Roberto Gordillo
@robgordill.bsky.social
Pediatric nephrology
Seattle Children's Hospital
University of Washington
Seattle Children's Hospital
University of Washington
Reposted by Roberto Gordillo
A previously healthy man presented with a 10-day history of blood dripping from one nostril. Twenty days earlier, he had washed his face with mountain spring water. A leech was found on nasal endoscopy (shown in a video). Read the full case details: nej.md/3J6IZUD
#MedSky #Otolaryngology
#MedSky #Otolaryngology
November 3, 2025 at 8:16 PM
A previously healthy man presented with a 10-day history of blood dripping from one nostril. Twenty days earlier, he had washed his face with mountain spring water. A leech was found on nasal endoscopy (shown in a video). Read the full case details: nej.md/3J6IZUD
#MedSky #Otolaryngology
#MedSky #Otolaryngology
Reposted by Roberto Gordillo
Dr. Asaf Bitton, a primary care physician and professor, talks about valuing the critical role of primary care docs.
Hear more in the first episode of Not Otherwise Specified season 3, hosted by NEJM National Correspondent Dr. Lisa Rosenbaum: nej.md/3W416gK
#MedSky
Hear more in the first episode of Not Otherwise Specified season 3, hosted by NEJM National Correspondent Dr. Lisa Rosenbaum: nej.md/3W416gK
#MedSky
October 19, 2025 at 7:04 PM
Dr. Asaf Bitton, a primary care physician and professor, talks about valuing the critical role of primary care docs.
Hear more in the first episode of Not Otherwise Specified season 3, hosted by NEJM National Correspondent Dr. Lisa Rosenbaum: nej.md/3W416gK
#MedSky
Hear more in the first episode of Not Otherwise Specified season 3, hosted by NEJM National Correspondent Dr. Lisa Rosenbaum: nej.md/3W416gK
#MedSky
Reposted by Roberto Gordillo
lol, people measuring BP incorrectly since, (at least), 1881, 👀😳🤦🏼♀️😅😂 #hypertension
cc: Dr. @drjmluther.bsky.social - for your photos 🤓😃😂
#NephSky
cc: Dr. @drjmluther.bsky.social - for your photos 🤓😃😂
#NephSky
October 8, 2025 at 1:19 AM
lol, people measuring BP incorrectly since, (at least), 1881, 👀😳🤦🏼♀️😅😂 #hypertension
cc: Dr. @drjmluther.bsky.social - for your photos 🤓😃😂
#NephSky
cc: Dr. @drjmluther.bsky.social - for your photos 🤓😃😂
#NephSky
Reposted by Roberto Gordillo
Climate change represents a threat to kidney health, particularly in pediatrics, where children are more vulnerable to heat injuries & environmental toxins. Read this Review of green nephrology: environmentally sustainable kidney care in pediatrics.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
August 28, 2025 at 7:06 PM
Climate change represents a threat to kidney health, particularly in pediatrics, where children are more vulnerable to heat injuries & environmental toxins. Read this Review of green nephrology: environmentally sustainable kidney care in pediatrics.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Roberto Gordillo
Day 1️⃣ of the SEISMIC C3G and IC-MPGN focused on improving the future for those affected by C3G and IC-MPGN. Highlights include the urgency to accelerate diagnosis and treatment, alongside the significance of biomarkers and centers of excellence. Today's insights were powerful💥.
July 18, 2025 at 7:48 PM
Day 1️⃣ of the SEISMIC C3G and IC-MPGN focused on improving the future for those affected by C3G and IC-MPGN. Highlights include the urgency to accelerate diagnosis and treatment, alongside the significance of biomarkers and centers of excellence. Today's insights were powerful💥.
Reposted by Roberto Gordillo
An analysis confirmed the efficacy and safety of #pegcetacoplan for patients with C3G/IC-MPGN and nephrotic range #proteinuria. #C3G #ICMPGN #kidneydisease #nephrology #nephsky www.docwirenews.com/post/pegceta...
Pegcetacoplan Benefits Patients With C3G/IC-MPGN and Nephrotic Proteinuria | Docwire News
An analysis confirmed the efficacy and safety of pegcetacoplan for patients with C3 glomerulopathy and primary immune complex membranoproliferative and nephrotic range proteinuria.
www.docwirenews.com
July 10, 2025 at 5:04 PM
An analysis confirmed the efficacy and safety of #pegcetacoplan for patients with C3G/IC-MPGN and nephrotic range #proteinuria. #C3G #ICMPGN #kidneydisease #nephrology #nephsky www.docwirenews.com/post/pegceta...
Reposted by Roberto Gordillo
A multicenter prospective cohort study evaluating impact of an active delisting strategy to enable kidney transplantation in wait-listed candidates with calculated Panel Reactive Antibody ≥ 99.9%
doi.org/10.1016/j.kint.2025.04.031
#NephSky #MedSky #kidneytransplantation
doi.org/10.1016/j.kint.2025.04.031
#NephSky #MedSky #kidneytransplantation
June 9, 2025 at 11:42 AM
A multicenter prospective cohort study evaluating impact of an active delisting strategy to enable kidney transplantation in wait-listed candidates with calculated Panel Reactive Antibody ≥ 99.9%
doi.org/10.1016/j.kint.2025.04.031
#NephSky #MedSky #kidneytransplantation
doi.org/10.1016/j.kint.2025.04.031
#NephSky #MedSky #kidneytransplantation
Reposted by Roberto Gordillo
El ensayo STAMP comparó ambos tratamientos en niños con recaídas frecuentes o corticodependencia.
¿Cuál fue más eficaz? ¿Qué tan seguros son? #NephJC
VA by @dramiliflores.bsky.social
www.nephjc.com/news/2025/6/8/tac-o-mmf-en-el-sd-nefrotico-pediatrico
¿Cuál fue más eficaz? ¿Qué tan seguros son? #NephJC
VA by @dramiliflores.bsky.social
www.nephjc.com/news/2025/6/8/tac-o-mmf-en-el-sd-nefrotico-pediatrico
¿TAC o MMF en el síndrome nefrótico pediátrico? — NephJC
El ensayo STAMP comparó ambos tratamientos en niños con recaídas frecuentes o corticodependencia. ¿Cuál fue más eficaz? ¿Qué tan seguros son? 🖼️ Revisa el VA completo #NephJC
www.nephjc.com
June 9, 2025 at 11:50 AM
El ensayo STAMP comparó ambos tratamientos en niños con recaídas frecuentes o corticodependencia.
¿Cuál fue más eficaz? ¿Qué tan seguros son? #NephJC
VA by @dramiliflores.bsky.social
www.nephjc.com/news/2025/6/8/tac-o-mmf-en-el-sd-nefrotico-pediatrico
¿Cuál fue más eficaz? ¿Qué tan seguros son? #NephJC
VA by @dramiliflores.bsky.social
www.nephjc.com/news/2025/6/8/tac-o-mmf-en-el-sd-nefrotico-pediatrico
Reposted by Roberto Gordillo
Evaluation of Methodologies in Anti-nephrin Autoantibody Detection
doi.org/10.1016/j.kint.2025.05.018
#OpenAccess #MedSky #NephSky #fsgs #focalsegmentalglomerulosclerosis #minimalchangedisease
doi.org/10.1016/j.kint.2025.05.018
#OpenAccess #MedSky #NephSky #fsgs #focalsegmentalglomerulosclerosis #minimalchangedisease
June 9, 2025 at 12:24 PM
Evaluation of Methodologies in Anti-nephrin Autoantibody Detection
doi.org/10.1016/j.kint.2025.05.018
#OpenAccess #MedSky #NephSky #fsgs #focalsegmentalglomerulosclerosis #minimalchangedisease
doi.org/10.1016/j.kint.2025.05.018
#OpenAccess #MedSky #NephSky #fsgs #focalsegmentalglomerulosclerosis #minimalchangedisease
Reposted by Roberto Gordillo
Uncontrolled diabetes mellitus (DM) accelerates atherosclerosis & vascular diseases. Read this Original Article on serum sclerostin as a marker of micro- & macrovascular complications among children & adolescents w/type 1 DM. Open Access.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
May 14, 2025 at 6:34 PM
Uncontrolled diabetes mellitus (DM) accelerates atherosclerosis & vascular diseases. Read this Original Article on serum sclerostin as a marker of micro- & macrovascular complications among children & adolescents w/type 1 DM. Open Access.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Roberto Gordillo
Sparsentan is now approved for the treatment of IgAN in European Union countries. #igan #iganephropathy #kidneydisease #nephrology #nephsky www.docwirenews.com/post/eu-appr...
EU Approves Sparsentan for Treatment of IgAN | Docwire News
The European Commission has granted standard approval to sparsentan for the treatment of adults with primary IgA nephropathy (IgAN).
www.docwirenews.com
May 8, 2025 at 8:50 PM
Sparsentan is now approved for the treatment of IgAN in European Union countries. #igan #iganephropathy #kidneydisease #nephrology #nephsky www.docwirenews.com/post/eu-appr...
Reposted by Roberto Gordillo
AKI commonly occurs in critically ill children, but its impact on pediatric growth outcomes has been sparsely described. Read this Systematic Review /Meta-analysis comparing growth in children w/a history of AKI to those w/o AKI. Open Access
link.springer.com/article/10.1...
link.springer.com/article/10.1...
May 9, 2025 at 5:36 PM
AKI commonly occurs in critically ill children, but its impact on pediatric growth outcomes has been sparsely described. Read this Systematic Review /Meta-analysis comparing growth in children w/a history of AKI to those w/o AKI. Open Access
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Roberto Gordillo
Fibroblast growth factor (FGF) 23 and FGF receptor 4 induced cardiac mitochondrial dysfunction as a new target in #CKD?
doi.org/10.1016/j.kint.2025.02.017
Original article: doi.org/10.1016/j.kint.2025.01.024
#KICommentary #MedSky #NephSky #chronickidneydisease
doi.org/10.1016/j.kint.2025.02.017
Original article: doi.org/10.1016/j.kint.2025.01.024
#KICommentary #MedSky #NephSky #chronickidneydisease
May 6, 2025 at 2:05 PM
Fibroblast growth factor (FGF) 23 and FGF receptor 4 induced cardiac mitochondrial dysfunction as a new target in #CKD?
doi.org/10.1016/j.kint.2025.02.017
Original article: doi.org/10.1016/j.kint.2025.01.024
#KICommentary #MedSky #NephSky #chronickidneydisease
doi.org/10.1016/j.kint.2025.02.017
Original article: doi.org/10.1016/j.kint.2025.01.024
#KICommentary #MedSky #NephSky #chronickidneydisease
Reposted by Roberto Gordillo
Read these Clinical Insights into a 17-yr-old male who developed AKI w/cast nephropathy following a 6-day high-dose creatine loading regimen. This case highlights the risks of high-dose creatine use.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
May 5, 2025 at 6:49 PM
Read these Clinical Insights into a 17-yr-old male who developed AKI w/cast nephropathy following a 6-day high-dose creatine loading regimen. This case highlights the risks of high-dose creatine use.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Roberto Gordillo
Thrombotic microangiopathy following scorpion envenomation
doi.org/10.1016/j.kint.2024.10.033
#KINephrologyImage #NephSky #MedSky #SkyNeph
doi.org/10.1016/j.kint.2024.10.033
#KINephrologyImage #NephSky #MedSky #SkyNeph
May 1, 2025 at 4:55 PM
Thrombotic microangiopathy following scorpion envenomation
doi.org/10.1016/j.kint.2024.10.033
#KINephrologyImage #NephSky #MedSky #SkyNeph
doi.org/10.1016/j.kint.2024.10.033
#KINephrologyImage #NephSky #MedSky #SkyNeph
Reposted by Roberto Gordillo
Glomerular diseases are a leading cause of CKD worldwide. Read this Review of monogenic podocytopathies & mechanisms by which single-gene defects lead to podocyte injury & glomerulosclerosis. Free access this month.
bit.ly/4cUA5Us
bit.ly/4cUA5Us
May 1, 2025 at 7:38 PM
Glomerular diseases are a leading cause of CKD worldwide. Read this Review of monogenic podocytopathies & mechanisms by which single-gene defects lead to podocyte injury & glomerulosclerosis. Free access this month.
bit.ly/4cUA5Us
bit.ly/4cUA5Us
Reposted by Roberto Gordillo
The erythropoietin resistance index (ERI) is an indicator of erythropoietin (EPO) resistance & is related to a worse prognosis in patients on hemodialysis (HD). Read this Original Article on EPO resistance in children w/kidney failure on HD. Open Access.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
April 30, 2025 at 5:34 PM
The erythropoietin resistance index (ERI) is an indicator of erythropoietin (EPO) resistance & is related to a worse prognosis in patients on hemodialysis (HD). Read this Original Article on EPO resistance in children w/kidney failure on HD. Open Access.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Roberto Gordillo
Nocturnal enuresis (NE) is a socially stigmatizing & stressful childhood condition. Read this Systematic Review/ Meta-Analysis assessing the efficacy of multiple drugs in pediatric NE through a network meta-analysis (NMA).
link.springer.com/article/10.1...
link.springer.com/article/10.1...
April 29, 2025 at 4:11 PM
Nocturnal enuresis (NE) is a socially stigmatizing & stressful childhood condition. Read this Systematic Review/ Meta-Analysis assessing the efficacy of multiple drugs in pediatric NE through a network meta-analysis (NMA).
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Roberto Gordillo
DSA testing isn’t the whole story.
Routine assays detect HLA class I & II antibodies — but miss others.
🔍 AMR can involve non-HLA targets:
AT1R, ETAR, MICA, Collagen I/V, K-α tubulin, and more.
Result? “False negative” DSA in patients with real immune injury. #NephJC
pmc.ncbi.nlm.nih.gov...
Routine assays detect HLA class I & II antibodies — but miss others.
🔍 AMR can involve non-HLA targets:
AT1R, ETAR, MICA, Collagen I/V, K-α tubulin, and more.
Result? “False negative” DSA in patients with real immune injury. #NephJC
pmc.ncbi.nlm.nih.gov...
Non-HLA Antibodies in Kidney Transplantation: Immunity and Genetic Insights - PMC
The polymorphic human leukocyte antigen (HLA) system has been considered the main target for alloimmunity, but the non-HLA antibodies and autoimmunity have gained importance in kidney transplantation (KT). Apart from the endothelial injury, ...
pmc.ncbi.nlm.nih.gov
April 30, 2025 at 1:13 AM
DSA testing isn’t the whole story.
Routine assays detect HLA class I & II antibodies — but miss others.
🔍 AMR can involve non-HLA targets:
AT1R, ETAR, MICA, Collagen I/V, K-α tubulin, and more.
Result? “False negative” DSA in patients with real immune injury. #NephJC
pmc.ncbi.nlm.nih.gov...
Routine assays detect HLA class I & II antibodies — but miss others.
🔍 AMR can involve non-HLA targets:
AT1R, ETAR, MICA, Collagen I/V, K-α tubulin, and more.
Result? “False negative” DSA in patients with real immune injury. #NephJC
pmc.ncbi.nlm.nih.gov...
Reposted by Roberto Gordillo
Analysis of the prespecified FIDELITY pooled patient dataset examined the efficacy and safety of #finerenone in patients with an acute change in #estimatedglomerularfiltrationrate
doi.org/10.1016/j.kint.2025.03.018
#OpenAccess #MedSky #NephSky #kidney #eGFR
doi.org/10.1016/j.kint.2025.03.018
#OpenAccess #MedSky #NephSky #kidney #eGFR
April 24, 2025 at 3:25 PM
Analysis of the prespecified FIDELITY pooled patient dataset examined the efficacy and safety of #finerenone in patients with an acute change in #estimatedglomerularfiltrationrate
doi.org/10.1016/j.kint.2025.03.018
#OpenAccess #MedSky #NephSky #kidney #eGFR
doi.org/10.1016/j.kint.2025.03.018
#OpenAccess #MedSky #NephSky #kidney #eGFR
Reposted by Roberto Gordillo
Accurate assessment of kidney function is essential in treating pediatric patients dosed w/nephrotoxic chemotherapy. Read this Original Article comparing GFR estimation equations using creatinine, cystatin C, & their combination in pediatric hematology–oncology.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
April 24, 2025 at 3:35 PM
Accurate assessment of kidney function is essential in treating pediatric patients dosed w/nephrotoxic chemotherapy. Read this Original Article comparing GFR estimation equations using creatinine, cystatin C, & their combination in pediatric hematology–oncology.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Roberto Gordillo
Glucocorticoid Exposure and Infection in Children and Adults With Glomerular Disease: Findings From the Cure Glomerulonephropathy Study
bit.ly/3DHbXai (FREE)
bit.ly/3DHbXai (FREE)
April 23, 2025 at 10:02 AM
Glucocorticoid Exposure and Infection in Children and Adults With Glomerular Disease: Findings From the Cure Glomerulonephropathy Study
bit.ly/3DHbXai (FREE)
bit.ly/3DHbXai (FREE)
Reposted by Roberto Gordillo
Alport Syndrome (AS) is a genetic disorder affecting type IV collagen, leading to hearing loss, eye problems & progressive CKD. Read this Research Letter on results of a European Society of Paediatric Nephrology survey to assess awareness of guidance for AS.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
April 23, 2025 at 5:17 PM
Alport Syndrome (AS) is a genetic disorder affecting type IV collagen, leading to hearing loss, eye problems & progressive CKD. Read this Research Letter on results of a European Society of Paediatric Nephrology survey to assess awareness of guidance for AS.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Roberto Gordillo
Several case reports describe new onset or relapsed NS after COVID-19 mRNA vaccination, but there have been no systematic studies in children. Read this Original Article on the association of COVID-19 vaccination w/relapsed NS & new onset NS in children.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
April 23, 2025 at 5:36 PM
Several case reports describe new onset or relapsed NS after COVID-19 mRNA vaccination, but there have been no systematic studies in children. Read this Original Article on the association of COVID-19 vaccination w/relapsed NS & new onset NS in children.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Roberto Gordillo
Kidney disease should be recognised on WHO's priority list of non-communicable diseases, alongside cancer, cardiovascular disease, and diabetes
https://go.nature.com/4lLJ5iY
https://go.nature.com/4lLJ5iY
Kidney disease is a worldwide killer. Treat it that way
The international community has a golden opportunity to start reining in the escalating, mostly ignored global burden of chronic kidney disease.
go.nature.com
April 22, 2025 at 4:26 PM
Kidney disease should be recognised on WHO's priority list of non-communicable diseases, alongside cancer, cardiovascular disease, and diabetes
https://go.nature.com/4lLJ5iY
https://go.nature.com/4lLJ5iY