Rija Zaidi
rijazaidi.bsky.social
Rija Zaidi
@rijazaidi.bsky.social
PhD Student | Computational Cancer Genomics Lab | UCL Cancer Institute

W: https://sites.google.com/view/ccgresearchgroup/meet-the-team/rija-zaidi
LinkedIn: https://uk.linkedin.com/in/rija-zaidi-a5220a227
How much do algorithmic and experimental choices drive the accuracy of reconstructing tumour evolution?

In this Cancer Research commentary, @zaccasimo.bsky.social and I discuss a recent Nature Biotech benchmarking paper exploring this question:

bit.ly/3VAMRQs
Tumor Evolution Reconstruction Is Heavily Influenced by Algorithmic and Experimental Choices
Tumor progression is an evolutionary process during which cells acquire distinct genetic alterations. Several cancer evolutionary studies reconstruct this evolutionary process by applying bulk DNA seq...
bit.ly
December 16, 2024 at 11:56 AM
Reposted by Rija Zaidi
🚨So proud to present the first study from our @ccg-ucl.bsky.social group together with @charlesswanton.bsky.social @NnennayaKanu and led by @ojlucas.bsky.social with key collaboration @sophie-ward.bsky.social and fundamental support @rijazaidi.bsky.social @abibunkum.bsky.social & others

Out now👇
🧵👇
Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER - Nature Genetics
Single-cell Proliferation Rate Inference in Non-homogeneous Tumors through Evolutionary Routes (SPRINTER) allows users to infer proliferation rates of individual clones within a tumor from single-cell...
doi.org
November 29, 2024 at 1:25 PM