@sandipbasak.bsky.social
Excellent work. Congratulations!
November 7, 2025 at 7:43 AM
Excellent work. Congratulations!
Special thanks to @sjorsscheres.bsky.social for developing #RELION, the powerful open-source software that made this analysis possible. If anyone has questions or would like guidance on using the scripts, please feel free to reach out!
October 24, 2025 at 5:32 AM
Special thanks to @sjorsscheres.bsky.social for developing #RELION, the powerful open-source software that made this analysis possible. If anyone has questions or would like guidance on using the scripts, please feel free to reach out!
Impressively, we were able to reconstruct nearly all asymmetric conformations previously proposed by @mishakudryashev.bsky.social. Below image shows the final outcome. Thanks @mishakudryashev.bsky.social for depositing the data.
October 24, 2025 at 5:32 AM
Impressively, we were able to reconstruct nearly all asymmetric conformations previously proposed by @mishakudryashev.bsky.social. Below image shows the final outcome. Thanks @mishakudryashev.bsky.social for depositing the data.
This robust approach can be applied to process #cryoEM datasets of cyclic, pseudo-symmetric macromolecules. We’ve made our processing strategy available as user-friendly scripts on GitHub (tinyurl.com/3jenfw6j) and will soon upload a detailed tutorial using deposited 5-HT3AR dataset (EMPIAR-10381).
GitHub - SandipLab/asymReconstruct: Repository for code associated with the manuscript "Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM"
Repository for code associated with the manuscript "Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM" - SandipLab/asymReconstruct
tinyurl.com
October 24, 2025 at 5:32 AM
This robust approach can be applied to process #cryoEM datasets of cyclic, pseudo-symmetric macromolecules. We’ve made our processing strategy available as user-friendly scripts on GitHub (tinyurl.com/3jenfw6j) and will soon upload a detailed tutorial using deposited 5-HT3AR dataset (EMPIAR-10381).
A big congratulations to our amazing team members
for their outstanding efforts, and thanks to our excellent collaborators @philbiggin.bsky.social and Giriraj Sahu, without whom this work would not have been possible.
for their outstanding efforts, and thanks to our excellent collaborators @philbiggin.bsky.social and Giriraj Sahu, without whom this work would not have been possible.
October 24, 2025 at 5:32 AM
A big congratulations to our amazing team members
for their outstanding efforts, and thanks to our excellent collaborators @philbiggin.bsky.social and Giriraj Sahu, without whom this work would not have been possible.
for their outstanding efforts, and thanks to our excellent collaborators @philbiggin.bsky.social and Giriraj Sahu, without whom this work would not have been possible.
Congratulations!
October 5, 2025 at 2:27 PM
Congratulations!
Congratulations!
June 9, 2025 at 2:04 PM
Congratulations!