stygimoloch
@stygimolochu.bsky.social
extant! poet, insufferable dittymaker, largely housebound charmer. collecting my ME/CFS research here w attempts at translating jargon into more accessible language
they/them, as relevant
they/them, as relevant
Last things!!
a. I say ME/CFS&LC bc there's a period where someone has LC but doesn't definitively have ME/CFS, & Covid-19 can grant bonus organ damage/etc.
b. classic issues with ME/CFS studies are that they tend to be tiny & also sometimes shit. We're all doing our best!
a. I say ME/CFS&LC bc there's a period where someone has LC but doesn't definitively have ME/CFS, & Covid-19 can grant bonus organ damage/etc.
b. classic issues with ME/CFS studies are that they tend to be tiny & also sometimes shit. We're all doing our best!
July 14, 2025 at 5:26 PM
Last things!!
a. I say ME/CFS&LC bc there's a period where someone has LC but doesn't definitively have ME/CFS, & Covid-19 can grant bonus organ damage/etc.
b. classic issues with ME/CFS studies are that they tend to be tiny & also sometimes shit. We're all doing our best!
a. I say ME/CFS&LC bc there's a period where someone has LC but doesn't definitively have ME/CFS, & Covid-19 can grant bonus organ damage/etc.
b. classic issues with ME/CFS studies are that they tend to be tiny & also sometimes shit. We're all doing our best!
Now that the problem has hopefully been established, I'll follow up with potential ameliorating options in another post! Obviously a lot of debt owed to the health rising article--I've known about the deformability issue for a while, but I hadn't thought about it for a hot minute.
July 14, 2025 at 4:34 PM
Now that the problem has hopefully been established, I'll follow up with potential ameliorating options in another post! Obviously a lot of debt owed to the health rising article--I've known about the deformability issue for a while, but I hadn't thought about it for a hot minute.
7 www.sciencedirect.com/science/article/pii/S1079979624000597
8 pmc.ncbi.nlm.nih.gov/articles/PMC...
9 pmc.ncbi.nlm.nih.gov/articles/PMC...
two links for RBC squish issues in ME/CFS&LC: pmc.ncbi.nlm.nih.gov/articles/PMC... Sakha et al. did 3 tiny studies
pmc.ncbi.nlm.nih.gov/articles/PMC...
8 pmc.ncbi.nlm.nih.gov/articles/PMC...
9 pmc.ncbi.nlm.nih.gov/articles/PMC...
two links for RBC squish issues in ME/CFS&LC: pmc.ncbi.nlm.nih.gov/articles/PMC... Sakha et al. did 3 tiny studies
pmc.ncbi.nlm.nih.gov/articles/PMC...
Erythrocyte deformability correlates with systemic inflammation
Recent evidence suggests that systemic conditions, particularly those associated with inflammation, can affect erythrocyte deformability in the absenc…
www.sciencedirect.com
July 14, 2025 at 4:26 PM
7 www.sciencedirect.com/science/article/pii/S1079979624000597
8 pmc.ncbi.nlm.nih.gov/articles/PMC...
9 pmc.ncbi.nlm.nih.gov/articles/PMC...
two links for RBC squish issues in ME/CFS&LC: pmc.ncbi.nlm.nih.gov/articles/PMC... Sakha et al. did 3 tiny studies
pmc.ncbi.nlm.nih.gov/articles/PMC...
8 pmc.ncbi.nlm.nih.gov/articles/PMC...
9 pmc.ncbi.nlm.nih.gov/articles/PMC...
two links for RBC squish issues in ME/CFS&LC: pmc.ncbi.nlm.nih.gov/articles/PMC... Sakha et al. did 3 tiny studies
pmc.ncbi.nlm.nih.gov/articles/PMC...
1 www.healthrising.org/blog/2025/06/28/blood-diffusion-chronic-fatigue-long-covid/
2 pmc.ncbi.nlm.nih.gov/articles/PMC...
3 pubmed.ncbi.nlm.nih.gov/19847056/
4 pubmed.ncbi.nlm.nih.gov/32417767/
5 www.cell.com/heliyon/fulltext/S2405-8440(24)17077-6
6 pubmed.ncbi.nlm.nih.gov/24246527/
2 pmc.ncbi.nlm.nih.gov/articles/PMC...
3 pubmed.ncbi.nlm.nih.gov/19847056/
4 pubmed.ncbi.nlm.nih.gov/32417767/
5 www.cell.com/heliyon/fulltext/S2405-8440(24)17077-6
6 pubmed.ncbi.nlm.nih.gov/24246527/
Are Barriers to Blood Diffusion Causing ME/CFS and Long COVID? The 2025 Charité International Conference Pt I - Health Rising
Conference findings suggest multiple barriers to blood flows could be causing chronic fatigue syndrome (ME/CFS) and long COVID.
www.healthrising.org
July 14, 2025 at 4:26 PM
Systemic inflammation₇ and inflammation caused by oxidative stress₈₊₉ are also associated with reduced RBC squish. Which! Classic ME/CFS&LC issues! I'm not even gonna half-assed cite for that!
July 14, 2025 at 4:26 PM
Systemic inflammation₇ and inflammation caused by oxidative stress₈₊₉ are also associated with reduced RBC squish. Which! Classic ME/CFS&LC issues! I'm not even gonna half-assed cite for that!
Oxygen doesn't get in, and carbon dioxide can't be taken away. This is a big fucking problem––even when "convective oxygen supply" is fine₂.
You see a lack of RBC squish factor in a variety of conditions, like say iron deficient anemia₃ or diabetes (type 1&2)₄₊₅, or sickle cell disease₆.
You see a lack of RBC squish factor in a variety of conditions, like say iron deficient anemia₃ or diabetes (type 1&2)₄₊₅, or sickle cell disease₆.
July 14, 2025 at 4:26 PM
Oxygen doesn't get in, and carbon dioxide can't be taken away. This is a big fucking problem––even when "convective oxygen supply" is fine₂.
You see a lack of RBC squish factor in a variety of conditions, like say iron deficient anemia₃ or diabetes (type 1&2)₄₊₅, or sickle cell disease₆.
You see a lack of RBC squish factor in a variety of conditions, like say iron deficient anemia₃ or diabetes (type 1&2)₄₊₅, or sickle cell disease₆.
Posting will be intermittent at best. I have no medical background, and none of this is medical advice. I don't anticipate anyone really seeing this, but if you do, and you have an interest in trying anything I talk about, please please talk to your doctor first. Interactions get complicated!
July 14, 2025 at 2:54 PM
Posting will be intermittent at best. I have no medical background, and none of this is medical advice. I don't anticipate anyone really seeing this, but if you do, and you have an interest in trying anything I talk about, please please talk to your doctor first. Interactions get complicated!
When I have the energy I focus on elements of various systems, and look into treatment options that exist.
I've had CFS/ME for a decade, so I'm not expecting a cure, but anything that can sustainably get me a few percentile points is a good thing. Plus, what a puzzle!
I've had CFS/ME for a decade, so I'm not expecting a cure, but anything that can sustainably get me a few percentile points is a good thing. Plus, what a puzzle!
July 14, 2025 at 2:51 PM
When I have the energy I focus on elements of various systems, and look into treatment options that exist.
I've had CFS/ME for a decade, so I'm not expecting a cure, but anything that can sustainably get me a few percentile points is a good thing. Plus, what a puzzle!
I've had CFS/ME for a decade, so I'm not expecting a cure, but anything that can sustainably get me a few percentile points is a good thing. Plus, what a puzzle!
Pretty much any specialist you talk to about ME/CFS&LC is going to view it through the lens of their specialty. We don't have a gestalt view ("neuroimmune" is the best we've got), and I'm not ambitious enough to try and take that on. You see microfuckery in many major systems.
July 14, 2025 at 2:51 PM
Pretty much any specialist you talk to about ME/CFS&LC is going to view it through the lens of their specialty. We don't have a gestalt view ("neuroimmune" is the best we've got), and I'm not ambitious enough to try and take that on. You see microfuckery in many major systems.
I believe the Day will be
When the Jay will giggle
At his new white House the Earth
That, too, halt a little –
When the Jay will giggle
At his new white House the Earth
That, too, halt a little –
January 19, 2025 at 9:01 PM
I believe the Day will be
When the Jay will giggle
At his new white House the Earth
That, too, halt a little –
When the Jay will giggle
At his new white House the Earth
That, too, halt a little –
I suppose the time will come
Aid it in the coming
When the Bird will crowd the Tree
And the Bee be booming –
I suppose the time will come
Hinder it a little
When the Corn in Silk will dress
And in Chintc the Apple
Aid it in the coming
When the Bird will crowd the Tree
And the Bee be booming –
I suppose the time will come
Hinder it a little
When the Corn in Silk will dress
And in Chintc the Apple
January 19, 2025 at 9:01 PM
I suppose the time will come
Aid it in the coming
When the Bird will crowd the Tree
And the Bee be booming –
I suppose the time will come
Hinder it a little
When the Corn in Silk will dress
And in Chintc the Apple
Aid it in the coming
When the Bird will crowd the Tree
And the Bee be booming –
I suppose the time will come
Hinder it a little
When the Corn in Silk will dress
And in Chintc the Apple
per this book her handwriting is known to have changed over time, maybe because of her eye problems & the handwriting shifts are how a lot of her work is dated. however, I'm under the distinct impression none of her poetry was easy to decipher
January 19, 2025 at 8:57 PM
per this book her handwriting is known to have changed over time, maybe because of her eye problems & the handwriting shifts are how a lot of her work is dated. however, I'm under the distinct impression none of her poetry was easy to decipher