Rudra Channappanavar
@rudrachanna007.bsky.social
Associate Professor, Coronavirus-Pathogenesis-Viral Immunity. College of Veterinary Medicine, Oklahoma State University. Views are my own
Reposted by Rudra Channappanavar
🗨️ Just published in Nature Biotechnology: Our CellWhisperer AI enables chat-based analysis of single-cell sequencing data. You can talk to your cells & figure out the biology without writing any computer code. Paper here: www.nature.com/articles/s41.... Annotated walkthrough in a thread below (1/11)
November 11, 2025 at 12:52 PM
🗨️ Just published in Nature Biotechnology: Our CellWhisperer AI enables chat-based analysis of single-cell sequencing data. You can talk to your cells & figure out the biology without writing any computer code. Paper here: www.nature.com/articles/s41.... Annotated walkthrough in a thread below (1/11)
Reposted by Rudra Channappanavar
Delighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better www.nature.com/articles/s41...
A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics - Nature Microbiology
The authors developed a screen to find compounds that modulate intracellular Staphylococcus aureus metabolism and discovered KL1, which sensitizes persisters to antibiotics by reversing host-induced tolerance.
www.nature.com
October 10, 2025 at 1:24 PM
Delighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better www.nature.com/articles/s41...
Reposted by Rudra Channappanavar
Reposted by Rudra Channappanavar
Lei Yuan, Chen Dong et al. reveal that ciliated cells play an immunoregulatory role in allergic #asthma by constitutively expressing IL-17D, which limits #monocyte recruitment to inflamed lungs rupress.org/jem/article/...
In #Macrophages and #DendriticCells collection 👉 rupress.org/jem/collecti...
In #Macrophages and #DendriticCells collection 👉 rupress.org/jem/collecti...
September 12, 2025 at 10:01 AM
Lei Yuan, Chen Dong et al. reveal that ciliated cells play an immunoregulatory role in allergic #asthma by constitutively expressing IL-17D, which limits #monocyte recruitment to inflamed lungs rupress.org/jem/article/...
In #Macrophages and #DendriticCells collection 👉 rupress.org/jem/collecti...
In #Macrophages and #DendriticCells collection 👉 rupress.org/jem/collecti...
Reposted by Rudra Channappanavar
p.s. here's a brief biography of Jokichi Takamine
www.sciencehistory.org/education/sc...
www.sciencehistory.org/education/sc...
Jokichi Takamine
The Japanese chemist helped isolate the hormone epinephrine and developed new methods of fermentation.
www.sciencehistory.org
May 5, 2025 at 7:11 AM
p.s. here's a brief biography of Jokichi Takamine
www.sciencehistory.org/education/sc...
www.sciencehistory.org/education/sc...
Reposted by Rudra Channappanavar
Multi-layered deep immune profiling, SARS-CoV-2 RNAemia and inflammation in unvaccinated COVID-19 individuals with persistent symptoms
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Multi-layered deep immune profiling, SARS-CoV-2 RNAemia and inflammation in unvaccinated COVID-19 individuals with persistent symptoms - Communications Medicine
Rovito et al. conduct deep immune profiling of hospitalized and unvaccinated individuals with persistent symptoms three months post COVID-19. They explore the role of SARS-CoV-2 RNAemia and peripheral...
www.nature.com
May 5, 2025 at 1:20 PM
Multi-layered deep immune profiling, SARS-CoV-2 RNAemia and inflammation in unvaccinated COVID-19 individuals with persistent symptoms
www.nature.com/articles/s43...
www.nature.com/articles/s43...
A proud mentor moment: Our lab wins all awards in grad student oral presentation category during a local Phi- Zeta Symposium at OSU College of Veterinary Medicine.
Roshan Ghimire- Honorary Mention
Cody Whitley- 1st Place
Debarati Chanda-2nd Place
Rakshya Shrestha- 3rd Place
Roshan Ghimire- Honorary Mention
Cody Whitley- 1st Place
Debarati Chanda-2nd Place
Rakshya Shrestha- 3rd Place
April 4, 2025 at 6:46 AM
A proud mentor moment: Our lab wins all awards in grad student oral presentation category during a local Phi- Zeta Symposium at OSU College of Veterinary Medicine.
Roshan Ghimire- Honorary Mention
Cody Whitley- 1st Place
Debarati Chanda-2nd Place
Rakshya Shrestha- 3rd Place
Roshan Ghimire- Honorary Mention
Cody Whitley- 1st Place
Debarati Chanda-2nd Place
Rakshya Shrestha- 3rd Place
Reposted by Rudra Channappanavar
Bluetorial: Women, courage, and leadership
What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
March 9, 2025 at 4:33 AM
Bluetorial: Women, courage, and leadership
What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.
Reposted by Rudra Channappanavar
A study in Nature Microbiology demonstrates that phenotypic flexibility allows influenza A virus to rapidly respond to environmental pressures in a way that provides dynamic adaptation potential in changing surroundings. 🧪
Influenza A virus rapidly adapts particle shape to environmental pressures - Nature Microbiology
Quantitative flow virometry assay to measure the shape of viral particles under various conditions reveals that influenza virus infections dynamically tune shape distribution of progeny particles depending on viral efficiency.
go.nature.com
February 17, 2025 at 11:26 PM
A study in Nature Microbiology demonstrates that phenotypic flexibility allows influenza A virus to rapidly respond to environmental pressures in a way that provides dynamic adaptation potential in changing surroundings. 🧪
Reposted by Rudra Channappanavar
'Why we have evolved so many cytokines for so few transcriptional regulators is not entirely known, but it suggests that the diversity in cell types that can send a signal and cell types that can receive them is more important than diversity in transcriptional programs.'
Cytokines in cancer
Kureshi and Dougan discuss the roles of cytokines in the tumor microenvironment. Although
there is a sophisticated understanding of cytokine networks, therapeutically targeting
cytokine pathways in ca...
www.cell.com
January 24, 2025 at 11:47 PM
'Why we have evolved so many cytokines for so few transcriptional regulators is not entirely known, but it suggests that the diversity in cell types that can send a signal and cell types that can receive them is more important than diversity in transcriptional programs.'