Ryan Hong
@ryanjshong.bsky.social
Bioeng PhD @Caltech | synbio & gene regulation
Reposted by Ryan Hong
Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics
ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...
www.nature.com
November 27, 2024 at 4:13 AM
Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Ryan Hong
Excited to finally share Perceptein, a PERCEPtron made of proTEINs: www.science.org/doi/10.1126/...
A synthetic protein-level neural network in mammalian cells
Artificial neural networks provide a powerful paradigm for nonbiological information processing. To understand whether similar principles could enable computation within living cells, we combined de n...
www.science.org
December 13, 2024 at 1:41 PM
Excited to finally share Perceptein, a PERCEPtron made of proTEINs: www.science.org/doi/10.1126/...