Siyuan (Steven) Wang
@sstevenwang.bsky.social
Image-based spatial multi-omics. Associate Professor at Yale. NIH Director's New Innovator Awardee. MIT Technology Review 35 Innovators Under 35.
Glad to share our latest publication in Nature Genetics: Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. In this work, we generated the first single-cell 3D genome atlases of any cancer using any technique. 1/12
August 19, 2025 at 4:53 PM
Glad to share our latest publication in Nature Genetics: Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. In this work, we generated the first single-cell 3D genome atlases of any cancer using any technique. 1/12
In eukaryotes, epigenetic states and 3D chromatin folding are critical regulators of many genomic functions. While these mechanisms are known to be closely interlinked, studying their relationship remains challenging due to technical limitations. 2/8
June 26, 2025 at 4:29 AM
In eukaryotes, epigenetic states and 3D chromatin folding are critical regulators of many genomic functions. While these mechanisms are known to be closely interlinked, studying their relationship remains challenging due to technical limitations. 2/8
Introducing Epi-PHR, the first non-disruptive, high-genomic-resolution, image-based epigenetic profiling method. Allelic Epi-PHR generates the first single-cell phased examination of histone mark deposition and 3D genome architecture at an imprinted locus by any technique. 1/8
June 26, 2025 at 4:29 AM
Introducing Epi-PHR, the first non-disruptive, high-genomic-resolution, image-based epigenetic profiling method. Allelic Epi-PHR generates the first single-cell phased examination of histone mark deposition and 3D genome architecture at an imprinted locus by any technique. 1/8