Sandra GL
@sandra-gl.bsky.social
Stem Cell Biology & Early Cancer Research, UCL
Pinned
Sandra GL
@sandra-gl.bsky.social
· May 2
www.science.org
Our work describing the biological mechanisms driving the formation of a cancerized field in the airways is now out @science.org!
Huge team effort from @lungs4living.bsky.social and amazing collaborators to delineate the origin of precancerous lung disease 🫁
www.science.org/doi/full/10....
Huge team effort from @lungs4living.bsky.social and amazing collaborators to delineate the origin of precancerous lung disease 🫁
www.science.org/doi/full/10....
Reposted by Sandra GL
Looking forward to working with new colleagues on a collaborative project in lung disease modelling and transcriptomics - please share! And email Jenny @jennydickens41.bsky.social, or me, with any questions. 😀
www.jobs.cam.ac.uk/job/52936/
www.jobs.cam.ac.uk/job/52936/
Research Associate: Human Lung Disease Mechanisms (Fixed Term) - Job Opportunities - University of Cambridge
Research Associate: Human Lung Disease Mechanisms (Fixed Term) in the Gurdon Institute at the University of Cambridge.
www.jobs.cam.ac.uk
October 2, 2025 at 3:14 PM
Looking forward to working with new colleagues on a collaborative project in lung disease modelling and transcriptomics - please share! And email Jenny @jennydickens41.bsky.social, or me, with any questions. 😀
www.jobs.cam.ac.uk/job/52936/
www.jobs.cam.ac.uk/job/52936/
Reposted by Sandra GL
Nature research paper: Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer
go.nature.com/3ViRTAP
go.nature.com/3ViRTAP
Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer - Nature
Basal cells, rather than neuroendocrine cells, have been identified as the probable origin of small cell lung cancer and other neuroendocrine–tuft cancers, explaining neuroendocrine–tuft heterogeneity and offering new perspectives for targeting lineage plasticity.
go.nature.com
September 24, 2025 at 12:48 PM
Nature research paper: Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer
go.nature.com/3ViRTAP
go.nature.com/3ViRTAP
Reposted by Sandra GL
My main PhD project is now up on bioRxiv! If you’re interested in somatic evolution or machine learning for simulation-based inference, read on…
doi.org/10.1101/2025...
[1/15]
doi.org/10.1101/2025...
[1/15]
Recovery of human upper airway epithelium after smoking cessation is driven by a slow-cycling stem cell population and immune surveillance
The upper airway epithelium in humans is maintained in homeostasis by a resident population of basal stem cells. In the presence of tobacco smoke these gain mutations that significantly increase their...
doi.org
September 3, 2025 at 1:04 PM
My main PhD project is now up on bioRxiv! If you’re interested in somatic evolution or machine learning for simulation-based inference, read on…
doi.org/10.1101/2025...
[1/15]
doi.org/10.1101/2025...
[1/15]
Reposted by Sandra GL
🚨 PhD Position available in our lab 🚨 exploring the power of blood immune multi-omics to detect lung cancer years prior to clinical diagnosis in a unique cohort of >10,000 CT screened individuals.
✅ Wet & dry lab
✅ September 2025 enrolment
✅ UK tuition fees only
www.ucl.ac.uk/medical-scie...
✅ Wet & dry lab
✅ September 2025 enrolment
✅ UK tuition fees only
www.ucl.ac.uk/medical-scie...
Pre-Cancer Immunology
The Pre-Cancer Immunology Lab (James Reading Lab) is mapping pre-invasive T cell dynamics during carcinogenesis to detect and intercept cancer development.
www.ucl.ac.uk
August 5, 2025 at 5:57 PM
🚨 PhD Position available in our lab 🚨 exploring the power of blood immune multi-omics to detect lung cancer years prior to clinical diagnosis in a unique cohort of >10,000 CT screened individuals.
✅ Wet & dry lab
✅ September 2025 enrolment
✅ UK tuition fees only
www.ucl.ac.uk/medical-scie...
✅ Wet & dry lab
✅ September 2025 enrolment
✅ UK tuition fees only
www.ucl.ac.uk/medical-scie...
Reposted by Sandra GL
The ‘cell of origin’ of the second most common lung cancer and how it becomes dominant in the lung have been discovered, in a new study led by Prof Sam Janes & Dr Sandra Gómez-López @uclmedsci.bsky.social, with @cambridgeuni.bsky.social & @sangerinstitute.bsky.social
www.ucl.ac.uk/news/2025/ma...
www.ucl.ac.uk/news/2025/ma...
Origins of common lung cancer that affects smokers discovered
The ‘cell of origin’ of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered, in a new study in mice and humans from researchers at UCL, the Wellcom...
www.ucl.ac.uk
May 2, 2025 at 8:14 AM
The ‘cell of origin’ of the second most common lung cancer and how it becomes dominant in the lung have been discovered, in a new study led by Prof Sam Janes & Dr Sandra Gómez-López @uclmedsci.bsky.social, with @cambridgeuni.bsky.social & @sangerinstitute.bsky.social
www.ucl.ac.uk/news/2025/ma...
www.ucl.ac.uk/news/2025/ma...
Our work describing the biological mechanisms driving the formation of a cancerized field in the airways is now out @science.org!
Huge team effort from @lungs4living.bsky.social and amazing collaborators to delineate the origin of precancerous lung disease 🫁
www.science.org/doi/full/10....
Huge team effort from @lungs4living.bsky.social and amazing collaborators to delineate the origin of precancerous lung disease 🫁
www.science.org/doi/full/10....
www.science.org
May 2, 2025 at 12:14 PM
Our work describing the biological mechanisms driving the formation of a cancerized field in the airways is now out @science.org!
Huge team effort from @lungs4living.bsky.social and amazing collaborators to delineate the origin of precancerous lung disease 🫁
www.science.org/doi/full/10....
Huge team effort from @lungs4living.bsky.social and amazing collaborators to delineate the origin of precancerous lung disease 🫁
www.science.org/doi/full/10....