were bogus.
Great summary of why our publication culture needs to be changed.
Great summary of why our publication culture needs to be changed.
Reposted by Claudia Kasper
Do you really understand p-values?
The p-value histogram can reveal a LOT about your data. Let's break it down using real examples.👇
The p-value histogram can reveal a LOT about your data. Let's break it down using real examples.👇
November 29, 2025 at 2:15 PM
Do you really understand p-values?
The p-value histogram can reveal a LOT about your data. Let's break it down using real examples.👇
The p-value histogram can reveal a LOT about your data. Let's break it down using real examples.👇
Reposted by Claudia Kasper
One for the heredity scolds: construct a multi-tissue GRM where people
are differentially related to themselves.
www.nature.com/articles/d41...
are differentially related to themselves.
www.nature.com/articles/d41...
We are all mosaics: vast genetic diversity found between cells in a single person
Technical advances allow researchers to trace the genetic changes that occur over time.
www.nature.com
November 28, 2025 at 10:16 AM
One for the heredity scolds: construct a multi-tissue GRM where people
are differentially related to themselves.
www.nature.com/articles/d41...
are differentially related to themselves.
www.nature.com/articles/d41...
Reposted by Claudia Kasper
November 24, 2025 at 11:46 PM
Reposted by Claudia Kasper
#OnThisDay in 1859, Charles Darwin's On the Origin of Species was first published.
Much of the original manuscript was used as scrap paper by Darwin's children. On the back of this painting of a house is an original manuscript page from Origin!
#CambridgeUniversityLibrary (DAR 185)
Much of the original manuscript was used as scrap paper by Darwin's children. On the back of this painting of a house is an original manuscript page from Origin!
#CambridgeUniversityLibrary (DAR 185)
November 24, 2025 at 11:26 AM
#OnThisDay in 1859, Charles Darwin's On the Origin of Species was first published.
Much of the original manuscript was used as scrap paper by Darwin's children. On the back of this painting of a house is an original manuscript page from Origin!
#CambridgeUniversityLibrary (DAR 185)
Much of the original manuscript was used as scrap paper by Darwin's children. On the back of this painting of a house is an original manuscript page from Origin!
#CambridgeUniversityLibrary (DAR 185)
Reposted by Claudia Kasper
🔴⚠️🌋🇪🇹After more than 10000 years,the 1st historical #eruption of #HayliGubbi #volcano has occurred in E. #Ethiopia, producing an eruptive column that reached more than 18km of height on Nov.23.⬇️Meteosat12 animation of RGB Ash product of the huge gas & ash plume moving eastward.
November 24, 2025 at 7:50 PM
🔴⚠️🌋🇪🇹After more than 10000 years,the 1st historical #eruption of #HayliGubbi #volcano has occurred in E. #Ethiopia, producing an eruptive column that reached more than 18km of height on Nov.23.⬇️Meteosat12 animation of RGB Ash product of the huge gas & ash plume moving eastward.
Reposted by Claudia Kasper
They grow bacteria on those hairy arms and then lick the bacteria off for a delightful snack, isn't that gross and cool?
November 24, 2025 at 7:12 PM
They grow bacteria on those hairy arms and then lick the bacteria off for a delightful snack, isn't that gross and cool?
Reposted by Claudia Kasper
hey everyone! i made a list of some useful starter packs (primarily biology/earth sciences with a few bonus things thrown in) to share with friends who have joined bsky in the last week and thought it may be useful for some people here too! 🌍🧪 #SciSky #BioSky docs.google.com/document/d/1...
Starter packs
BIOLOGY Ecology Macroecology https://go.bsky.app/GBn9pNZ Global ecology https://go.bsky.app/V6tN4cv Trait based ecology and evolution https://go.bsky.app/PThMXeX Invasion biology https://go.b...
docs.google.com
November 11, 2024 at 5:41 PM
hey everyone! i made a list of some useful starter packs (primarily biology/earth sciences with a few bonus things thrown in) to share with friends who have joined bsky in the last week and thought it may be useful for some people here too! 🌍🧪 #SciSky #BioSky docs.google.com/document/d/1...
Reposted by Claudia Kasper
“Every major epidemic we've had recently is a virus or from a family of viruses we’ve known about for some time prior &that has likely been circulating in some form for millennia….So if we got better at just diagnosing every case that came into the clinic, we would be prepared for every epidemic.”🧪🛟
November 23, 2025 at 1:20 AM
“Every major epidemic we've had recently is a virus or from a family of viruses we’ve known about for some time prior &that has likely been circulating in some form for millennia….So if we got better at just diagnosing every case that came into the clinic, we would be prepared for every epidemic.”🧪🛟
Reposted by Claudia Kasper
Two scientists who are fast friends, one Nigerian and one American, have won the MacArthur Foundation's 100&Change competition for their network to catch the next disease with pandemic potential.
$100 million prize goes to dynamic duo aiming to stop next pandemic before it starts
Two scientists who are fast friends, one Nigerian and one American, have won the MacArthur Foundation's 100&Change competition for their network to catch the next disease with pandemic potential.
n.pr
November 22, 2025 at 8:03 PM
Two scientists who are fast friends, one Nigerian and one American, have won the MacArthur Foundation's 100&Change competition for their network to catch the next disease with pandemic potential.
Reposted by Claudia Kasper
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
November 21, 2025 at 10:34 PM
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
Reposted by Claudia Kasper
The origin of 'pedigree'. This type of C12 figure (not a family tree but a way of calculating relatedness – the titles of various relatives have not been put in the circles) looked like a crane's foot, thought medieval folk. So 'pied de grue' and hence 'pedigree'. Source in alt.
November 18, 2025 at 9:44 AM
The origin of 'pedigree'. This type of C12 figure (not a family tree but a way of calculating relatedness – the titles of various relatives have not been put in the circles) looked like a crane's foot, thought medieval folk. So 'pied de grue' and hence 'pedigree'. Source in alt.
Reposted by Claudia Kasper
Photosynthetic sea slugs can decapitate themselves & regenerate whole body from the detached head (without the heart or guts), while the shed body do not regenerate. The process takes ~2-3 weeks. A new model for regeneration?
From: www.cell.com/current-biol...
From: www.cell.com/current-biol...
Extreme autotomy and whole-body regeneration in photosynthetic sea slugs
Autotomy, the voluntary shedding of a body part, is common among animals. Mitoh and
Yusa report an extreme case of autotomy with the shedding of the main body, including
the whole heart, and subsequen...
www.cell.com
November 22, 2025 at 4:00 PM
Photosynthetic sea slugs can decapitate themselves & regenerate whole body from the detached head (without the heart or guts), while the shed body do not regenerate. The process takes ~2-3 weeks. A new model for regeneration?
From: www.cell.com/current-biol...
From: www.cell.com/current-biol...
Reposted by Claudia Kasper
Team fish - we need your help! We are trying to build a database of all the fish chromosome-scale genomes where sex chromosomes have been identified. Have you build one or some? Do you know someone who has? Can you post the link in the comments? Please spread the word and repost! Thank you!
November 20, 2025 at 4:44 PM
Team fish - we need your help! We are trying to build a database of all the fish chromosome-scale genomes where sex chromosomes have been identified. Have you build one or some? Do you know someone who has? Can you post the link in the comments? Please spread the word and repost! Thank you!
Reposted by Claudia Kasper
Issue 22 of RDM Weekly is out! 📬
- FAIR Data Cheatsheet @w-u-r.bsky.social
- Open Research: Examples of Good Practice, and Resources Across Disciplines @ukrepro.bsky.social
- 3 Myths About Open Science That Just Won’t Die @syeducation.bsky.social
and more!
rdmweekly.substack.com/p/rdm-weekly...
- FAIR Data Cheatsheet @w-u-r.bsky.social
- Open Research: Examples of Good Practice, and Resources Across Disciplines @ukrepro.bsky.social
- 3 Myths About Open Science That Just Won’t Die @syeducation.bsky.social
and more!
rdmweekly.substack.com/p/rdm-weekly...
RDM Weekly - Issue 022
A weekly roundup of Research Data Management resources.
rdmweekly.substack.com
November 18, 2025 at 2:22 PM
Issue 22 of RDM Weekly is out! 📬
- FAIR Data Cheatsheet @w-u-r.bsky.social
- Open Research: Examples of Good Practice, and Resources Across Disciplines @ukrepro.bsky.social
- 3 Myths About Open Science That Just Won’t Die @syeducation.bsky.social
and more!
rdmweekly.substack.com/p/rdm-weekly...
- FAIR Data Cheatsheet @w-u-r.bsky.social
- Open Research: Examples of Good Practice, and Resources Across Disciplines @ukrepro.bsky.social
- 3 Myths About Open Science That Just Won’t Die @syeducation.bsky.social
and more!
rdmweekly.substack.com/p/rdm-weekly...
Reposted by Claudia Kasper
enjoyable little video on how wool gets graded and sorted
IG community_clothing and campaignforwool
IG community_clothing and campaignforwool
November 18, 2025 at 8:11 PM
enjoyable little video on how wool gets graded and sorted
IG community_clothing and campaignforwool
IG community_clothing and campaignforwool
Reposted by Claudia Kasper
1/ Concerns about low birth rates & below "replacement" fertility have been in the news a lot lately. But what does "replacement fertility" mean exactly?
(Throwback pic to that time I tried replacement fertility all in one go). jenndowd.substack.com/p/what-is-re... #demography #fertility
(Throwback pic to that time I tried replacement fertility all in one go). jenndowd.substack.com/p/what-is-re... #demography #fertility
November 18, 2025 at 3:46 PM
1/ Concerns about low birth rates & below "replacement" fertility have been in the news a lot lately. But what does "replacement fertility" mean exactly?
(Throwback pic to that time I tried replacement fertility all in one go). jenndowd.substack.com/p/what-is-re... #demography #fertility
(Throwback pic to that time I tried replacement fertility all in one go). jenndowd.substack.com/p/what-is-re... #demography #fertility
Reposted by Claudia Kasper
Is this wolf using a tool to get a seafood snack? Or does it not count, because the animal didn't construct the trap itself? @phiejacobs.bsky.social dives into that debate, plus more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪
November 18, 2025 at 7:48 PM
Is this wolf using a tool to get a seafood snack? Or does it not count, because the animal didn't construct the trap itself? @phiejacobs.bsky.social dives into that debate, plus more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪