Sergio Romero²
romeritos.bsky.social
Sergio Romero²
@romeritos.bsky.social
La loca de las proteínas. Associate Professor at Instituto de Fisiología Celular, UNAM (Mexico City). Researching our protein-based world and pushing the boundaries of sequence space by protein design. Fan of cacti, baseball, raccoons, and bank transfers.
Thrilled to share that my former student, Alex Braun, has been awarded the Rainer Rudolph Prize 2024 for his master's thesis on designing artificial enzymes with language models! Immensely proud of him. A toast all the way from Mexico! 🎉👏🌟

Preprint: www.biorxiv.org/content/10.1...
March 19, 2025 at 6:54 PM
How does collagen fold? Very carefully! (And with some help from electrostatics.) Our latest collaborative study uncovers kinetic mechanisms where interchain electrostatic interactions act as molecular clamps to promote proper folding. Check it out! 🎉🌟🧬🧫

www.nature.com/articles/s41...
Deciphering the folding code of collagens - Nature Communications
Collagen triple helices are found in all the three domains of life as well as viruses. Here, the authors show that collagens have converged on a similar folding mechanism that employs salt bridge...
www.nature.com
March 19, 2025 at 4:44 PM
Reposted by Sergio Romero²
Archea and bacteria have collagen-like proteins? I didn't know that! 🤯
Congrats @romeritos.bsky.social and everyone involved in this work!

Deciphering the folding code of collagens
rdcu.be/eed6e
Deciphering the folding code of collagens
Nature Communications - Collagen triple helices are found in all the three domains of life as well as viruses. Here, the authors show that collagens have converged on a similar folding mechanism...
rdcu.be
March 19, 2025 at 4:01 PM
Reposted by Sergio Romero²
The first original research paper from my lab is now out in @biorxivpreprint.bsky.social! www.biorxiv.org/content/10.1...
Tracheal development is an amazing model to study morphogenesis. There are great works out there that show how this tissue elongates, interconnects, and forms branches (1/n)
Adhesion to a common ECM mediates interdependence in tissue morphogenesis in Drosophila
For organs to be functional, the cells and tissues that constitute them must effectively interact with each other and coordinate their behaviours. Halfway during Drosophila embryogenesis, two lateral ...
www.biorxiv.org
March 17, 2025 at 5:21 PM