Covalent adaptable networks (CANs) are sustainable polymeric materials that combine mechanical robustness with reprocessability through dynamic covalent bonds. Their mechanical behavior is governed by...

To unlock the potential of molecular engineering for practical quantum sensing and computing, it is essential to create and control pure magnetic states in molecular systems. Singlet fission (SF) in o...

Multiexciton (ME) mechanisms hold great promise for enhancing energy conversion efficiency in optoelectronic and photochemical systems. In singlet fission (SF), the generation of two triplet excitons ...

Fluorescence imaging is crucial for studying biology. Triplet state quenchers (TSQs), especially cyclooctatetraene (COT), can dramatically improve fluorophore performance, particularly when linked int...

The Blatter radical has been suggested as a building block in future molecular spintronic devices because of its radical character and expected long s…

The last few years have seen the development of numerous deep learning-based protein–ligand docking methods. They offer huge promise in terms of speed and accuracy. However, despite claims of…

Nature Reviews Chemistry, Published online: 31 January 2025; doi:10.1038/s41570-025-00686-7Ever-increasing society needs have made thermosets crucial, but their recycling poses considerable challenges. Dynamic covalent chemistry (DCC) offers a solution,…

Chemical Science are delighted to launch a new Lectureship in our 15th anniversary year in 2025 to recognise and celebrate the significant contributions our authors make to the chemical sciences commu...

We have developed a set of multicolor 3D-printed structural and molecular orbital models for use in a first-semester organic chemistry course. These models provide visual and tactile insights regarding aspects of organic structure, reactivity, and mechanistic “arrow pushing”. The set includes: 1. orbital models of σ and π bonding in methane and ethylene, 2. σCH–σ*CH hyperconjugation in staggered and eclipsed ethane conformations, 3. LUMO accessibility in SN2 electrophiles and HOMO–LUMO orbital interactions in SN2 transition states, 4. E2 transition state structure and orbital interactions in β-hydrogen removal and π bond formation, 5. σCH–pC hyperconjugation in the ethyl cation, 6. transition state structure and σCH–pC orbital interactions in a carbocation 1,2-hydride shift, 7. late and early, respectively, Br• and Cl• H atom radical abstraction transition state structures and SOMO orbitals, 8. bromonium ion structure and LUMO orbital, 9. protonated epoxide ion and neutral epoxide structures and LUMO orbitals, 10. transition state structure and orbital interactions in a hydroboration reaction, 11. transition state structure and orbital interactions in the lithium aluminum hydride reduction of formaldehyde, and 12. π molecular orbitals in 1,3-butadiene. The prints are made with hobby-grade 5-color 3D fused deposition modeling (FDM) printers and sized to provide compact take-home class handouts for each student or projected in-class with a document camera. Models are fabricated with orbital or electron density surface bisections and text annotations to enhance information content. Student perceptions of this set of 3D-printed molecular models are generally favorable and have improved their understanding of course materials.

Degradable thermoset multimaterials can be synthesized from a commercially accessible, biosourced monomer using orthogonal polymerizations in a single pot; after selective degredation, the resulting s...