sandipbasak.bsky.social
@sandipbasak.bsky.social
Excellent work. Congratulations!
November 7, 2025 at 7:43 AM
Special thanks to @sjorsscheres.bsky.social for developing #RELION, the powerful open-source software that made this analysis possible. If anyone has questions or would like guidance on using the scripts, please feel free to reach out!
October 24, 2025 at 5:32 AM
Impressively, we were able to reconstruct nearly all asymmetric conformations previously proposed by @mishakudryashev.bsky.social. Below image shows the final outcome. Thanks @mishakudryashev.bsky.social for depositing the data.
October 24, 2025 at 5:32 AM
This robust approach can be applied to process #cryoEM datasets of cyclic, pseudo-symmetric macromolecules. We’ve made our processing strategy available as user-friendly scripts on GitHub (tinyurl.com/3jenfw6j) and will soon upload a detailed tutorial using deposited 5-HT3AR dataset (EMPIAR-10381).
GitHub - SandipLab/asymReconstruct: Repository for code associated with the manuscript "Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM"
Repository for code associated with the manuscript "Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM" - SandipLab/asymReconstruct
tinyurl.com
October 24, 2025 at 5:32 AM
A big congratulations to our amazing team members
for their outstanding efforts, and thanks to our excellent collaborators @philbiggin.bsky.social and Giriraj Sahu, without whom this work would not have been possible.
October 24, 2025 at 5:32 AM
Congratulations!
October 5, 2025 at 2:27 PM
Congratulations!
June 9, 2025 at 2:04 PM