Srimeenakshi S
@srimeenakshi.bsky.social
RNA biologist 🧬 | Postdoc @zarnack-group in JMU Würzburg | From wet lab roots to computational biology
Reposted by Srimeenakshi S
Our new Cluster for Nucleic Acid Sciences and Technologies has kicked off in Eichstätt. NUCLEATE unites experts from Würzburg and Munich to advance nucleic acid science and develop future medical applications.
#NUCLEATE #RNA #DNA #Biomedicine
@uni-wuerzburg.de @lmumuenchen.bsky.social @tum.de
#NUCLEATE #RNA #DNA #Biomedicine
@uni-wuerzburg.de @lmumuenchen.bsky.social @tum.de
November 14, 2025 at 8:00 PM
Our new Cluster for Nucleic Acid Sciences and Technologies has kicked off in Eichstätt. NUCLEATE unites experts from Würzburg and Munich to advance nucleic acid science and develop future medical applications.
#NUCLEATE #RNA #DNA #Biomedicine
@uni-wuerzburg.de @lmumuenchen.bsky.social @tum.de
#NUCLEATE #RNA #DNA #Biomedicine
@uni-wuerzburg.de @lmumuenchen.bsky.social @tum.de
Reposted by Srimeenakshi S
Great time visiting the groups of Carmo Fonseca, Joel Perez-Perri, and Nuno Morais (@nmoraislab.bsky.social) at Gulbenkian Institute for Molecular Medicine (GIMM) in Lisbon 🇵🇹
Thanks for great discussions on nuclear speckles, RNA-binding proteins, and other exciting topics!
#ScienceVisit #RNA #GIMM
Thanks for great discussions on nuclear speckles, RNA-binding proteins, and other exciting topics!
#ScienceVisit #RNA #GIMM
October 21, 2025 at 8:09 PM
Great time visiting the groups of Carmo Fonseca, Joel Perez-Perri, and Nuno Morais (@nmoraislab.bsky.social) at Gulbenkian Institute for Molecular Medicine (GIMM) in Lisbon 🇵🇹
Thanks for great discussions on nuclear speckles, RNA-binding proteins, and other exciting topics!
#ScienceVisit #RNA #GIMM
Thanks for great discussions on nuclear speckles, RNA-binding proteins, and other exciting topics!
#ScienceVisit #RNA #GIMM
Reposted by Srimeenakshi S
We’re kicking off the bioinformatics part of the #emboiclip2 course today! Excited to dive into the data side of iCLIP. 💻🧬
September 11, 2025 at 10:02 AM
We’re kicking off the bioinformatics part of the #emboiclip2 course today! Excited to dive into the data side of iCLIP. 💻🧬
hurray!! @zarnack-group.bsky.social is in bluesky!! 🎉
Welcome to bluesky @zarnack-group.bsky.social !!!
#bioinformatics #RNA #splicing #RNAmodification #m6A
#bioinformatics #RNA #splicing #RNAmodification #m6A
July 8, 2025 at 2:44 PM
hurray!! @zarnack-group.bsky.social is in bluesky!! 🎉
Reposted by Srimeenakshi S
How to find binding sites or your favorite #RNA binding protein?
Join us for the EMBO practical course "iCLIP2, mapping protein RNA interactions: from A to Z". from 7.-12. September in Genoa, Italy
Learn more and register here:
meetings.embo.org/event/25-icl...
@embo.org @mixmue.bsky.social
Join us for the EMBO practical course "iCLIP2, mapping protein RNA interactions: from A to Z". from 7.-12. September in Genoa, Italy
Learn more and register here:
meetings.embo.org/event/25-icl...
@embo.org @mixmue.bsky.social
iCLIP2, mapping protein-RNA interactions: from A to Z
RNA is increasingly recognized as a key therapeutic target , driving the development of RNA-based therapeutics for a broad spectrum of diseases. RNA-binding proteins (RBPs) play a fundamental ro…
meetings.embo.org
March 26, 2025 at 7:58 AM
How to find binding sites or your favorite #RNA binding protein?
Join us for the EMBO practical course "iCLIP2, mapping protein RNA interactions: from A to Z". from 7.-12. September in Genoa, Italy
Learn more and register here:
meetings.embo.org/event/25-icl...
@embo.org @mixmue.bsky.social
Join us for the EMBO practical course "iCLIP2, mapping protein RNA interactions: from A to Z". from 7.-12. September in Genoa, Italy
Learn more and register here:
meetings.embo.org/event/25-icl...
@embo.org @mixmue.bsky.social
Reposted by Srimeenakshi S
We are very happy to invite you to our 8th edition of the Rhineland RNA Club @mpiage.bsky.social with great local speakers and Julian König @koenig-lab.bsky.social as our invited speaker. All #RNA enthusiasts are welcome. Organized by @katleppek.bsky.social and @inahuppertz.bsky.social. #RNAsky
March 7, 2025 at 9:29 AM
We are very happy to invite you to our 8th edition of the Rhineland RNA Club @mpiage.bsky.social with great local speakers and Julian König @koenig-lab.bsky.social as our invited speaker. All #RNA enthusiasts are welcome. Organized by @katleppek.bsky.social and @inahuppertz.bsky.social. #RNAsky
Reposted by Srimeenakshi S
Robert-Koch-Postdoktorandenpreis für den Themenbereich Immunologie (€ 5.000) / Bewerbungsschluss: 14. März 2025
Die DGfI hat ein Vorschlagsrecht für den Robert-Koch-Postdoktorandenpreis im Bereich Immunologie.
Mehr Informationen unter: dgfi.org/preise/koch-...
Die DGfI hat ein Vorschlagsrecht für den Robert-Koch-Postdoktorandenpreis im Bereich Immunologie.
Mehr Informationen unter: dgfi.org/preise/koch-...
February 28, 2025 at 3:00 PM
Robert-Koch-Postdoktorandenpreis für den Themenbereich Immunologie (€ 5.000) / Bewerbungsschluss: 14. März 2025
Die DGfI hat ein Vorschlagsrecht für den Robert-Koch-Postdoktorandenpreis im Bereich Immunologie.
Mehr Informationen unter: dgfi.org/preise/koch-...
Die DGfI hat ein Vorschlagsrecht für den Robert-Koch-Postdoktorandenpreis im Bereich Immunologie.
Mehr Informationen unter: dgfi.org/preise/koch-...
Reposted by Srimeenakshi S
PhD position vacant in the lab. Please spread the news. Study topic: Mammalian nuclear RNA production and turnover systems. Learn more about the lab here: www.mRNP.au.dk
February 20, 2025 at 9:53 AM
PhD position vacant in the lab. Please spread the news. Study topic: Mammalian nuclear RNA production and turnover systems. Learn more about the lab here: www.mRNP.au.dk
Reposted by Srimeenakshi S
New postdoc opportunity in the THJ lab! Please share to anyone interested in nuclear RNA biology
@molbiolau.bsky.social
mbg.au.dk/en/news-and-...
@molbiolau.bsky.social
mbg.au.dk/en/news-and-...
Postdoc positions in Nuclear RNA Biology - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University
mbg.au.dk
February 7, 2025 at 12:41 PM
New postdoc opportunity in the THJ lab! Please share to anyone interested in nuclear RNA biology
@molbiolau.bsky.social
mbg.au.dk/en/news-and-...
@molbiolau.bsky.social
mbg.au.dk/en/news-and-...
Reposted by Srimeenakshi S
Hello Everyone! 👋 Nucleic Acids Research is excited to be on Bluesky! Please follow us for the latest #Research, #Breakthrough articles, journal issues and more. Also, please consider adding us to your starter packs!
January 31, 2025 at 12:33 PM
Hello Everyone! 👋 Nucleic Acids Research is excited to be on Bluesky! Please follow us for the latest #Research, #Breakthrough articles, journal issues and more. Also, please consider adding us to your starter packs!
Reposted by Srimeenakshi S
"m6A ‘encodes’ a dedicated mRNA decay pathway". Thank you Eytan for highlighting our work in @natrevmcb.bsky.social
Read the story here:
www.nature.com/articles/s41...
#RNA #m6A #translation
PS: Still thinking what the banana means.
Read the story here:
www.nature.com/articles/s41...
#RNA #m6A #translation
PS: Still thinking what the banana means.
January 22, 2025 at 1:20 PM
"m6A ‘encodes’ a dedicated mRNA decay pathway". Thank you Eytan for highlighting our work in @natrevmcb.bsky.social
Read the story here:
www.nature.com/articles/s41...
#RNA #m6A #translation
PS: Still thinking what the banana means.
Read the story here:
www.nature.com/articles/s41...
#RNA #m6A #translation
PS: Still thinking what the banana means.
Reposted by Srimeenakshi S
It is finally out! My first Science paper is online and it does not seem real😃. I am Incredibly happy! Really thanks to all my coauthors and special mention to my incredible supervisor Ivan Dikic for all the support and trust ! 🫶. #RNA #Proteostasis #ubiquitin #autophagy #RP
doi.org/10.1126/scie...
doi.org/10.1126/scie...
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
RNA splicing enables the functional adaptation of cells to changing contexts. Impaired splicing has been associated with diseases, including retinitis pigmentosa, but the underlying molecular mechanis...
doi.org
November 15, 2024 at 7:14 PM
It is finally out! My first Science paper is online and it does not seem real😃. I am Incredibly happy! Really thanks to all my coauthors and special mention to my incredible supervisor Ivan Dikic for all the support and trust ! 🫶. #RNA #Proteostasis #ubiquitin #autophagy #RP
doi.org/10.1126/scie...
doi.org/10.1126/scie...
Reposted by Srimeenakshi S
I’m thrilled to share a collaborative story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu. We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes
The CCR4-NOT complex is a major regulator of eukaryotic messenger RNA (mRNA) stability. Slow decoding during translation promotes association of CCR4-NOT with ribosomes, accelerating mRNA degradation....
www.science.org
November 22, 2024 at 6:09 PM
I’m thrilled to share a collaborative story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu. We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Srimeenakshi S
Reposted by Srimeenakshi S
I’m excited to share this story. We found that mutating an RNA binding protein’s ability to bind RNA did not remove all biological function, but when combined with a mutation that affects protein interactions, the RBP no longer functioned.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA
Like all canonical PUF proteins, C. elegans FBF-2 binds to specific RNAs via tripartite recognition motifs (TRMs). Here we report that an FBF-2 mutant protein that cannot bind to RNA, is nonetheless b...
www.biorxiv.org
October 26, 2024 at 11:42 AM
I’m excited to share this story. We found that mutating an RNA binding protein’s ability to bind RNA did not remove all biological function, but when combined with a mutation that affects protein interactions, the RBP no longer functioned.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...