Rasmus Siersbaek
@siersbaek.bsky.social
Molecular cancer biologist fascinated by gene regulation, chromatin and epigenetics. Based in Denmark.
Reposted by Rasmus Siersbaek
Nucleosome fibre topology guides transcription factor binding to enhancers www.nature.com/articles/s41...
▶️motif recognition on mononucleosomes affects only an individual TF binding
▶️When bound together, TFs act cooperatively or competitively to target nucleosome arrays with defined 3D organization
▶️motif recognition on mononucleosomes affects only an individual TF binding
▶️When bound together, TFs act cooperatively or competitively to target nucleosome arrays with defined 3D organization
December 18, 2024 at 6:53 PM
Nucleosome fibre topology guides transcription factor binding to enhancers www.nature.com/articles/s41...
▶️motif recognition on mononucleosomes affects only an individual TF binding
▶️When bound together, TFs act cooperatively or competitively to target nucleosome arrays with defined 3D organization
▶️motif recognition on mononucleosomes affects only an individual TF binding
▶️When bound together, TFs act cooperatively or competitively to target nucleosome arrays with defined 3D organization
Extremely grateful to @carlsbergfondet.dk for supporting our research on #MYC in #cancer with a Semper Ardens Accelerate grant🙌🏻😄 I cannot wait to get started!! 😄😄
December 17, 2024 at 7:00 PM
Extremely grateful to @carlsbergfondet.dk for supporting our research on #MYC in #cancer with a Semper Ardens Accelerate grant🙌🏻😄 I cannot wait to get started!! 😄😄
📢 Looking for a #postdoc position in the intersection of #cancer, #chromatin and #epigenetics??? Still a few days left to apply to our lab in wonderful Denmark as part of the new translational cancer hub initiative🇩🇰🧪👇🏻
Postdoc Positions in Translational Cancer Research
Application deadline: 30 November 2024 at 23.59 hours local Danish time.
fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com
November 28, 2024 at 6:20 PM
📢 Looking for a #postdoc position in the intersection of #cancer, #chromatin and #epigenetics??? Still a few days left to apply to our lab in wonderful Denmark as part of the new translational cancer hub initiative🇩🇰🧪👇🏻
First post @bsky.app 😄😄 wanted to highlight this very innovative tech to investigate #chromatin binding! Congrats to @mitchguttman.bsky.social and the whole team👏🏻👏🏻
www.nature.com/articles/s41...
www.nature.com/articles/s41...
ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics
ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...
www.nature.com
November 27, 2024 at 6:56 PM
First post @bsky.app 😄😄 wanted to highlight this very innovative tech to investigate #chromatin binding! Congrats to @mitchguttman.bsky.social and the whole team👏🏻👏🏻
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Rasmus Siersbaek
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
November 24, 2024 at 1:54 PM
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...