Scheff Research Lab
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schefflab.bsky.social
Scheff Research Lab
@schefflab.bsky.social
The goal of our research is to investigate whether therapy targeted to peripheral neurons in the cancer microenvironment can alleviate pain and slow tumor progression. https://schefflab.pitt.edu/
#cancerneuroscience #research
2026 Cancer Neuroscience Symposium
Abstract submission deadline: 11.7.2025
This is one of my favorite meetings of the year where all the science is really great and so much collaboration that starts within those couple days. Even if you're on a cusp of the field, totally worth checking out!
October 22, 2025 at 1:02 PM
The NOA has landed! We have our first 🛏️to 🔬 to🛌translation! In collaboration with Glycyx Therapeutics, we received funding for a multi-institutional clinical trial to test if peripheral acting OPRM1 antagonism can improve response to immune checkpoint blockade in head and neck cancer patients!
September 23, 2025 at 10:26 PM
The Scheff Lab image was selected to be the background of the @pcpr-pittpain.bsky.social seminar series poster highlighting mammary innervating dorsal root ganglia neurons. This image was taken in a study understanding the impact of sensory neurons on breast cancer progression and (lack of) pain.
August 19, 2025 at 1:11 PM
Thank to #RushtoCrush for a great weekend raising funds for #cancer #research!
May 21, 2025 at 3:26 PM
🎉Congratulations to @andremartel.bsky.social for winning BEST POSTER at yesterday's #painday, held at the University of Pittsburgh @cnup.bsky.social! Thanks to Hannah and @nehamokhasi.bsky.social for their excellent contributions.
May 8, 2025 at 3:41 PM
Thanks to @usasp.bsky.social for a great conference! Dr Scheff discussed reverse translation in #cancerpain and presented a poster detailing new work on radiation-induced pain and oral mucositis. @andremartel.bsky.social presented updates on his project on sympathetics and cancer pain. #research
May 6, 2025 at 6:53 PM
@andremartel.bsky.social and I had an awesome time teaching at the inaugural Cold Spring Harbor Laboratory 2025 Methods in Cancer Neuroscience course this week! #cshl #cancerneuroscience. Wish we could have stayed but had to be home for the Stand Up For Science Event! @standupforscience.bsky.social
March 7, 2025 at 3:35 PM
📢New publication out: Sensory Neurotransmission and Pain in Solid Tumor Progression! This review article by first author @andremartel.bsky.social details recent work on the bidirectional relationship between sensory neurons and #cancer cells.
authors.elsevier.com/sd/article/S...

#neurobiology
January 30, 2025 at 2:29 PM
📢Check out our new publication, Morphine treatment restricts response to immunotherapy in oral squamous cell carcinoma, out now in the Journal for ImmunoTherapy of Cancer! This article presents urgent work with implications for improving ICI therapy responses. jitc.bmj.com/content/12/1...
November 21, 2024 at 6:33 PM