Rommie Merino-Alado
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rommiemicogia.bsky.social
Rommie Merino-Alado
@rommiemicogia.bsky.social
39 followers 110 following 24 posts
🍄Medical Mycology researcher, attending at the Sección de Micología Médica "Dr. Dante Borelli", Instituto de Medicina Tropical, Universidad Central de Venezuela 🇻🇪
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rommiemicogia.bsky.social
November 23, 2025 at 2:03 AM
rommiemicogia.bsky.social
Biopsy of the patient's lesion
November 3, 2025 at 1:27 AM
rommiemicogia.bsky.social
Paracoccidioides venezuelensis dimorphism
November 3, 2025 at 1:26 AM
Reposted by Rommie Merino-Alado
germhuntermd.bsky.social
Invasive candidiasis in intensive care medicine: shaping the future of diagnosis and therapy

Martin-Loeches et al, Intensive Care Medicine

link.springer.com/article/10.1... #IDSky #TxID #MedMycoSky
Algorithm for the management of suspected IC with septic shock. *For patients with IC who do not present with septic shock, empiric antifungal therapy should be withheld. In these cases, investigations should focus on obtaining blood cultures and, where relevant, site-directed samples. Biomarkers such as serum BDG may support discontinuation when suspicion decreases but should not be used as a trigger to initiate antifungal therapy. BDG (1 → 3)-β-D-glucan; IC Invasive candidiasis; R Resistance Table 5: Key actions in management of persistent candidemia Table 6 Combination strategies for difficult deep-seated refractory infections. Combination therapy is not routine. Reserve it for the specific scenarios above (endocarditis, CNS involvement, ocular disease, renal candidiasis with obstruction, persistent candidemia or very high fungal burden despite source control, suspected/proven resistance, major PK uncertainty or delayed TDM), begin with a pre-defined 48–72 h reassessment, obtain early susceptibility testing, perform TDM for azoles and consider it for echinocandins in complex PK settings, and de-escalate to the narrowest effective monotherapy as soon as feasible. In summary, avoid routine concurrent Amphotericin B–azole combinations for Candida spp. unless there is a compelling salvage reason; prefer alternative pairs (e.g., echinocandin + azole) if combination therapy is needed. If stepping from an azole to Amphotericin B, be aware of potential carry-over effects; if stepping from Amphotericin B to an azole, keep the overlap brief
October 27, 2025 at 7:21 PM
Reposted by Rommie Merino-Alado
germhuntermd.bsky.social
Nasal iodophor to reduce Candidozyma auris nasal carriage in nursing home residents

Intriguing pilot study (n=27) that treated C auris-colonized NH residents with intranasal iodophor bid x 5d. Intervention assoc w decreased C auris burden, some were decolonized

academic.oup.com/ofid/advance...
Figure Panel A shows the iodophor treatment timeline and nasal sampling timepoints. Panel B displays a dot plot of C. auris nasal bioburden at each timepoint and Panel C displays a dot plot of changes in C. auris bioburden for culture-based sampling which occurred on Days 1, 5, and 9. Each dot represents a participant. A box is drawn around the median bioburden or change in bioburden. Nasal bioburden was assessed as follows: 0 = no growth; 1 = few (1-2 isolated colonies); 2 = 1+ (growth in first quadrant only); 3 = 2+ (growth into second quadrant); 4 = 3+ (growth into third quadrant); and 5 = 4+ (growth in all quadrants, high burden).
October 27, 2025 at 7:05 PM
rommiemicogia.bsky.social
It's also responsible for some cases of onichomycosis we've seen in our Laboratory.
mapjournals.bsky.social Maximum Academic Press @mapjournals.bsky.social · Oct 25
#SIF
"Neoscytalidium dimidiatum" is a destructive fungal pathogen threatening crops worldwide, especially dragon fruit. This comprehensive review covers its taxonomy, host range, and management strategies.
Details: https://maxapress.com/article/doi/10.48130/sif-0025-0011
#dragonfruit #pathogen
October 26, 2025 at 7:49 PM
Reposted by Rommie Merino-Alado
piotrgasiorowski.bsky.social
Some fungi from Kicin, Wielkopolska (western Poland): Coprinellus micaceus (EN mica cap, PL czernidłaczek błyszczący) and Clitocybe nebularis (EN cloudy funnel, PL lejkówka szarawa).
#grzyby #fungi #mushrooms #fungifriends #mycology
October 25, 2025 at 8:07 PM
Reposted by Rommie Merino-Alado
phypapers.bsky.social
Coccidioides genomes from low-incidence states reveal complex migration history across the western United States https://pubmed.ncbi.nlm.nih.gov/41134192/
October 26, 2025 at 7:24 AM
Reposted by Rommie Merino-Alado
salmantongarcia.bsky.social
“Beyond the Guidelines: Managing invasive fungal infections in critical illness” 🧫

Revisit to the 2024 ATS recommendations on:
1️⃣ Combination therapy for IPA
2️⃣ Empirical/prophylactic treatment for IC in ICU

👉 www.sciencedirect.com/science/arti...
Managing invasive fungal infections in critical illness: reflections on recent American Thoracic Society recommendations
www.sciencedirect.com
October 17, 2025 at 8:31 AM
Reposted by Rommie Merino-Alado
salmantongarcia.bsky.social
🧫 Persistent candidemia: lessons from a European cohort

In 258 patients from 18 countries, 20% had ≥5 days of (+) cultures → higher mortality (50% vs 32%).

Low EQUAL #Candida Scores predicted persistence

💡 Adherence saves lives

🔗 www.journalofinfection.com/article/S016...
October 17, 2025 at 8:43 AM
rommiemicogia.bsky.social
Same Cryptococcus sp. but two stains: Indian ink and Giemsa stain
October 24, 2025 at 3:19 AM
rommiemicogia.bsky.social
Unresponsive disseminated Cryptococcosis in a feline patient. Brain mass, mediastinal enlarged nodes, 2 days of fluconazole and new cutaneous+occular lesions appeared along with positive LFA. Lung and brain biopsies conclusive for cryptococcoma
October 23, 2025 at 1:10 AM
rommiemicogia.bsky.social
Aspergilosis case due to Aspergillus flavus (or newly named Aspergillus section flavi)
October 16, 2025 at 1:47 AM
Reposted by Rommie Merino-Alado
p7037.bsky.social
Viridans Streptococcal Biofilm Evades Immune Detection and Contributes to Inflammation and Rupture of Atherosclerotic Plaques | Journal of the American Heart Association https://www.ahajournals.org/doi/10.1161/JAHA.125.041521
Text Shot: Bacterial DNA from the oral cavity, respiratory tract, gut, and skin has been detected in atherosclerotic plaques, suggesting a role in chronic inflammation linked to atherosclerosis. Chronic bacterial infections often form biofilms resistant to antibiotics and immune detection, giving rise to a new generation of virulent bacteria in suitable conditions. This study explores the role of the immune system in bacterial‐induced inflammation of atherosclerotic plaques.
September 13, 2025 at 2:44 PM
Reposted by Rommie Merino-Alado
ecdc.europa.eu
#JustPublished!
Drug-resistant fungus #CandidozymaAuris is spreading rapidly in European hospitals. #ECDC calls for urgent action.

📈 Cases are rising, outbreaks are larger, and several countries now report local transmission.

Press release: bit.ly/46uR1iK
#CandidaAuris #HAI #IDsky #EpiSky #AMR
Drug-resistant fungus Candidozyma auris confirmed to spread rapidly in European hospitals: ECDC calls for urgent action
The latest survey from ECDC, the fourth of its kind, confirms that Candidozyma auris (formerly Candida auris) continues to spread quickly across European hospitals.
bit.ly
September 11, 2025 at 9:03 AM
Reposted by Rommie Merino-Alado
jamainternalmed.com
📌 Most viewed this week from JAMA Internal Medicine: Among 450 participants, Azelastine nasal spray was associated with a reduced incidence of lab-confirmed SARS-CoV-2 respiratory infections (2.2% compared to 6.7% with placebo).

ja.ma/4pff24U
A graph titled "Cumulative Incidence of Polymerase Chain Reaction-Confirmed Infection With SARS-CoV-2 Over Time" shows cumulative infection rate over time for Placebo and Azelastine, with Placebo showing a higher infection rate.
September 6, 2025 at 11:00 AM
rommiemicogia.bsky.social
We're working hard to build up a fresh and educational Instagram page for Young ISHAM and all ISHAM community! please follow us and together we'll reach a bigger potential in promotion scientific and mycological knowledge
August 30, 2025 at 1:42 AM
rommiemicogia.bsky.social
A few days ago, we had an amazing case (my 1st chromoblastomicosis case EVER🥹)... So we did all the diagnosis algorithm, and we were really expecting Fonsecaea sp.
But...
August 29, 2025 at 2:03 AM
Reposted by Rommie Merino-Alado
iuidfellowship.bsky.social
ann-clinmicrob.biomedcentral.com/articles/10....
Hidden in plain sight: urinary Cryptococcus neoformans missed by routine diagnostics in a patient with acute leukemia - Annals of Clinical Microbiology and Antimicrobials
Cryptococcuria is a rare manifestation of localized cryptococcal disease. We present a case of Cryptococcus neoformans urinary tract infection in an immunocompromised host missed by routine laboratory...
ann-clinmicrob.biomedcentral.com
August 8, 2025 at 11:36 PM
Reposted by Rommie Merino-Alado
germhuntermd.bsky.social
Evaluating the Use of Lower Dose Flucytosine for the Treatment of Cryptococcal Meningitis: A Clinical Trial

Compared to historical controls w/ standard 100 mg/kg flucytosine dose, a CM regimen w/ low dose (60 mg/kg) flucytosine had inferior CSF fungal clearance

academic.oup.com/cid/advance-...
Visual abstract showing inferior early fungicidal activity (primary endpoint) and csf sterility at 2 weeks (secondary endpoint) in experimental arm, no difference in survival (secondary endpoint)
August 8, 2025 at 12:51 PM
rommiemicogia.bsky.social
phypapers.bsky.social phy_papers @phypapers.bsky.social · Aug 9
Two new species of Phaeoclavulina (Gomphaceae, Gomphales) from North China based on morphological and phylogenetic analysis https://pubmed.ncbi.nlm.nih.gov/40778231/
August 9, 2025 at 3:29 AM
rommiemicogia.bsky.social
Say hello to this little fella Histoplasma sp. culture from a clinical sample (cervical node biopsy) HIV negative patient
August 7, 2025 at 10:20 PM
Reposted by Rommie Merino-Alado
asm.org
Microbiome research is changing how we see ourselves, not as separate from other life forms, but part of a codependent system. Explore how this more-than-human view can help solve today’s biggest challenges in the latest issue of Microcosm: asm.social/2wS
The microbiome can be used to illustrate the more-than-human concept, demonstrating that (a) humans are not isolated but are (b) the products of interactions with microbes.
August 5, 2025 at 2:06 PM
Reposted by Rommie Merino-Alado
ofidjournal.bsky.social
Genomic Dynamics of The Emergent Candida auris: Exploring Climate-Dependent Trends

✅ Just Accepted
#IDSky
Genomic Dynamics of The Emergent Candida auris: Exploring Climate-Dependent Trends
Candidozyma auris (formerly known as Candida auris) (C. auris) is a multidrug-resistant fungal pathogen that has emerged as a significant threat to global health.
doi.org
August 5, 2025 at 9:11 PM
Reposted by Rommie Merino-Alado
phypapers.bsky.social
Genomic epidemiology of Histoplasma in Africa https://pubmed.ncbi.nlm.nih.gov/40762488/
August 6, 2025 at 1:24 AM