Martin Holub, Ph.D.
@scimartin.bsky.social
www.martinholub.com | www.unomr.com
PhD Bioengineering | science + technology | talks biotech, biosecurity, synbio
PhD Bioengineering | science + technology | talks biotech, biosecurity, synbio
If the people who stole 90'000 EUR worth of escargots had this in mind, shall they be forgiven
December 1, 2025 at 1:20 PM
If the people who stole 90'000 EUR worth of escargots had this in mind, shall they be forgiven
Reposted by Martin Holub, Ph.D.
#JPM2026 Nucleate is hosting our annual reception at SF’s Exploratorium on Jan 14 — and poster applications are now OPEN!
Interested in sponsoring? Email Oliver Dodd, oliver@nucleate.org
Register here: https://loom.ly/Qi88zgo
Apply to present: https://loom.ly/NZ58s3w
Interested in sponsoring? Email Oliver Dodd, oliver@nucleate.org
Register here: https://loom.ly/Qi88zgo
Apply to present: https://loom.ly/NZ58s3w
Nucleate JPM'26 Reception · Luma
🌟 Get ready for an unforgettable evening at San Francisco’s iconic Exploratorium! 🌟
🎉 We’re thrilled to invite you back to Nucleate’s JPM ’26 Reception,…
luma.com
November 19, 2025 at 3:06 PM
#JPM2026 Nucleate is hosting our annual reception at SF’s Exploratorium on Jan 14 — and poster applications are now OPEN!
Interested in sponsoring? Email Oliver Dodd, oliver@nucleate.org
Register here: https://loom.ly/Qi88zgo
Apply to present: https://loom.ly/NZ58s3w
Interested in sponsoring? Email Oliver Dodd, oliver@nucleate.org
Register here: https://loom.ly/Qi88zgo
Apply to present: https://loom.ly/NZ58s3w
Reposted by Martin Holub, Ph.D.
Event Alert: AI in Drug Development – Beyond the Usual Playbook
📅 Nov 12 | 5–8 PM ET
📍 Sanofi, Cambridge MA
🔗 Apply to attend or pitch → https://luma.com/2tvhzypm
📅 Nov 12 | 5–8 PM ET
📍 Sanofi, Cambridge MA
🔗 Apply to attend or pitch → https://luma.com/2tvhzypm
November 20, 2025 at 3:04 PM
Event Alert: AI in Drug Development – Beyond the Usual Playbook
📅 Nov 12 | 5–8 PM ET
📍 Sanofi, Cambridge MA
🔗 Apply to attend or pitch → https://luma.com/2tvhzypm
📅 Nov 12 | 5–8 PM ET
📍 Sanofi, Cambridge MA
🔗 Apply to attend or pitch → https://luma.com/2tvhzypm
Reposted by Martin Holub, Ph.D.
Do you want to engineer mammalian protein secretion? We present STAMPS: signal-peptide transformer for tuning mammalian protein secretion! Led by Jacopo in the lab, in collaboration with Cleo Kontoravdi and colleagues at Astra Zeneca, STAMPS is now on Bioarxiv!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
STAMPS: Signal-peptide Transformer for Augmenting Mammalian Protein Secretion
While secretion plays a key role in the diverse applications of cell engineering, to date only a handful of mammalian signal peptides have been characterised in depth and systematic efforts to build n...
www.biorxiv.org
November 21, 2025 at 9:10 AM
Do you want to engineer mammalian protein secretion? We present STAMPS: signal-peptide transformer for tuning mammalian protein secretion! Led by Jacopo in the lab, in collaboration with Cleo Kontoravdi and colleagues at Astra Zeneca, STAMPS is now on Bioarxiv!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Martin Holub, Ph.D.
Chemical biology 2026 www.embl.org/about/info/c...
Chemical biology 2026
www.embl.org
November 20, 2025 at 12:29 PM
Chemical biology 2026 www.embl.org/about/info/c...
November 21, 2025 at 1:53 PM
Reposted by Martin Holub, Ph.D.
Pakistan has launched its first nationwide HPV vaccination campaign, a historic step to protect nearly 13 million girls from cervical cancer.
At the heart of the campaign are doctors like Dr Saima Zubair, whose advocacy in twelve languages has helped build trust where it matters most. 🧵
At the heart of the campaign are doctors like Dr Saima Zubair, whose advocacy in twelve languages has helped build trust where it matters most. 🧵
November 20, 2025 at 6:57 PM
Pakistan has launched its first nationwide HPV vaccination campaign, a historic step to protect nearly 13 million girls from cervical cancer.
At the heart of the campaign are doctors like Dr Saima Zubair, whose advocacy in twelve languages has helped build trust where it matters most. 🧵
At the heart of the campaign are doctors like Dr Saima Zubair, whose advocacy in twelve languages has helped build trust where it matters most. 🧵
Reposted by Martin Holub, Ph.D.
If you use GMail, AI (Gemini) was turned on yesterday by default and now scans all of your content for machine learning. To turn off, go to Settings>General and scroll down. Uncheck the box for "Smart features."
There's other "Smart" add-ons as well, but that's the one that reads your content.
There's other "Smart" add-ons as well, but that's the one that reads your content.
November 20, 2025 at 5:32 PM
If you use GMail, AI (Gemini) was turned on yesterday by default and now scans all of your content for machine learning. To turn off, go to Settings>General and scroll down. Uncheck the box for "Smart features."
There's other "Smart" add-ons as well, but that's the one that reads your content.
There's other "Smart" add-ons as well, but that's the one that reads your content.
November 19, 2025 at 10:22 AM
Reposted by Martin Holub, Ph.D.
Rift Valley fever is a viral disease affecting animals and humans.
Spread by mosquitoes or infected animal contact, it threatens public health and economies across Africa.
Moving from reaction to anticipatory action is key to protecting lives and livelihoods.
bit.ly/4hU2PPF
#RVF #RiftValleyFever
Spread by mosquitoes or infected animal contact, it threatens public health and economies across Africa.
Moving from reaction to anticipatory action is key to protecting lives and livelihoods.
bit.ly/4hU2PPF
#RVF #RiftValleyFever
November 18, 2025 at 2:21 PM
Rift Valley fever is a viral disease affecting animals and humans.
Spread by mosquitoes or infected animal contact, it threatens public health and economies across Africa.
Moving from reaction to anticipatory action is key to protecting lives and livelihoods.
bit.ly/4hU2PPF
#RVF #RiftValleyFever
Spread by mosquitoes or infected animal contact, it threatens public health and economies across Africa.
Moving from reaction to anticipatory action is key to protecting lives and livelihoods.
bit.ly/4hU2PPF
#RVF #RiftValleyFever
The overwhelming majority of independent research finds that cigarette filters do not reduce the health risks of smoking.
Cigarette filters are the second-largest plastic pollutant on Earth, and do not reduce health harms.
Ban filters and protect the planet.
Learn more 👉 bit.ly/3LJgb5v #TobaccoExposed
Ban filters and protect the planet.
Learn more 👉 bit.ly/3LJgb5v #TobaccoExposed
November 19, 2025 at 10:20 AM
The overwhelming majority of independent research finds that cigarette filters do not reduce the health risks of smoking.
Reposted by Martin Holub, Ph.D.
Hanoi is targeting its first university spinout by the end of 2025, following the government's issuing of a legal framework that enables institutions to incorporate businesses and invest in them thenextleap.is/news/vietnam...
The Next Leap » Hanoi targets first university spinout by year's end
Hanoi aims to produce its first university spinout by year-end after the central government issued clear enabling regulations.
thenextleap.is
November 4, 2025 at 11:12 AM
Hanoi is targeting its first university spinout by the end of 2025, following the government's issuing of a legal framework that enables institutions to incorporate businesses and invest in them thenextleap.is/news/vietnam...
Reposted by Martin Holub, Ph.D.
Nucleate France + PATH are hosting Inside AI: Choosing the Right Path to Value Creation at TechBio France 2025 - a deep dive into how AI can drive real impact in life sciences.
📅 Dec 4, 2025
📍 Future4care, Paris
Register here: https://www.eventbrite.fr/e/techbio-france-2025-tickets-1850540308879
📅 Dec 4, 2025
📍 Future4care, Paris
Register here: https://www.eventbrite.fr/e/techbio-france-2025-tickets-1850540308879
November 18, 2025 at 3:04 PM
Nucleate France + PATH are hosting Inside AI: Choosing the Right Path to Value Creation at TechBio France 2025 - a deep dive into how AI can drive real impact in life sciences.
📅 Dec 4, 2025
📍 Future4care, Paris
Register here: https://www.eventbrite.fr/e/techbio-france-2025-tickets-1850540308879
📅 Dec 4, 2025
📍 Future4care, Paris
Register here: https://www.eventbrite.fr/e/techbio-france-2025-tickets-1850540308879
Reposted by Martin Holub, Ph.D.
📢 Register now for our second session of the Women Leading Life Sciences Virtual Series!
https://luma.com/xreq45fm
We’re excited to continue 2025-2026 virtual series in December 2025, featuring Gabriele Niederauer, Co-Founder and Chief Executive Officer at Freyya, Inc.
https://luma.com/xreq45fm
We’re excited to continue 2025-2026 virtual series in December 2025, featuring Gabriele Niederauer, Co-Founder and Chief Executive Officer at Freyya, Inc.
Women Leading Life Sciences Virtual Series with Gabriele Niederauer · Zoom · Luma
About this Virtual Series
As part of Nucleate PATH, this program is designed to inspire and empower the next generation of life science leaders by spotlighting…
luma.com
November 18, 2025 at 7:02 PM
📢 Register now for our second session of the Women Leading Life Sciences Virtual Series!
https://luma.com/xreq45fm
We’re excited to continue 2025-2026 virtual series in December 2025, featuring Gabriele Niederauer, Co-Founder and Chief Executive Officer at Freyya, Inc.
https://luma.com/xreq45fm
We’re excited to continue 2025-2026 virtual series in December 2025, featuring Gabriele Niederauer, Co-Founder and Chief Executive Officer at Freyya, Inc.
doing science in the US == navigating a mine field
www.science.org/content/arti...
www.science.org/content/arti...
U.S. Congress considers sweeping ban on Chinese collaborations
Researchers speak out against proposal that would bar funding for U.S. scientists working with Chinese partners or training Chinese students
www.science.org
November 19, 2025 at 10:07 AM
doing science in the US == navigating a mine field
www.science.org/content/arti...
www.science.org/content/arti...
Reposted by Martin Holub, Ph.D.
Was interesting to hear today about the annual “SynBio Challenges” competition that has got going in China as a cheaper/free alternative to iGEM - m.synbiochallenges.com/application/...
November 11, 2025 at 3:43 PM
Was interesting to hear today about the annual “SynBio Challenges” competition that has got going in China as a cheaper/free alternative to iGEM - m.synbiochallenges.com/application/...
iCows are coming
November 19, 2025 at 9:33 AM
iCows are coming
Reposted by Martin Holub, Ph.D.
New in Science Magazine from the Doudna Lab and first author Owen Tuck: Recurrent acquisition of nuclease-protease pairs in antiviral immunity. Read here: https://ow.ly/pIWQ50XtEtM
Recurrent acquisition of nuclease-protease pairs in antiviral immunity
Antiviral immune systems diversify by integrating new genes into existing pathways, creating new mechanisms of viral resistance. We identified genes encoding a predicted nuclease paired with a trypsin-like protease repeatedly acquired by multiple, ...
ow.ly
November 18, 2025 at 5:45 PM
New in Science Magazine from the Doudna Lab and first author Owen Tuck: Recurrent acquisition of nuclease-protease pairs in antiviral immunity. Read here: https://ow.ly/pIWQ50XtEtM
Reposted by Martin Holub, Ph.D.
Our microbial-opsin work (and most of the field ) is basic science, but it was intriguing to review clinical progress–direct & indirect–with a wonderful team of co-authors
t.co/JrJen2WGBV
& adapt a fig. of PMID:28912215 (2017) with my long-time collaborator Peter Hegemann (pic: a memory from 2017).
t.co/JrJen2WGBV
& adapt a fig. of PMID:28912215 (2017) with my long-time collaborator Peter Hegemann (pic: a memory from 2017).
November 18, 2025 at 8:52 PM
Our microbial-opsin work (and most of the field ) is basic science, but it was intriguing to review clinical progress–direct & indirect–with a wonderful team of co-authors
t.co/JrJen2WGBV
& adapt a fig. of PMID:28912215 (2017) with my long-time collaborator Peter Hegemann (pic: a memory from 2017).
t.co/JrJen2WGBV
& adapt a fig. of PMID:28912215 (2017) with my long-time collaborator Peter Hegemann (pic: a memory from 2017).
Reposted by Martin Holub, Ph.D.
Join us this Friday 11AM ET for a public briefing about the recommendations & actions needed to prevent biological catastrophe from the G20 High-Level Independent Panel hosted by @nam.edu.
Register here ⬇️
nam.edu/event/closin...
#PandemicPreparedness #GlobalHealthSecurity #G20
Register here ⬇️
nam.edu/event/closin...
#PandemicPreparedness #GlobalHealthSecurity #G20
Closing the Deal: Financing Our Security Against Pandemic Threats public briefing - NAM
Join NAM’s public briefing on new report on pandemic preparedness and global health security. Learn key steps to finance prevention of future health threats.
nam.edu
November 17, 2025 at 4:27 PM
Join us this Friday 11AM ET for a public briefing about the recommendations & actions needed to prevent biological catastrophe from the G20 High-Level Independent Panel hosted by @nam.edu.
Register here ⬇️
nam.edu/event/closin...
#PandemicPreparedness #GlobalHealthSecurity #G20
Register here ⬇️
nam.edu/event/closin...
#PandemicPreparedness #GlobalHealthSecurity #G20
Reposted by Martin Holub, Ph.D.
Remarkable impact: there were no reported cases of #cervicalcancer among women in Scotland who received the #HPV vaccine at the age of 12–13 in the 12 years following vaccination. Here’s a look at studies from around the world that show that #VaccinesWork to #StopCervicalCancer: bit.ly/489S33A
November 17, 2025 at 5:00 PM
Remarkable impact: there were no reported cases of #cervicalcancer among women in Scotland who received the #HPV vaccine at the age of 12–13 in the 12 years following vaccination. Here’s a look at studies from around the world that show that #VaccinesWork to #StopCervicalCancer: bit.ly/489S33A
Reposted by Martin Holub, Ph.D.
🌿 Welche Herausforderungen bringen neue Züchtungstechnologien bei Patenten und Nachweisbarkeit mit sich? Jetzt fürs Webinar vom Forum Genforschung anmelden 👉 geneticresearch.scnat.ch/de/id/shZQ6?...
@bafu.admin.ch
@bafu.admin.ch
November 18, 2025 at 8:00 AM
🌿 Welche Herausforderungen bringen neue Züchtungstechnologien bei Patenten und Nachweisbarkeit mit sich? Jetzt fürs Webinar vom Forum Genforschung anmelden 👉 geneticresearch.scnat.ch/de/id/shZQ6?...
@bafu.admin.ch
@bafu.admin.ch
Reposted by Martin Holub, Ph.D.
Insight into recent goings on at the Ellison Institute of Technology www.ft.com/content/ae2c...
Larry Ellison scales back £10bn Oxford science institute in leadership rift
Trump-supporting billionaire narrows EIT’s ambitions by cutting initiatives and tightening control
www.ft.com
November 18, 2025 at 9:48 AM
Insight into recent goings on at the Ellison Institute of Technology www.ft.com/content/ae2c...
Reposted by Martin Holub, Ph.D.
Preprint: Bacteria sense virus-induced genome degradation via methylated mononucleotides
tinyurl.com/ch3damp
We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity
Revealed by the amazing Ilya Osterman. See his thread below👇
tinyurl.com/ch3damp
We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity
Revealed by the amazing Ilya Osterman. See his thread below👇
November 6, 2025 at 10:39 AM
Preprint: Bacteria sense virus-induced genome degradation via methylated mononucleotides
tinyurl.com/ch3damp
We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity
Revealed by the amazing Ilya Osterman. See his thread below👇
tinyurl.com/ch3damp
We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity
Revealed by the amazing Ilya Osterman. See his thread below👇
