Reika Tei
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reikatei.bsky.social
Reika Tei
@reikatei.bsky.social
LSRF postdoc in Alice Ting Lab at Stanford | Protein engineering, cell signaling, chemical biology, lipids | PhD in Jeremy Baskin Lab at Cornell Chemistry
My personal #lipidtime highlight is antigen-gated control of Gq/DAG signaling!🚦 Using PAGER-Gq, we showed DAG production driven by soluble and surface antigens in HEK cells and neurons. Plus, neuron images reveal local DAG production at antigen-contact membranes! Can it be something useful?🤔
December 4, 2024 at 8:06 PM
Our paper about the development of programmable antigen-gated G-protein-coupled engineered receptors (PAGERs) is published today! www.nature.com/articles/s41...
PAGERs couple detection of a wide range of custom-defined antigen to a variety of output including transgene expression and cell signaling.
December 4, 2024 at 6:32 PM