Sam Bloom
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sambloom28.bsky.social
Sam Bloom
@sambloom28.bsky.social
91 followers 240 following 0 posts
Postdoc in the @karlsederlab.bsky.social at The Salk Institute for Biological Studies
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Reposted by Sam Bloom
cisnerosmetztli.bsky.social
🧬Register for the GRS on DNA Damage, Mutation & Cancer🧬
Feb 28–Mar 1 2026, Ventura CA
Accepting abstracts for oral presentations! 
📍 Apply here 👉 grc.org/dna-damage-mutation-and-cancer-grs-conference/2026 (www.grc.org/dna-damage-m...)
#DNADamage #GRC#GRS #CallForAbstracts
2026 DNA Damage, Mutation and Cancer (GRS) Seminar GRC
The 2026 Gordon Research Seminar on DNA Damage, Mutation and Cancer (GRS) will be held in Ventura, California. Apply today to reserve your spot.
grc.org
November 5, 2025 at 9:12 PM
Reposted by Sam Bloom
jstarklab.bsky.social
📢📢Apply now for GRS/GRC on DNA Damage Mutation & Cancer in sunny Ventura CA.
November 5, 2025 at 10:02 PM
Reposted by Sam Bloom
joenassour.bsky.social
Out now in CSH Perspectives in Biology (Telomeres & Telomerase) : “Telomere crisis shapes cancer evolution.” cshperspectives.cshlp.org/content/earl...
August 12, 2025 at 3:37 AM
Reposted by Sam Bloom
genesdev.bsky.social
SYMPOSIUM OUTLOOK: #Telomeres at the nexus of #aging, #tumor suppression, and #inflammation: toward an understanding beyond #senescence
By Samuel Bloom & Jan Karlseder
➡️ https://bit.ly/410dJwg
##cshlsymp25 #DNAdamage #replicativesenescence #DNAreplication #crisis #cancer
August 20, 2025 at 2:31 PM
Reposted by Sam Bloom
karlsederlab.bsky.social
Our lab’s latest “hot take” is out in Genes & Development!
We argue for looking beyond senescence to understand how telomeres connect aging, tumor suppression, and inflammation.
Great job @sambloom28.bsky.social!

👉 DOI: 10.1101/gad.353122.125
genesdev.cshlp.org/content/earl...
Telomeres at the nexus of aging, tumor suppression, and inflammation: toward an understanding beyond senescence
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
August 15, 2025 at 2:55 PM
Reposted by Sam Bloom
joenassour.bsky.social
New preprint out! We propose a “degradative flux” mechanism for tonic STING signaling in ALT+ cells, driven by IRF3-dependent trafficking and clearance of immunogenic extrachromosomal telomeric repeats—a process that could be targeted for cancer immunotherapy
www.biorxiv.org/content/10.1...
www.biorxiv.org
April 22, 2025 at 3:35 PM
Reposted by Sam Bloom
dzyla.bsky.social
I've been developing a semantic search tool that covers not just bioRxiv and medRxiv, but the entire PubMed database. This means you can search across a massive collection of biomedical research using keywords, questions, hypotheses, or even full abstracts. Try it out: mssearch.xyz
Streamlit
mssearch.xyz
February 16, 2025 at 7:02 PM
Reposted by Sam Bloom
karlsederlab.bsky.social
Huge thanks to Hannah Trost, Gabriel Matos Rodriguez, Roger Greenberg, and Hilda Pickett for an amazing Mammalian DNA Repair GRS/GRC in Ventura! Already excited for the next one!
February 7, 2025 at 9:23 PM
Reposted by Sam Bloom
karlsederlab.bsky.social
With our lab’s inaugural Blue Sky post we celebrate our latest publication, a review in Nature Reviews Molecular Cell Biology (@natrevmcb.bsky.social) 🥳
Here, we review our current understanding of telomere biology, discussing differences between human and mouse.
www.nature.com/articles/s41...
Telomere function and regulation from mouse models to human ageing and disease - Nature Reviews Molecular Cell Biology
Telomere dysfunction, usually owing to shortening, activates cellular senescence and can contribute to age-associated diseases and cancer. Mouse models are crucial for telomere research, but human and...
www.nature.com
December 17, 2024 at 10:15 PM