Stuart Campbell
@sc345.bsky.social
MD training in Infectious Diseases splitting time between Brisbane & Darwin, Australia.
🏈: GC Suns (AFL)
⚽︎: LFC (EPL)
🏏: Strikers (BBL) & Aus (Int)
🏈: GC Suns (AFL)
⚽︎: LFC (EPL)
🏏: Strikers (BBL) & Aus (Int)
Quite looking forward to this week's intrepid teaching #ozbug ID/Immuno/Rheum/Heam panel discussion on PUO, quite a cool topic & way to chat about it!
July 21, 2025 at 11:16 AM
Quite looking forward to this week's intrepid teaching #ozbug ID/Immuno/Rheum/Heam panel discussion on PUO, quite a cool topic & way to chat about it!
First time trying black sapote. Wasn't sure about it and didn't want to make a full smoothie so went crumpet and some double cream, it was quite good.
June 21, 2025 at 3:53 AM
First time trying black sapote. Wasn't sure about it and didn't want to make a full smoothie so went crumpet and some double cream, it was quite good.
More #Qfever #onehealth - Prof L Epelboin talks about the French Guiana experience.
🌎 Highest rates (~30/100k yearly) globally
😷 Driven by virulent MST17 strain
🧢 QF causes 25% of CAP in Cayenne & worst in E
euro. ethnic.
🦥 Outbreaks linked to sloths and capybara
#qfig #IDsky @qfig.bsky.social
🌎 Highest rates (~30/100k yearly) globally
😷 Driven by virulent MST17 strain
🧢 QF causes 25% of CAP in Cayenne & worst in E
euro. ethnic.
🦥 Outbreaks linked to sloths and capybara
#qfig #IDsky @qfig.bsky.social
June 15, 2025 at 11:10 AM
More #Qfever #onehealth - Prof L Epelboin talks about the French Guiana experience.
🌎 Highest rates (~30/100k yearly) globally
😷 Driven by virulent MST17 strain
🧢 QF causes 25% of CAP in Cayenne & worst in E
euro. ethnic.
🦥 Outbreaks linked to sloths and capybara
#qfig #IDsky @qfig.bsky.social
🌎 Highest rates (~30/100k yearly) globally
😷 Driven by virulent MST17 strain
🧢 QF causes 25% of CAP in Cayenne & worst in E
euro. ethnic.
🦥 Outbreaks linked to sloths and capybara
#qfig #IDsky @qfig.bsky.social
Next up at the #QFIG, Dr R Norton outlines some ➕ & ➖ 4 controversies in #qfever:
🩸Monitoring & Rx of elevated ph 1 IgG w/ no sx.
🚱 Post acute monitoring w/ pros valves
🔍 Role of routine TTE in acute QF follow up
💊 Role for HCQ combo Rx with doxy for Rx of QF endocarditis
Split opinions!
#idsky
🩸Monitoring & Rx of elevated ph 1 IgG w/ no sx.
🚱 Post acute monitoring w/ pros valves
🔍 Role of routine TTE in acute QF follow up
💊 Role for HCQ combo Rx with doxy for Rx of QF endocarditis
Split opinions!
#idsky
June 14, 2025 at 3:37 AM
The pictures I forgot to attach
June 5, 2025 at 4:21 AM
The pictures I forgot to attach
Prof M Good & A/Prof M Pandey close #LISSSD25 thanking all the local committee, scientific advisory committee (led by Dr
T Lamagni & @joshosowicki.bsky.social), presenters, and delegates.
Prof A Steer announces #LISSSD28 is to be held in
📌 Limassol, Cyprus 🇨🇾 2028
T Lamagni & @joshosowicki.bsky.social), presenters, and delegates.
Prof A Steer announces #LISSSD28 is to be held in
📌 Limassol, Cyprus 🇨🇾 2028
June 5, 2025 at 4:20 AM
Prof M Good & A/Prof M Pandey close #LISSSD25 thanking all the local committee, scientific advisory committee (led by Dr
T Lamagni & @joshosowicki.bsky.social), presenters, and delegates.
Prof A Steer announces #LISSSD28 is to be held in
📌 Limassol, Cyprus 🇨🇾 2028
T Lamagni & @joshosowicki.bsky.social), presenters, and delegates.
Prof A Steer announces #LISSSD28 is to be held in
📌 Limassol, Cyprus 🇨🇾 2028
Prof M Voysey presents some prelim results of a prospective GBS infect. cohort
🧮 101 early & 67 late iGBS vs 286 GBS colonised but not infected ctrl
🚼 Birth weight of late < early < ctrl
3️⃣ Serotype III most common, esp in late onset dis.
#LISSSD25 #gbs #clinmicro
🧮 101 early & 67 late iGBS vs 286 GBS colonised but not infected ctrl
🚼 Birth weight of late < early < ctrl
3️⃣ Serotype III most common, esp in late onset dis.
#LISSSD25 #gbs #clinmicro
June 5, 2025 at 3:53 AM
Prof M Voysey presents some prelim results of a prospective GBS infect. cohort
🧮 101 early & 67 late iGBS vs 286 GBS colonised but not infected ctrl
🚼 Birth weight of late < early < ctrl
3️⃣ Serotype III most common, esp in late onset dis.
#LISSSD25 #gbs #clinmicro
🧮 101 early & 67 late iGBS vs 286 GBS colonised but not infected ctrl
🚼 Birth weight of late < early < ctrl
3️⃣ Serotype III most common, esp in late onset dis.
#LISSSD25 #gbs #clinmicro
Outcomes:
ISAAC - Strep A carriage at d14
STRAP - Days alive & out of hospital at d30
ISAAC - Strep A carriage at d14
STRAP - Days alive & out of hospital at d30
June 5, 2025 at 1:29 AM
Outcomes:
ISAAC - Strep A carriage at d14
STRAP - Days alive & out of hospital at d30
ISAAC - Strep A carriage at d14
STRAP - Days alive & out of hospital at d30
Dr K Gibney flys the flag for 🦘 clin trials by 🎺
ISAAC 🔎 at Abx prophylaxis of close iGAS contacts (enrolling soon)
STRAP 🔎 backbone Abx, adjunctive Abx, and IVIg (enrolling 2026ish)
Only enrolling in Aus for now but looking for int. collab.
#LISSSD25 #idsky #clinicaltrials #strep
ISAAC 🔎 at Abx prophylaxis of close iGAS contacts (enrolling soon)
STRAP 🔎 backbone Abx, adjunctive Abx, and IVIg (enrolling 2026ish)
Only enrolling in Aus for now but looking for int. collab.
#LISSSD25 #idsky #clinicaltrials #strep
June 5, 2025 at 1:24 AM
Dr K Gibney flys the flag for 🦘 clin trials by 🎺
ISAAC 🔎 at Abx prophylaxis of close iGAS contacts (enrolling soon)
STRAP 🔎 backbone Abx, adjunctive Abx, and IVIg (enrolling 2026ish)
Only enrolling in Aus for now but looking for int. collab.
#LISSSD25 #idsky #clinicaltrials #strep
ISAAC 🔎 at Abx prophylaxis of close iGAS contacts (enrolling soon)
STRAP 🔎 backbone Abx, adjunctive Abx, and IVIg (enrolling 2026ish)
Only enrolling in Aus for now but looking for int. collab.
#LISSSD25 #idsky #clinicaltrials #strep
Dr O Xie has an entertaining talk on S. dys subsp eq [SDSE]
🐴 iSDSE has similar incidence and mortality v iGAS
🐎 Less genomic clustering in SDSE
🫏 Global dissemination iSDSE driven by stG62647-lineage
#LISSSD25 #clinmicro #idsky
🐴 iSDSE has similar incidence and mortality v iGAS
🐎 Less genomic clustering in SDSE
🫏 Global dissemination iSDSE driven by stG62647-lineage
#LISSSD25 #clinmicro #idsky
June 5, 2025 at 12:59 AM
Dr O Xie has an entertaining talk on S. dys subsp eq [SDSE]
🐴 iSDSE has similar incidence and mortality v iGAS
🐎 Less genomic clustering in SDSE
🫏 Global dissemination iSDSE driven by stG62647-lineage
#LISSSD25 #clinmicro #idsky
🐴 iSDSE has similar incidence and mortality v iGAS
🐎 Less genomic clustering in SDSE
🫏 Global dissemination iSDSE driven by stG62647-lineage
#LISSSD25 #clinmicro #idsky
PhD cand. J Iwasaki talks about mechanism behind strep throat recurrence.
👅 ~15% strep throat relapse
👅 Relapse strains can persist in ⬆️ [pen]
👅 Intracellular persistence in strep intracell. comm. [SIC]
👅 SICs are L-switch'd to lack cell wall hence recur post Pen Rx
#LISSSD25 #clinmicro
👅 ~15% strep throat relapse
👅 Relapse strains can persist in ⬆️ [pen]
👅 Intracellular persistence in strep intracell. comm. [SIC]
👅 SICs are L-switch'd to lack cell wall hence recur post Pen Rx
#LISSSD25 #clinmicro
June 4, 2025 at 5:47 AM
PhD cand. J Iwasaki talks about mechanism behind strep throat recurrence.
👅 ~15% strep throat relapse
👅 Relapse strains can persist in ⬆️ [pen]
👅 Intracellular persistence in strep intracell. comm. [SIC]
👅 SICs are L-switch'd to lack cell wall hence recur post Pen Rx
#LISSSD25 #clinmicro
👅 ~15% strep throat relapse
👅 Relapse strains can persist in ⬆️ [pen]
👅 Intracellular persistence in strep intracell. comm. [SIC]
👅 SICs are L-switch'd to lack cell wall hence recur post Pen Rx
#LISSSD25 #clinmicro
Another AUROC: L Carlton presents a possible ARF biomarker id'd from a series of bead array exp using START cohort samples.
Most accurate candidate TRAFIP with AUROC 0.79 solo or upto 0.845 in combo w/ other biomarkers.
Coming to a revised-revised Jones criteria? #LISSSD25 #idsky
Most accurate candidate TRAFIP with AUROC 0.79 solo or upto 0.845 in combo w/ other biomarkers.
Coming to a revised-revised Jones criteria? #LISSSD25 #idsky
June 4, 2025 at 3:13 AM
Prof N Ketheesan outlines his labs use of the Lewis rat model to explore RHD/ARF.
🐀 rM5 protein induces carditis & myocarditis, PR sensitive test
🐀 Sera & Tcells transfused to nin-exposed replicate disease.
🐀 Repeated exposures result in RHD phenotype w/ varied ab response.
#LISSSD25
🐀 rM5 protein induces carditis & myocarditis, PR sensitive test
🐀 Sera & Tcells transfused to nin-exposed replicate disease.
🐀 Repeated exposures result in RHD phenotype w/ varied ab response.
#LISSSD25
June 4, 2025 at 1:17 AM
Prof N Ketheesan outlines his labs use of the Lewis rat model to explore RHD/ARF.
🐀 rM5 protein induces carditis & myocarditis, PR sensitive test
🐀 Sera & Tcells transfused to nin-exposed replicate disease.
🐀 Repeated exposures result in RHD phenotype w/ varied ab response.
#LISSSD25
🐀 rM5 protein induces carditis & myocarditis, PR sensitive test
🐀 Sera & Tcells transfused to nin-exposed replicate disease.
🐀 Repeated exposures result in RHD phenotype w/ varied ab response.
#LISSSD25
Dr K Doran presents interactions between C alb & GBS in the vaginal tract w/ some nifty models and clinical datasets
🦠 GBS & C alb increased in vaginal dysbiosis
🦠 C alb forms biofilm & GBS colonises
🦠 In the biofilm GBS is more antibiotic resistant & virulent (CovR)
#LISSSD25 #clinmicro
🦠 GBS & C alb increased in vaginal dysbiosis
🦠 C alb forms biofilm & GBS colonises
🦠 In the biofilm GBS is more antibiotic resistant & virulent (CovR)
#LISSSD25 #clinmicro
June 3, 2025 at 1:53 AM
Dr K Doran presents interactions between C alb & GBS in the vaginal tract w/ some nifty models and clinical datasets
🦠 GBS & C alb increased in vaginal dysbiosis
🦠 C alb forms biofilm & GBS colonises
🦠 In the biofilm GBS is more antibiotic resistant & virulent (CovR)
#LISSSD25 #clinmicro
🦠 GBS & C alb increased in vaginal dysbiosis
🦠 C alb forms biofilm & GBS colonises
🦠 In the biofilm GBS is more antibiotic resistant & virulent (CovR)
#LISSSD25 #clinmicro
Dr K Roberts & H Jones introduce the TREAT-SC trial - oral dex vs placebo for the management of Sydenham's chorea in children.
🌎 Multi site across Aus & NZ
anzctr.org.au/Trial/Registration/TrialReview.aspx?id=22234&isClinicalTrial=True
🌎 Multi site across Aus & NZ
anzctr.org.au/Trial/Registration/TrialReview.aspx?id=22234&isClinicalTrial=True
June 2, 2025 at 5:58 AM
Dr K Roberts & H Jones introduce the TREAT-SC trial - oral dex vs placebo for the management of Sydenham's chorea in children.
🌎 Multi site across Aus & NZ
anzctr.org.au/Trial/Registration/TrialReview.aspx?id=22234&isClinicalTrial=True
🌎 Multi site across Aus & NZ
anzctr.org.au/Trial/Registration/TrialReview.aspx?id=22234&isClinicalTrial=True
A/Prof A Anderson talks about her qualitative research into Strep A vaccination
🗝️ 80x rates of ARF in some NZ groups
🗝️ ARF viewed as ongoing effect of colonisation
🗝️ Strep A vac a good thing (even 4 prochoice)
🗝️ Whanau (family) centric approach for consent and delivery
#LISSSD25 #idsky #strepA
🗝️ 80x rates of ARF in some NZ groups
🗝️ ARF viewed as ongoing effect of colonisation
🗝️ Strep A vac a good thing (even 4 prochoice)
🗝️ Whanau (family) centric approach for consent and delivery
#LISSSD25 #idsky #strepA
June 2, 2025 at 5:12 AM