Sara França
@sarassfranca.bsky.social
Biomedical Scientist interested in #Cancer #Metastasis Research | PhD applicant | Looking for Research Assistant positions in the US
https://www.linkedin.com/in/sara-susan-silva-de-fran%C3%A7a-140204204?trk=contact-info
https://www.linkedin.com/in/sara-susan-silva-de-fran%C3%A7a-140204204?trk=contact-info
Reposted by Sara França
The CDI announces the launch of the Cancer Dormancy Institute Service Core. The Core provides expert advice on markers, mouse, avian and 3D models, protocol development and rare cell isolation methods to explore dormancy, MRD & relapse biology across cancers.
montefioreeinstein.org/cancer/resea...
montefioreeinstein.org/cancer/resea...
Cancer Dormancy Institute Service Core | Montefiore Einstein Comprehensive Cancer Center | Patient Care | Montefiore Einstein
Support your cancer dormancy research with expert models, markers, and protocols from Montefiore Einstein’s Cancer Dormancy Institute Service Core.
montefioreeinstein.org
May 29, 2025 at 7:12 PM
The CDI announces the launch of the Cancer Dormancy Institute Service Core. The Core provides expert advice on markers, mouse, avian and 3D models, protocol development and rare cell isolation methods to explore dormancy, MRD & relapse biology across cancers.
montefioreeinstein.org/cancer/resea...
montefioreeinstein.org/cancer/resea...
✨Most of us learn how to design experiments.
But how often are we taught to synthesize what already exists?
I’ve recently been exploring #SystematicReview of preclinical studies, and I truly believe more researchers should too.
Here’s why…
🧵1/7
#SysRev #academia #AI #phdlife
But how often are we taught to synthesize what already exists?
I’ve recently been exploring #SystematicReview of preclinical studies, and I truly believe more researchers should too.
Here’s why…
🧵1/7
#SysRev #academia #AI #phdlife
May 22, 2025 at 3:30 PM
✨Most of us learn how to design experiments.
But how often are we taught to synthesize what already exists?
I’ve recently been exploring #SystematicReview of preclinical studies, and I truly believe more researchers should too.
Here’s why…
🧵1/7
#SysRev #academia #AI #phdlife
But how often are we taught to synthesize what already exists?
I’ve recently been exploring #SystematicReview of preclinical studies, and I truly believe more researchers should too.
Here’s why…
🧵1/7
#SysRev #academia #AI #phdlife
📢 Collection of Articles on #Metastasis & #TME (02.18.2025 – 02.27.2025)
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop relevant papers I might have missed in the comments!
#Cancer #oncology #Immunology #ScienceDay #Health #NIH #Science #SaraMetastasisUpdates
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop relevant papers I might have missed in the comments!
#Cancer #oncology #Immunology #ScienceDay #Health #NIH #Science #SaraMetastasisUpdates
March 1, 2025 at 1:16 AM
📢 Collection of Articles on #Metastasis & #TME (02.18.2025 – 02.27.2025)
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop relevant papers I might have missed in the comments!
#Cancer #oncology #Immunology #ScienceDay #Health #NIH #Science #SaraMetastasisUpdates
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop relevant papers I might have missed in the comments!
#Cancer #oncology #Immunology #ScienceDay #Health #NIH #Science #SaraMetastasisUpdates
1/ Metastasis can stay dormant for years before reactivating and becoming lethal. But what wakes them up? A new study uncovers a fascinating mechanism involving epigenetics and immune suppression. Let’s break it down! 🧵
#metastasis #cancer #oncology #science #Immunology #dormancy
#metastasis #cancer #oncology #science #Immunology #dormancy
February 26, 2025 at 8:41 PM
1/ Metastasis can stay dormant for years before reactivating and becoming lethal. But what wakes them up? A new study uncovers a fascinating mechanism involving epigenetics and immune suppression. Let’s break it down! 🧵
#metastasis #cancer #oncology #science #Immunology #dormancy
#metastasis #cancer #oncology #science #Immunology #dormancy
Reposted by Sara França
We're pleased to announce the next webinar from our Early Career Leadership Council.
Join us on March 4th to hear from Dr Ashley Laughney on "Tackling the genotype-to-phenotype problem in cancer evolution"
Sign up here → us02web.zoom.us/webinar/regi... ←
Join us on March 4th to hear from Dr Ashley Laughney on "Tackling the genotype-to-phenotype problem in cancer evolution"
Sign up here → us02web.zoom.us/webinar/regi... ←
February 20, 2025 at 3:09 AM
We're pleased to announce the next webinar from our Early Career Leadership Council.
Join us on March 4th to hear from Dr Ashley Laughney on "Tackling the genotype-to-phenotype problem in cancer evolution"
Sign up here → us02web.zoom.us/webinar/regi... ←
Join us on March 4th to hear from Dr Ashley Laughney on "Tackling the genotype-to-phenotype problem in cancer evolution"
Sign up here → us02web.zoom.us/webinar/regi... ←
📢 Collection of Articles on Metastasis & TME (02.10.2025 – 02.17.2025)
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments!📝
#Cancer #Research #Metastasis #TME #academicsky #oncology #SaraMetastasisUpdates
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments!📝
#Cancer #Research #Metastasis #TME #academicsky #oncology #SaraMetastasisUpdates
February 18, 2025 at 6:43 PM
📢 Collection of Articles on Metastasis & TME (02.10.2025 – 02.17.2025)
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments!📝
#Cancer #Research #Metastasis #TME #academicsky #oncology #SaraMetastasisUpdates
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments!📝
#Cancer #Research #Metastasis #TME #academicsky #oncology #SaraMetastasisUpdates
Practicing a surgical technique to study metastasis🔬🐭
🧵1/ I’m practicing a technique used for intravital imaging, which allows us to track tumor cells as they invade, disseminate, and survive in distant organs. A game-changer for #metastasis #research. Thanks Dr. @dentenberg.bsky.social!
#cancer
🧵1/ I’m practicing a technique used for intravital imaging, which allows us to track tumor cells as they invade, disseminate, and survive in distant organs. A game-changer for #metastasis #research. Thanks Dr. @dentenberg.bsky.social!
#cancer
February 16, 2025 at 7:36 PM
Practicing a surgical technique to study metastasis🔬🐭
🧵1/ I’m practicing a technique used for intravital imaging, which allows us to track tumor cells as they invade, disseminate, and survive in distant organs. A game-changer for #metastasis #research. Thanks Dr. @dentenberg.bsky.social!
#cancer
🧵1/ I’m practicing a technique used for intravital imaging, which allows us to track tumor cells as they invade, disseminate, and survive in distant organs. A game-changer for #metastasis #research. Thanks Dr. @dentenberg.bsky.social!
#cancer
Reposted by Sara França
Blood clots form due to signals from the lungs of #cancer patients — not from other organs, according to a new study by MSK, @weillcornell.bsky.social, UC San Diego Health. The study could help develop new tests and treatments for high-risk patients, MSK’s Dr. Jacqueline Bromberg says.
Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2
Cancer-associated thrombosis is a leading cause of mortality. Lucotti et al. uncover
the formation of a pro-thrombotic niche in the non-metastatic lung microenvironment
that promotes thrombosis and me...
www.cell.com
February 12, 2025 at 4:37 PM
Blood clots form due to signals from the lungs of #cancer patients — not from other organs, according to a new study by MSK, @weillcornell.bsky.social, UC San Diego Health. The study could help develop new tests and treatments for high-risk patients, MSK’s Dr. Jacqueline Bromberg says.
📢 Collection of Articles on Metastasis & TME (02.02.2025 – 02.09.2025)
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments!📝
#CancerResearch #Metastasis #TME #SaraMetastasisUpdates
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments!📝
#CancerResearch #Metastasis #TME #SaraMetastasisUpdates
February 10, 2025 at 5:57 PM
📢 Collection of Articles on Metastasis & TME (02.02.2025 – 02.09.2025)
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments!📝
#CancerResearch #Metastasis #TME #SaraMetastasisUpdates
🔍Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments!📝
#CancerResearch #Metastasis #TME #SaraMetastasisUpdates
📢 Collection of Articles on Metastasis & TME (01.26.2025 – 02.01.2025)
🔍 Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments! 📝
#CancerResearch #Metastasis #TumorMicroenvironment #SaraMetastasisUpdates
🔍 Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments! 📝
#CancerResearch #Metastasis #TumorMicroenvironment #SaraMetastasisUpdates
February 2, 2025 at 12:10 AM
📢 Collection of Articles on Metastasis & TME (01.26.2025 – 02.01.2025)
🔍 Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments! 📝
#CancerResearch #Metastasis #TumorMicroenvironment #SaraMetastasisUpdates
🔍 Check the image for titles & numbers, and find the links below:
Feel free to drop any relevant papers I might have missed in the comments! 📝
#CancerResearch #Metastasis #TumorMicroenvironment #SaraMetastasisUpdates
Congrats on this exciting work Dr. @dentenberg.bsky.social and all the team! The impact of NAC on macrophage polarization and metastasis adds a crucial dimension to therapy response. Curious to dive into the preprint, understanding how targeting Notch could mitigate these effects is intriguing!
Super excited to share the latest work by the amazing Madeline DeLuca-Friedman, now out as a preprint on @BioRxiv!
What's it all about? Keep reading!
www.biorxiv.org/content/10.1...
@cdi-einstein.bsky.social
@einsteinmededu.bsky.social
@monteeinsteinpath.bsky.social
What's it all about? Keep reading!
www.biorxiv.org/content/10.1...
@cdi-einstein.bsky.social
@einsteinmededu.bsky.social
@monteeinsteinpath.bsky.social
Paclitaxel causes de novo induction of invasive breast cancer cells by repolarizing tumor-associated macrophages
Background Metastasis is the leading cause of breast cancer (BC) death, and tumor cells must migrate and invade to metastasize. BC cells that express the pro-metastatic actin regulatory protein MenaIN...
www.biorxiv.org
February 1, 2025 at 6:41 PM
Congrats on this exciting work Dr. @dentenberg.bsky.social and all the team! The impact of NAC on macrophage polarization and metastasis adds a crucial dimension to therapy response. Curious to dive into the preprint, understanding how targeting Notch could mitigate these effects is intriguing!
Reposted by Sara França
Super excited to share the latest work by the amazing Madeline DeLuca-Friedman, now out as a preprint on @BioRxiv!
What's it all about? Keep reading!
www.biorxiv.org/content/10.1...
@cdi-einstein.bsky.social
@einsteinmededu.bsky.social
@monteeinsteinpath.bsky.social
What's it all about? Keep reading!
www.biorxiv.org/content/10.1...
@cdi-einstein.bsky.social
@einsteinmededu.bsky.social
@monteeinsteinpath.bsky.social
Paclitaxel causes de novo induction of invasive breast cancer cells by repolarizing tumor-associated macrophages
Background Metastasis is the leading cause of breast cancer (BC) death, and tumor cells must migrate and invade to metastasize. BC cells that express the pro-metastatic actin regulatory protein MenaIN...
www.biorxiv.org
February 1, 2025 at 5:22 PM
Super excited to share the latest work by the amazing Madeline DeLuca-Friedman, now out as a preprint on @BioRxiv!
What's it all about? Keep reading!
www.biorxiv.org/content/10.1...
@cdi-einstein.bsky.social
@einsteinmededu.bsky.social
@monteeinsteinpath.bsky.social
What's it all about? Keep reading!
www.biorxiv.org/content/10.1...
@cdi-einstein.bsky.social
@einsteinmededu.bsky.social
@monteeinsteinpath.bsky.social
Thanks to @jacksonlab.bsky.social for the valuable webinar on immunodeficient mouse models! From Nude to NSG, each strain offers distinct immunodeficiency levels, shaping cancer and immunity research. Choosing the right model is essential for translational success! #CancerResearch #Immunology
January 30, 2025 at 8:56 PM
Thanks to @jacksonlab.bsky.social for the valuable webinar on immunodeficient mouse models! From Nude to NSG, each strain offers distinct immunodeficiency levels, shaping cancer and immunity research. Choosing the right model is essential for translational success! #CancerResearch #Immunology
🔬 Metastatic Breast Cancer: Are We Truly Advancing?
Yesterday, I attended an insightful talk by Dr. @stolaney1.bsky.social from @danafarber.bsky.social on the latest treatments for ER+ MBC. And my conclusions were… While research reveals complex tumor phenotypes, single-cell profiles, and... (1/5)
Yesterday, I attended an insightful talk by Dr. @stolaney1.bsky.social from @danafarber.bsky.social on the latest treatments for ER+ MBC. And my conclusions were… While research reveals complex tumor phenotypes, single-cell profiles, and... (1/5)
January 30, 2025 at 8:14 PM
🔬 Metastatic Breast Cancer: Are We Truly Advancing?
Yesterday, I attended an insightful talk by Dr. @stolaney1.bsky.social from @danafarber.bsky.social on the latest treatments for ER+ MBC. And my conclusions were… While research reveals complex tumor phenotypes, single-cell profiles, and... (1/5)
Yesterday, I attended an insightful talk by Dr. @stolaney1.bsky.social from @danafarber.bsky.social on the latest treatments for ER+ MBC. And my conclusions were… While research reveals complex tumor phenotypes, single-cell profiles, and... (1/5)
Reposted by Sara França
Check out the revised version of our latest study on uveal melanoma dormancy mechanisms. One year of additional work led by Rama Kadamb in my lab and in collaboration with Andrew Aplin's lab at Thomas Jefferson University. Congrats to all that worked on this paper! www.biorxiv.org/content/10.1...
Lineage commitment pathways epigenetically oppose oncogenic Gαq/11-YAP signaling in dormant disseminated uveal melanoma
Uveal melanoma (UM) can remain in clinical dormancy for decades only to later produce lethal metastases. Using Gαq/11mut/BAP1wt UM xenograft models and human metastatic samples, we identified NR2F1 as...
www.biorxiv.org
January 29, 2025 at 2:01 PM
Check out the revised version of our latest study on uveal melanoma dormancy mechanisms. One year of additional work led by Rama Kadamb in my lab and in collaboration with Andrew Aplin's lab at Thomas Jefferson University. Congrats to all that worked on this paper! www.biorxiv.org/content/10.1...
Reposted by Sara França
Thrilled our review was selected as a #science #highlight in this #Cell timeline of the last decade 🧪
"Embracing #cancer complexity: Hallmarks of systemic disease"
Swanton et al, 2024
www.sciencedirect.com/science/arti...
@charlesswanton.bsky.social
@cancerresearchuk.org
@cp-cell.bsky.social
"Embracing #cancer complexity: Hallmarks of systemic disease"
Swanton et al, 2024
www.sciencedirect.com/science/arti...
@charlesswanton.bsky.social
@cancerresearchuk.org
@cp-cell.bsky.social
January 27, 2025 at 1:00 PM
Thrilled our review was selected as a #science #highlight in this #Cell timeline of the last decade 🧪
"Embracing #cancer complexity: Hallmarks of systemic disease"
Swanton et al, 2024
www.sciencedirect.com/science/arti...
@charlesswanton.bsky.social
@cancerresearchuk.org
@cp-cell.bsky.social
"Embracing #cancer complexity: Hallmarks of systemic disease"
Swanton et al, 2024
www.sciencedirect.com/science/arti...
@charlesswanton.bsky.social
@cancerresearchuk.org
@cp-cell.bsky.social
✨ Certificates from 2020, but lessons for a lifetime! ✨
Today, I want to share two courses that shaped my journey: "Introduction to the Biology of Cancer" and "Understanding Cancer Metastasis". Through them, I discovered my true path in research. 🧵1/4
#Research #Cancer #Metastasis #AcademicSky
Today, I want to share two courses that shaped my journey: "Introduction to the Biology of Cancer" and "Understanding Cancer Metastasis". Through them, I discovered my true path in research. 🧵1/4
#Research #Cancer #Metastasis #AcademicSky
January 27, 2025 at 5:17 PM
✨ Certificates from 2020, but lessons for a lifetime! ✨
Today, I want to share two courses that shaped my journey: "Introduction to the Biology of Cancer" and "Understanding Cancer Metastasis". Through them, I discovered my true path in research. 🧵1/4
#Research #Cancer #Metastasis #AcademicSky
Today, I want to share two courses that shaped my journey: "Introduction to the Biology of Cancer" and "Understanding Cancer Metastasis". Through them, I discovered my true path in research. 🧵1/4
#Research #Cancer #Metastasis #AcademicSky
Hello, Academic X! I'm Sara, a Brazilian researcher passionate about studying #cancer #metastasis, especially its mechanisms, #dormancy, and the #TumorMicroenvironment. I have experience in stress responses, in vivo models, and various molecular techniques. 🧵1/4
January 26, 2025 at 11:59 PM
Hello, Academic X! I'm Sara, a Brazilian researcher passionate about studying #cancer #metastasis, especially its mechanisms, #dormancy, and the #TumorMicroenvironment. I have experience in stress responses, in vivo models, and various molecular techniques. 🧵1/4
Reposted by Sara França
Getting in on the starter pack game for folks focusing on studying tumor-immune interactions during metastasis — DM/comment if you want to be added!
go.bsky.app/GyZxUDH
go.bsky.app/GyZxUDH
November 21, 2024 at 6:28 PM
Getting in on the starter pack game for folks focusing on studying tumor-immune interactions during metastasis — DM/comment if you want to be added!
go.bsky.app/GyZxUDH
go.bsky.app/GyZxUDH