Schlisio_lab
@schlisio-lab.bsky.social
Reposted by Schlisio_lab
Adrenal glia-support cells act as hidden #stemcells that regenerate tissue, but can also initiate adrenal #cancer. A new study in npj Precision Oncology by @schlisio-lab.bsky.social reveals a DLK1-NOTCH switch, deciding whether the cells build healthy tissue or fuel disease 🧪 doi.org/10.1038/s416...
Postnatal sustentacular cells as chromaffin progenitors and tumor cells of origin in VHL-related paragangliomas - npj Precision Oncology
npj Precision Oncology - Postnatal sustentacular cells as chromaffin progenitors and tumor cells of origin in VHL-related paragangliomas
doi.org
October 17, 2025 at 1:04 PM
Adrenal glia-support cells act as hidden #stemcells that regenerate tissue, but can also initiate adrenal #cancer. A new study in npj Precision Oncology by @schlisio-lab.bsky.social reveals a DLK1-NOTCH switch, deciding whether the cells build healthy tissue or fuel disease 🧪 doi.org/10.1038/s416...
Interested in paraganglioma, progenitors, and tumor cells of origin?
Postnatal SOX2⁺ sustentacular glia as chromaffin progenitors can serve as tumor cells of origin in VHL-mutated paragangliomas:
www.researchsquare.com/article/rs-6...
#PPGL #CancerResearch #StemCells #TumorOrigin #SingleCell
Postnatal SOX2⁺ sustentacular glia as chromaffin progenitors can serve as tumor cells of origin in VHL-mutated paragangliomas:
www.researchsquare.com/article/rs-6...
#PPGL #CancerResearch #StemCells #TumorOrigin #SingleCell
Postnatal Sustentacular Cells as Chromaffin Progenitors and Tumor Cells of Origin in VHL-Related Paragangliomas
The cellular source of chromaffin cell regeneration after birth and its relationship to paraganglioma tumorigenesis remains incompletely defined. Here, we identify a postnatal population of SOX2/SOX10...
www.researchsquare.com
July 22, 2025 at 1:06 PM
Interested in paraganglioma, progenitors, and tumor cells of origin?
Postnatal SOX2⁺ sustentacular glia as chromaffin progenitors can serve as tumor cells of origin in VHL-mutated paragangliomas:
www.researchsquare.com/article/rs-6...
#PPGL #CancerResearch #StemCells #TumorOrigin #SingleCell
Postnatal SOX2⁺ sustentacular glia as chromaffin progenitors can serve as tumor cells of origin in VHL-mutated paragangliomas:
www.researchsquare.com/article/rs-6...
#PPGL #CancerResearch #StemCells #TumorOrigin #SingleCell
Reposted by Schlisio_lab
I worked a bit longer on my pink nudibranch video collection resulting from my Okinawa trip (visiting colleagues at OIST). Now the full video is on youtube: youtu.be/-YF9AQxVYS0?...
Cyerce kikutarobabai nudibranch from Okinawa
YouTube video by Igor Adameyko
youtu.be
June 21, 2025 at 11:38 AM
I worked a bit longer on my pink nudibranch video collection resulting from my Okinawa trip (visiting colleagues at OIST). Now the full video is on youtube: youtu.be/-YF9AQxVYS0?...
Reposted by Schlisio_lab
Check out our new study on the innermost nervous system of the body—the submucosal plexus. We define three neuronal classes, map their connectivity, and uncover their stepwise development via phenotypic switching. Congrats to all authors! #NatureNeuroscience #EntericNervousSystem rdcu.be/eoqXz
The transcriptomes, connections and development of submucosal neuron classes in the mouse small intestine
Nature Neuroscience - The neuronal composition of the intestinal submucosal plexus is incompletely understood. Here Li et al. define their neuron classes, connectome and stepwise acquisition of...
rdcu.be
May 29, 2025 at 11:28 AM
Check out our new study on the innermost nervous system of the body—the submucosal plexus. We define three neuronal classes, map their connectivity, and uncover their stepwise development via phenotypic switching. Congrats to all authors! #NatureNeuroscience #EntericNervousSystem rdcu.be/eoqXz
Reposted by Schlisio_lab
1/9 🚀 Our latest findings in
@cp-devcell.bsky.social : #Neuroblastoma cells aren’t locked into one single fate—they flip between developmental programs, driving tumor heterogeneity and malignancy. www.sciencedirect.com/science/arti...
@cp-devcell.bsky.social : #Neuroblastoma cells aren’t locked into one single fate—they flip between developmental programs, driving tumor heterogeneity and malignancy. www.sciencedirect.com/science/arti...
Single-cell MultiOmics and spatial transcriptomics demonstrate neuroblastoma developmental plasticity
Neuroblastoma, the most prevalent extracranial pediatric solid tumor, arises from neural crest progeny cells. It exhibits substantial developmental pl…
www.sciencedirect.com
May 9, 2025 at 10:02 PM
1/9 🚀 Our latest findings in
@cp-devcell.bsky.social : #Neuroblastoma cells aren’t locked into one single fate—they flip between developmental programs, driving tumor heterogeneity and malignancy. www.sciencedirect.com/science/arti...
@cp-devcell.bsky.social : #Neuroblastoma cells aren’t locked into one single fate—they flip between developmental programs, driving tumor heterogeneity and malignancy. www.sciencedirect.com/science/arti...
Painting of the week by my 13-year-old daughter
March 9, 2025 at 2:47 PM
Painting of the week by my 13-year-old daughter
the magic of Aspirin: www.nature.com/articles/s41...
Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity - Nature
Inhibition of cyclooxygenase 1 releases T cells from immunosuppression by platelet-derived thromboxane A2, thereby enhancing the immune response against metastasis.
www.nature.com
March 7, 2025 at 10:12 AM
the magic of Aspirin: www.nature.com/articles/s41...
interesting read: www.economist.com/united-state...
Elon Musk is shredding America’s government as he did Twitter
Some of his operatives are barely out of their teens
www.economist.com
February 13, 2025 at 2:19 PM
interesting read: www.economist.com/united-state...