Secombe
secombe-lab.bsky.social
Secombe
@secombe-lab.bsky.social
We love all things related to KDM5, chromatin and transcription. Interested in understanding the basis of KDM5-induced neurodevelopmental disorders using Drosophila and human iPSC models. 🇦🇺🇺🇸🏳️‍🌈 | secombelab.org |
Reposted by Secombe
Frikkin amazing stuff.
November 26, 2025 at 8:29 AM
Reposted by Secombe
Three Einstein graduate students were honored recently for their contributions to #scientific #research at the 29th Julius Marmur Award symposium. Einstein's Graduate Programs in the Biomedical Sciences established the prize in memory of Dr. Marmur, a pioneering molecular biologist and mentor.
Graduate Student Researchers Honored at 2025 Marmur Symposium
bit.ly
April 21, 2025 at 8:37 PM
Reposted by Secombe
The US National Institutes of Health has terminated nearly 800 research projects at a breakneck pace, wiping out significant chunks of funding to entire scientific fields

Read the full story: https://go.nature.com/3EuFRPV
April 18, 2025 at 10:19 AM
Reposted by Secombe
Donald Trump and Elon Musk are disrupting a breakthrough cancer treatment so they can fund tax cuts for billionaires.

Tell your friends.
NIH scientists have a cancer breakthrough. Layoffs are delaying it.
A big step forward in cancer therapy has been slowed by layoffs and new restrictions at the National Institutes of Health, where it was developed.
www.washingtonpost.com
April 6, 2025 at 11:28 PM
Reposted by Secombe
Last few days to apply!
Post-doctoral position 3 years Wellcome funded in UK
To investigate how experience shapes the brain
Drosophila neurogenetics, imaging, behaviour
Deadline 19/3/25
Pls RP.
#drosophila
#postdoc
#jobs
Apply here

edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
Research Fellow in Neurogenetics to investigate how experience shapes the brain - School of Biosciences - 98709 - Grade 7
A Research Fellow with experience in behavioural neurogenetics of Drosophila is sought. The aim of the project is to investigate how experience and behaviour shape the brain throughout life, the impac...
edzz.fa.em3.oraclecloud.com
March 15, 2025 at 8:58 AM
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Reposted by Secombe
"When you hear about patients surviving stage 4 cancer because of immunotherapy, that was based on NIH research over many decades. When you hear about sickle cell disease being cured because of CRISPR gene editing, that was built on years of research supported by NIH"

apnews.com/article/nih-...
Renowned geneticist Francis Collins retires from NIH, urging 'respect' for embattled workers
Dr. Francis Collins, a renowned geneticist, and former longtime director of the National Institutes of Health, is retiring from the government agency and urging “respect” for its embattled workers.
apnews.com
March 1, 2025 at 9:44 PM
Reposted by Secombe
Despite court order, NIH grants remain frozen. Newly awarded grants, grants with fundable scores, & funds for a new budget cycle of a current project are all *FROZEN*🥶 and not being released. US research is being choked to death & is on life support right now www.motherjones.com/politics/202...
NIH is again throttling research funding in defiance of a federal court order
A freeze on "new and continuation awards" will "remain in place" pending DEI review, states a new internal memo.
www.motherjones.com
February 26, 2025 at 12:04 PM
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Join the Department of Developmental & Molecular Biology @einsteinmededu.bsky.social ! 🧬✨
Are you passionate about cutting-edge research and collaborative science? We are looking for you😉
Come be part of a department where curiosity meets impact! 🚀
Learn more and join us👇
#ResearchExcellence #JoinUs
Faculty-Tenure Track, Department of Developmental and Molecular Biology - Bronx, New York job with Albert Einstein College of Medicine | 12835514
Faculty-Tenure Track, Department of Developmental and Molecular Biology US-NY-Bronx Job ID: 2025-17126 Type: Research # of Openings: 1 Category: F...
www.nature.com
February 26, 2025 at 3:31 AM
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The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
NIH funding freeze stalls applications on $1.5 billion in medical research funds
The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.
www.npr.org
February 22, 2025 at 6:39 PM
Reposted by Secombe
Here are some data documenting the funding "pause" pulled from NIH Reporter. Current results (FY25) (Red) are compared with results from FY21 (first year of Biden Administration) and FY24.

Note that data from Reporter lag behind release of NoAs by ~1 week.

I will be tracking this going forward.
February 21, 2025 at 4:49 AM
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I wrote up an FAQ about the recent federal grant cuts. A few points: 🧵
A FAQ on federal research cuts
...
open.substack.com
February 20, 2025 at 3:35 AM
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The Trump administration’s actions will be tested in the courts and fought by unions. But scientists and university leaders said they have another fight ahead: They need to convince Americans — and Congress — that science is worth the investment.
Science under siege: Trump cuts threaten to undermine decades of research
Sweeping layoffs, funding freezes and executive orders have provoked outcry among federal researchers and their university partners, who fear that science itself is under siege.
nbcnews.to
February 19, 2025 at 8:50 PM
Reposted by Secombe
Looking for an enthusiastic post-doc to investigate how experience shapes the brain. Drosophila neurogenetics, molecular and cellular mechanisms, imaging, optogenetics, neural circuits and behaviour will be used. At University of Birmingham campus, UK. Application deadline 19 March.
Pls RT.
February 10, 2025 at 8:58 AM
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University leaders right now…🚽🤢
February 7, 2025 at 11:28 PM
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AAMC - Congress must support robust federal funding for NIH
Congress must support robust federal funding for the NIH
NIH-funded research supports scientific discovery that benefits millions of Americans.
www.aamc.org
February 7, 2025 at 1:17 AM
Reposted by Secombe
Excellent perspective by @lisamjarvis.bsky.social @bloomberg.com on the deep freeze at NIH
Trump's NIH Freeze Puts Scientific Research at Risk
America’s best scientific minds are scrambling to determine the impact of the disruption.
www.bloomberg.com
January 24, 2025 at 9:28 PM
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I hear there are stories coming, but putting the brakes on our country’s world-leading medical research system feels like a five alarm fire and I don’t see a newspaper that even has it on the front page yet
Shutting down medical research — not just within NIH, but everywhere that’s funded by NIH — will have long-term effects on medicine & short-term effects on state, higher education & hospital budgets. This affects all of us, not just researchers.
The assault on NIH is a test for how the national media covers the Trump admin: Trump is shutting down medical research!

That is easy to communicate. Will they treat it as a 5 alarm fire in a way that forces the government to respond, or will they downplay & caveat it?
January 23, 2025 at 3:29 AM
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The antidote for despair is action ❤️

* Dial (202) 224-3121
* Enter zip code
* Leave voicemail
* Say “My name is ___, I’m a constituent in [town]. (If clinician/scientist, say so)

“The NIH freeze harms research and patients and must be lifted immediately.”

Be brief. Staffers tally all calls. Go! ✅
NIH funding supports the vast majority of all biomedical research in the United States. Virtually every advance in American medicine and biological science comes from NIH. This is a blow against American science.

Call Congress, 202-224-3121.
All NIH study sections canceled indefinitely. This will halt science and devastate research budgets in universities.
January 23, 2025 at 3:21 AM
I have officially reached that dreaded phase of grant writing where my files are called _final. And then _finalV2, _final_final etc. 😂
January 13, 2025 at 12:47 PM
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We're thankful for the Einstein alumni who made history in 1999 when they opened the doors to the first student-run health clinic in New York City, called the ECHO Free Clinic. For its 25th anniversary, several alumni who helped shape that clinic in its earliest days reflect on its legacy. #MedSky
ECHO Anniversary: In the Room Where it Happened | Einstein Magazine
As the Albert Einstein College of Medicine’s ECHO marks 25 years, Einstein alumni recall the earliest day of the free clinic, which became a national model.
bit.ly
November 27, 2024 at 5:04 PM
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Research funded by NIH generated $2.46 in economic activity for every $1 of funding in 2023 [a total of $92.9 billion]

www.fiercebiotech.com/research/rep...
Report: Every dollar of NIH research funding doubles in economic returns
Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an
www.fiercebiotech.com
November 17, 2024 at 11:56 PM