Quentin Leclerc
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quentinlclrc.bsky.social
Quentin Leclerc
@quentinlclrc.bsky.social
Assistant Professor in public health | Infectious disease dynamics, health risks assessment & AMR | Conservatoire National des Arts et Métiers & Institut Pasteur 🖥️ 🦠
And finally Chloé Aupépin presented a poster on the impact of bacterial vaccines on #AMR ! 🦠

Using modelling, we can identify which bacteria and vaccine characteristics influence most the impact of these vaccines on reducing infections 📉
November 14, 2025 at 3:49 PM
Another day another presentation, this time by Elise Hodbert on patient-transfer networks within and between hospitals! 🏥

Networks are mostly used for surveillance, to identify the facilities to monitor to detect outbreaks early. Possibly under-used for infectious disease transmission modelling...?
November 14, 2025 at 10:55 AM
Overall, we identified optimal conditions to maximize quarantine hospital strategy benefits in an epidemic situation. We propose several recommendations to implement such a strategy when facing a virus with characteristics similar than SARS-CoV-2.

Thanks again to all co-authors for this work! 😁
7/7
October 17, 2025 at 9:07 AM
Of course, deciding whether or not to implement this strategy depends on other factors.
However, importantly, other studies did not find a difference in the mental health of HCWs between quarantine and non-quarantine hospitals, suggesting this would not be a barrier to implementation.

6/7
Mental health status of health-care professionals working in quarantine and non-quarantine Egyptian hospitals during the COVID-19 pandemic - PubMed
Female and younger age health care professionals were more prone to report adverse psychological symptoms. More and earlier screening for health-care professionals dealing with COVID-19, in addition t...
pubmed.ncbi.nlm.nih.gov
October 17, 2025 at 9:07 AM
However, we find that this strategy only has a strong impact if:
- epidemic control is high in the community
- symptomatic HCWs comply well with self-isolation
Otherwise, increased transmission in the community counters the benefit of reduced nosocomial risk.

5/7
October 17, 2025 at 9:07 AM
In a medium-sized city with two hospitals, we estimate that converting one of the two hospitals to a "quarantine hospital" can decrease the attack rate in HCWs by more than 10 percentage points, and the attack rate in non-HCWs by more than 20pp.

4/7
October 17, 2025 at 9:07 AM
As shown in other work (eg bmcinfectdis.biomedcentral.com/articles/10....), hospital-acquired infections can significantly drive overall COVID-19 dynamics, hence the importance of reducing them.

In our work, we show that the quarantine hospital strategy can be effective for this purpose.

3/7
The contribution of hospital-acquired infections to the COVID-19 epidemic in England in the first half of 2020 - BMC Infectious Diseases
Background SARS-CoV-2 is known to transmit in hospital settings, but the contribution of infections acquired in hospitals to the epidemic at a national scale is unknown. Methods We used comprehensive ...
bmcinfectdis.biomedcentral.com
October 17, 2025 at 9:07 AM
Quarantine hospitals were fully dedicated to the care of COVID-19 infected patients & staffed by healthcare workers staying continuously inside for 1-2 week-long shifts.
To understand their impact compared to keeping usual hospital organisation, we built a model coupling hospitals & community 💻

2/7
October 17, 2025 at 9:07 AM
And no, I will never stop reminding people that these are burden *estimates* and not data, this is most certainly a hill I will die on 🙃
October 13, 2025 at 7:40 AM
Haha merci, je transmettrai à mon pote caché dans le public qui a joué au photographe pour l'occasion 😂
October 7, 2025 at 12:46 PM
Programme pour moi:
- tous les jours : stand "Révéler les dynamiques invisibles des épidémies"
- vendredi 21h05: "Juste Nombre", tentez votre chance pour gagner des lots !
- vendredi 22h : "Speed Searching", je répondrai à vos questions les plus folles (eg: quelle quantité de café je bois par jour?)
October 2, 2025 at 7:55 AM