Sam Connell
@samuelconnell.3i.social
Scientist and Global Sales Director at 3i (@the.3i.social), foodie, family man. Tai Chi and meditation matter. Compassion Heals. Microscopes Rock. https://www.intelligent-imaging.com
Reposted by Sam Connell
“Housing shortage – Jews to blame," letter sticker, German Reich, 1938
zwangsraeume.berlin/en/context
zwangsraeume.berlin/en/context
November 14, 2025 at 2:16 AM
“Housing shortage – Jews to blame," letter sticker, German Reich, 1938
zwangsraeume.berlin/en/context
zwangsraeume.berlin/en/context
Reposted by Sam Connell
Post a bird to support @sbworkersunited.org and warn your followers not to buy Starbucks for the duration of the strike.
November 14, 2025 at 5:18 AM
Post a bird to support @sbworkersunited.org and warn your followers not to buy Starbucks for the duration of the strike.
Post a bird to support @sbworkersunited.org and warn your followers not to buy Starbucks for the duration of the strike.
Searched "bird" in Photos & this seagull from Brannan Street Park in San Francisco asked to come and help out. He's been quietly chilling waiting to get to work for a decade.
Searched "bird" in Photos & this seagull from Brannan Street Park in San Francisco asked to come and help out. He's been quietly chilling waiting to get to work for a decade.
November 14, 2025 at 5:32 AM
Post a bird to support @sbworkersunited.org and warn your followers not to buy Starbucks for the duration of the strike.
Searched "bird" in Photos & this seagull from Brannan Street Park in San Francisco asked to come and help out. He's been quietly chilling waiting to get to work for a decade.
Searched "bird" in Photos & this seagull from Brannan Street Park in San Francisco asked to come and help out. He's been quietly chilling waiting to get to work for a decade.
Reposted by Sam Connell
Cool application of photo click chemistry!
New preprint 🥳! We made photoclickable HaloTag ligands to precisely control protein labeling on living cells. With it, we can do some cool multicolor stuff. Huge congrats to Franzi and all co-authors! Check it out 👇
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 13, 2025 at 5:15 PM
Cool application of photo click chemistry!
Reposted by Sam Connell
New preprint 🥳! We made photoclickable HaloTag ligands to precisely control protein labeling on living cells. With it, we can do some cool multicolor stuff. Huge congrats to Franzi and all co-authors! Check it out 👇
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 13, 2025 at 4:20 PM
New preprint 🥳! We made photoclickable HaloTag ligands to precisely control protein labeling on living cells. With it, we can do some cool multicolor stuff. Huge congrats to Franzi and all co-authors! Check it out 👇
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Sam Connell
Can confirm. I am okay and more motivated than ever to speak up.
Nothing scares this administration more. Their power lies in our silence.
Nothing scares this administration more. Their power lies in our silence.
NIH program officer @jenna-m-norton.bsky.social has been placed on admin leave, sources say.
Norton has been outspoken about the Trump administration's dismantling of science, and she signed the Bethesda Declaration.
Bhattacharya has said that "science is dead without free speech".
Norton has been outspoken about the Trump administration's dismantling of science, and she signed the Bethesda Declaration.
Bhattacharya has said that "science is dead without free speech".
November 14, 2025 at 2:37 AM
Can confirm. I am okay and more motivated than ever to speak up.
Nothing scares this administration more. Their power lies in our silence.
Nothing scares this administration more. Their power lies in our silence.
Reposted by Sam Connell
A bad thing is unfolding at NIH this week: It looks like the Trump administration is trying to replace key civil servant scientific leaders, the Institute Directors, with political hires. These directors control the NIH budget, tens of billions.
A bit of a video explainer here: 1/ 🧪
A bit of a video explainer here: 1/ 🧪
November 13, 2025 at 10:31 PM
A bad thing is unfolding at NIH this week: It looks like the Trump administration is trying to replace key civil servant scientific leaders, the Institute Directors, with political hires. These directors control the NIH budget, tens of billions.
A bit of a video explainer here: 1/ 🧪
A bit of a video explainer here: 1/ 🧪
Reposted by Sam Connell
I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...
November 13, 2025 at 8:49 PM
I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...
Reposted by Sam Connell
Congrats, Momoko @prunus-persica123.bsky.social and all! Excited to see how our former postdoc's work unfolded the mutual inhibitory mechanism bet/w EPFL2 peptide hormone & auxin underpins the intervals of auxin maxima 🌿🔬🥳
Just published @natcomms.nature.com
www.nature.com/articles/s41...
Just published @natcomms.nature.com
www.nature.com/articles/s41...
November 13, 2025 at 8:51 PM
Congrats, Momoko @prunus-persica123.bsky.social and all! Excited to see how our former postdoc's work unfolded the mutual inhibitory mechanism bet/w EPFL2 peptide hormone & auxin underpins the intervals of auxin maxima 🌿🔬🥳
Just published @natcomms.nature.com
www.nature.com/articles/s41...
Just published @natcomms.nature.com
www.nature.com/articles/s41...
Reposted by Sam Connell
Prices aren't coming down. Trump lied. They started going up as soon as he took the wheel.
November 13, 2025 at 4:00 PM
Prices aren't coming down. Trump lied. They started going up as soon as he took the wheel.
Reposted by Sam Connell
Reposted by Sam Connell
You can disagree and argue as much as you like but the point of evaluating something scientifically is that not every statement should be given equal credence because evidence matters
JD Vance: "Science as practiced in its best form is that if you disagree with it, then you ought to criticize it and you ought to argue against it."
November 13, 2025 at 7:36 PM
You can disagree and argue as much as you like but the point of evaluating something scientifically is that not every statement should be given equal credence because evidence matters
Reposted by Sam Connell
We are grieving our friend and brilliant colleague Natalia Duque-Wilckens. A creative scientist, artist, caring mentor, and force for change. Words can’t describe the impact she had on lives at UC Davis, MSU, NC State and beyond. I feel lucky to have known her and wish her time didn’t end so soon
November 13, 2025 at 6:58 PM
We are grieving our friend and brilliant colleague Natalia Duque-Wilckens. A creative scientist, artist, caring mentor, and force for change. Words can’t describe the impact she had on lives at UC Davis, MSU, NC State and beyond. I feel lucky to have known her and wish her time didn’t end so soon
Reposted by Sam Connell
how stupid is it the “glass ceiling” probably just turned out to be “donors want dudes they can blackmail, not competent people who are good at their jobs”
November 13, 2025 at 7:40 PM
how stupid is it the “glass ceiling” probably just turned out to be “donors want dudes they can blackmail, not competent people who are good at their jobs”
Reposted by Sam Connell
After 10 years, I am stepping down as chair of our department and we have an active search going on! Utah is a phenomenal place to live and work and it's been the honor of a lifetime chairing the department founded by Lou Goodman. #MedSky #Neuroskyence Repost!
jobs.chronicle.com/job/37914733...
jobs.chronicle.com/job/37914733...
Chair of Pharmacology and Toxicology - Salt Lake City, Utah job with The University of Utah | 37914733
The University of Utah seeks a Chair of Pharmacology and Toxicology
jobs.chronicle.com
November 12, 2025 at 4:28 PM
After 10 years, I am stepping down as chair of our department and we have an active search going on! Utah is a phenomenal place to live and work and it's been the honor of a lifetime chairing the department founded by Lou Goodman. #MedSky #Neuroskyence Repost!
jobs.chronicle.com/job/37914733...
jobs.chronicle.com/job/37914733...
Reposted by Sam Connell
The department that didn’t hire me is looking for a new chair…time to exact my revenge! But seriously, it’s a great department, someone actually qualified should apply!
After 10 years, I am stepping down as chair of our department and we have an active search going on! Utah is a phenomenal place to live and work and it's been the honor of a lifetime chairing the department founded by Lou Goodman. #MedSky #Neuroskyence Repost!
jobs.chronicle.com/job/37914733...
jobs.chronicle.com/job/37914733...
Chair of Pharmacology and Toxicology - Salt Lake City, Utah job with The University of Utah | 37914733
The University of Utah seeks a Chair of Pharmacology and Toxicology
jobs.chronicle.com
November 12, 2025 at 4:53 PM
The department that didn’t hire me is looking for a new chair…time to exact my revenge! But seriously, it’s a great department, someone actually qualified should apply!
Reposted by Sam Connell
Here's a big thank you to everyone at NIH who is trying to get everything regarding grants and reviews re-started!!!
November 13, 2025 at 5:58 PM
Here's a big thank you to everyone at NIH who is trying to get everything regarding grants and reviews re-started!!!
Reposted by Sam Connell
Big big thanks
to all the program officers and scientific review officers coming back online and managing to instill positivity and we-can-do-this attitudes in emails out to applicants & reviewers who might have wondered: What will happen to all of this good work?
Answer: let's do this.
to all the program officers and scientific review officers coming back online and managing to instill positivity and we-can-do-this attitudes in emails out to applicants & reviewers who might have wondered: What will happen to all of this good work?
Answer: let's do this.
November 13, 2025 at 6:02 PM
Big big thanks
to all the program officers and scientific review officers coming back online and managing to instill positivity and we-can-do-this attitudes in emails out to applicants & reviewers who might have wondered: What will happen to all of this good work?
Answer: let's do this.
to all the program officers and scientific review officers coming back online and managing to instill positivity and we-can-do-this attitudes in emails out to applicants & reviewers who might have wondered: What will happen to all of this good work?
Answer: let's do this.
What a crazy cool paper! First author @pierreucla.bsky.social with a large crew knocked it out of the park. (GIF below from @the.3i.social LLS) Quantifying cell traction forces at the single-fiber scale in 3D: An approach based on deformable photopolymerized fiber arrays www.pnas.org/doi/10.1073/...
November 13, 2025 at 6:21 PM
What a crazy cool paper! First author @pierreucla.bsky.social with a large crew knocked it out of the park. (GIF below from @the.3i.social LLS) Quantifying cell traction forces at the single-fiber scale in 3D: An approach based on deformable photopolymerized fiber arrays www.pnas.org/doi/10.1073/...
Reposted by Sam Connell
How genetically encoded sensors have lit up neuroscience
www.nature.com/articles/d41...
www.nature.com/articles/d41...
How genetically encoded sensors have lit up neuroscience
Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology — although important caveats remain.
www.nature.com
November 13, 2025 at 3:17 PM
How genetically encoded sensors have lit up neuroscience
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Sam Connell
Adding more signs of how NIH science is/was broken: my lab team could not show up for 3 more accepted talks at scientific conferences, totaling 9 for the year now. If you interview current NIH trainees for grad or med schools please understand that we are giving them the best experience we can.
While the government was shut down, 379 NIH study section meetings (containing 24,380 grant applications) were postponed. NIH is committed to getting these reviewed, but please be patient and understanding with staff, as this is a complex and heavy lift.
November 13, 2025 at 2:10 PM
Adding more signs of how NIH science is/was broken: my lab team could not show up for 3 more accepted talks at scientific conferences, totaling 9 for the year now. If you interview current NIH trainees for grad or med schools please understand that we are giving them the best experience we can.
Reposted by Sam Connell
More new NIH institute and center director positions posted
with a closing date of 11/26/25.
hr.nih.gov/careers/open...
These include the Center for Scientific Review (CSR), National Institute of Nursing Research (NINR), National Institute of Allergy and Infectious Diseases (NIAID), ...
1/3
with a closing date of 11/26/25.
hr.nih.gov/careers/open...
These include the Center for Scientific Review (CSR), National Institute of Nursing Research (NINR), National Institute of Allergy and Infectious Diseases (NIAID), ...
1/3
hr.nih.gov
November 12, 2025 at 4:18 PM
More new NIH institute and center director positions posted
with a closing date of 11/26/25.
hr.nih.gov/careers/open...
These include the Center for Scientific Review (CSR), National Institute of Nursing Research (NINR), National Institute of Allergy and Infectious Diseases (NIAID), ...
1/3
with a closing date of 11/26/25.
hr.nih.gov/careers/open...
These include the Center for Scientific Review (CSR), National Institute of Nursing Research (NINR), National Institute of Allergy and Infectious Diseases (NIAID), ...
1/3
Reposted by Sam Connell
Hot take: Most covers of songs are not good.
Some covers are better than the originals, but this is rare.
What are your fave covers that are better than the originals?
Some covers are better than the originals, but this is rare.
What are your fave covers that are better than the originals?
November 12, 2025 at 4:18 PM
Hot take: Most covers of songs are not good.
Some covers are better than the originals, but this is rare.
What are your fave covers that are better than the originals?
Some covers are better than the originals, but this is rare.
What are your fave covers that are better than the originals?
Reposted by Sam Connell
This sounds reasonable but is 100% wrong. Whether you or agree or disagree with a study is completely immaterial. What matters is whether the study was conducted properly and generates valid results. And it's impolitic to say but it's true: you have to have some level of expertise to judge that.
JD Vance: "Science as practiced in its best form is that if you disagree with it, then you ought to criticize it and you ought to argue against it."
November 12, 2025 at 5:57 PM
This sounds reasonable but is 100% wrong. Whether you or agree or disagree with a study is completely immaterial. What matters is whether the study was conducted properly and generates valid results. And it's impolitic to say but it's true: you have to have some level of expertise to judge that.
Reposted by Sam Connell
I’m delighted to see others delighting in tonight’s sky show
what they’re seeing is excitation (light absorbed by “tuned” kinds of matter) & emission (“excited” matter relaxing by releasing light of a different color)
the advanced research microscopes I use every day work on the same principle
what they’re seeing is excitation (light absorbed by “tuned” kinds of matter) & emission (“excited” matter relaxing by releasing light of a different color)
the advanced research microscopes I use every day work on the same principle
November 12, 2025 at 6:11 AM
I’m delighted to see others delighting in tonight’s sky show
what they’re seeing is excitation (light absorbed by “tuned” kinds of matter) & emission (“excited” matter relaxing by releasing light of a different color)
the advanced research microscopes I use every day work on the same principle
what they’re seeing is excitation (light absorbed by “tuned” kinds of matter) & emission (“excited” matter relaxing by releasing light of a different color)
the advanced research microscopes I use every day work on the same principle