Sim Sakong
simsakong.bsky.social
Sim Sakong
@simsakong.bsky.social
Biophysicist in🇨🇭/ bridging postDoc in LCBM, EPFL
Ph.D. in Suter’s lab and Fierz’s lab, EPFL

#targetsearch #transcription #singlemoleculeimaging
Many thanks to my PhD supervisors, @beatfierz.bsky.social and @davidsuter.bsky.social, for their invaluable guidance and support throughout my journey!
March 12, 2025 at 6:49 PM
Reposted by Sim Sakong
Check out our #openaccess article "A Site-Specific Click Chemistry Approach to Di-Ubiquitylate H1 Variants Reveals Position-Dependent Stimulation of the DNA Repair Protein RNF168"
▶️ tinyurl.com/27uxumme
@beatfierz.bsky.social
A Site‐Specific Click Chemistry Approach to Di‐Ubiquitylate H1 Variants Reveals Position‐Dependent Stimulation of the DNA Repair Protein RNF168
We developed a click chemistry approach to di-ubiquitylate histone H1 at relevant DNA repair-associated positions (H1KxUb2) to probe its effect on the E3 ligase RNF168. We demonstrate that H1KxUb2 st...
onlinelibrary.wiley.com
December 19, 2024 at 12:29 PM