Victor Puelles
@puellesv.bsky.social
Reposted by Victor Puelles
Doctoral (PhD) Position – Spatial Transcriptomics, Bioinformatics & Mucosal Immunology
📍 Karolinska Institutet, Sweden
🗓️ Deadline: Dec 10, 2025
kidoktorand.varbi.com/what:job/job...
#SpatialTranscriptomics #Bioinformatics #MucosalImmunology
#SingleCellOmics #IBDResearch
#SystemsImmunology
📍 Karolinska Institutet, Sweden
🗓️ Deadline: Dec 10, 2025
kidoktorand.varbi.com/what:job/job...
#SpatialTranscriptomics #Bioinformatics #MucosalImmunology
#SingleCellOmics #IBDResearch
#SystemsImmunology
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
November 29, 2025 at 4:15 PM
Doctoral (PhD) Position – Spatial Transcriptomics, Bioinformatics & Mucosal Immunology
📍 Karolinska Institutet, Sweden
🗓️ Deadline: Dec 10, 2025
kidoktorand.varbi.com/what:job/job...
#SpatialTranscriptomics #Bioinformatics #MucosalImmunology
#SingleCellOmics #IBDResearch
#SystemsImmunology
📍 Karolinska Institutet, Sweden
🗓️ Deadline: Dec 10, 2025
kidoktorand.varbi.com/what:job/job...
#SpatialTranscriptomics #Bioinformatics #MucosalImmunology
#SingleCellOmics #IBDResearch
#SystemsImmunology
Reposted by Victor Puelles
Truly happy to host Victor Puelles in Marburg today, talking about complex tissue analysis across biological scales. Thrilling science and exciting discussions! @puellesv.bsky.social
November 27, 2025 at 6:39 PM
Truly happy to host Victor Puelles in Marburg today, talking about complex tissue analysis across biological scales. Thrilling science and exciting discussions! @puellesv.bsky.social
Reposted by Victor Puelles
Really excited for our November issue, and I feel like I'm starting to get into the groove of writing editorials for nBME (with the help of the team of course!). Please check it out!
November 17, 2025 at 7:39 PM
Really excited for our November issue, and I feel like I'm starting to get into the groove of writing editorials for nBME (with the help of the team of course!). Please check it out!
Reposted by Victor Puelles
I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...
November 13, 2025 at 8:49 PM
I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...
Reposted by Victor Puelles
BioContextAI is an open-source initiative for creating agentic biomedical research assistants from standardized components go.nature.com/3JmqKux
rdcu.be/ePz3v
rdcu.be/ePz3v
BioContextAI is a community hub for agentic biomedical systems - Nature Biotechnology
Nature Biotechnology - BioContextAI is a community hub for agentic biomedical systems
go.nature.com
November 12, 2025 at 3:04 PM
BioContextAI is an open-source initiative for creating agentic biomedical research assistants from standardized components go.nature.com/3JmqKux
rdcu.be/ePz3v
rdcu.be/ePz3v
Reposted by Victor Puelles
The Eknoyan Lectureship at #KidneyWk will cover KDIGO Guidelines for CKD on Saturday. Read about the speaker in #ASNKidneyNews kidney.pub/KN1710-55
November 6, 2025 at 9:00 PM
The Eknoyan Lectureship at #KidneyWk will cover KDIGO Guidelines for CKD on Saturday. Read about the speaker in #ASNKidneyNews kidney.pub/KN1710-55
Reposted by Victor Puelles
At #KidneyWk? Celebrate and listen to the ASN-American Heart Association Donald W. Seldin Young Investigator Award winner, Rafael Kramann, who will speak on “Cell by Cell, Space by Space: Unraveling Fibrosis in the Kidney and Heart” on Friday, November 7. kidney.pub/KN1710-35 #ASNKidneyNews
November 6, 2025 at 10:00 PM
At #KidneyWk? Celebrate and listen to the ASN-American Heart Association Donald W. Seldin Young Investigator Award winner, Rafael Kramann, who will speak on “Cell by Cell, Space by Space: Unraveling Fibrosis in the Kidney and Heart” on Friday, November 7. kidney.pub/KN1710-35 #ASNKidneyNews
Reposted by Victor Puelles
BioContextAI is a community hub for agentic biomedical systems - @puellesv.bsky.social @biocontext.ai go.nature.com/3JmqKux
BioContextAI is a community hub for agentic biomedical systems - Nature Biotechnology
Nature Biotechnology - BioContextAI is a community hub for agentic biomedical systems
go.nature.com
November 6, 2025 at 6:28 PM
BioContextAI is a community hub for agentic biomedical systems - @puellesv.bsky.social @biocontext.ai go.nature.com/3JmqKux
Reposted by Victor Puelles
🤖🧬 New biomedical MCP server added to the registry:
Skill-To-MCP Server
Check it out at https://biocontext.ai/registry/biocontext-ai/skill-to-mcp
Skill-To-MCP Server
Check it out at https://biocontext.ai/registry/biocontext-ai/skill-to-mcp
October 26, 2025 at 7:55 PM
🤖🧬 New biomedical MCP server added to the registry:
Skill-To-MCP Server
Check it out at https://biocontext.ai/registry/biocontext-ai/skill-to-mcp
Skill-To-MCP Server
Check it out at https://biocontext.ai/registry/biocontext-ai/skill-to-mcp
Reposted by Victor Puelles
Our new review in @natbiomedeng.nature.com is out!
RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits.
free to read 🔗 rdcu.be/eLxGs
RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits.
free to read 🔗 rdcu.be/eLxGs
Targeting and tracking mRNA lipid nanoparticles at the particle, transcript and protein level
Nature Biomedical Engineering - This Review explores strategies for targeting and tracking RNA-LNP drugs, monitoring their in vivo behaviour, enhancing tissue-specific delivery, and using synthetic...
rdcu.be
October 17, 2025 at 5:16 PM
Our new review in @natbiomedeng.nature.com is out!
RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits.
free to read 🔗 rdcu.be/eLxGs
RNA-loaded lipid nanoparticles (LNPs) have huge potential—but their strong liver and immune cell uptake has mostly confined them to vaccines and liver therapies. We explore how to move beyond those limits.
free to read 🔗 rdcu.be/eLxGs
Reposted by Victor Puelles
The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery.
#Microscopy #Lightsheet #syGlass
#Microscopy #Lightsheet #syGlass
October 23, 2025 at 3:33 PM
The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery.
#Microscopy #Lightsheet #syGlass
#Microscopy #Lightsheet #syGlass
Reposted by Victor Puelles
🦠🔬🤖🧑💻 #mAIcrobe is out! With @pinholab.bsky.social's lab, we launched an open-source framework for high-throughput bacterial image analysis. By rockstars A. Brito & B. Saraiva et al, making #DeepLearning for phenotyping accessible! Easy to use, plus model training
📜 www.biorxiv.org/content/10.1...
📜 www.biorxiv.org/content/10.1...
October 22, 2025 at 11:10 AM
🦠🔬🤖🧑💻 #mAIcrobe is out! With @pinholab.bsky.social's lab, we launched an open-source framework for high-throughput bacterial image analysis. By rockstars A. Brito & B. Saraiva et al, making #DeepLearning for phenotyping accessible! Easy to use, plus model training
📜 www.biorxiv.org/content/10.1...
📜 www.biorxiv.org/content/10.1...
Reposted by Victor Puelles
Job opportunity at the University of Zurich! 📢
We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
1/3
We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
1/3
October 10, 2025 at 8:58 AM
Job opportunity at the University of Zurich! 📢
We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
1/3
We are looking for a 𝐋𝐚𝐛𝐨𝐫𝐚𝐭𝐨𝐫𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐢𝐚𝐧 / 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭 (𝟒𝟎%) to join our Microscopy Innovation Platform (MIP), an open-source initiative focused on advancing and making light-sheet and multiphoton microscopy accessible to researchers.
1/3
Reposted by Victor Puelles
✨🥳🎉 Heartfelt congratulations to Humboldtians Susumu Kitagawa and Omar M. Yaghi on winning the #NobelPrize in Chemistry 2025 which they share with Richard Robson for the development of "metal-organic frameworks"!
We are truly honoured to have supported a step in their exceptional journey! 💚
We are truly honoured to have supported a step in their exceptional journey! 💚
October 8, 2025 at 10:50 AM
✨🥳🎉 Heartfelt congratulations to Humboldtians Susumu Kitagawa and Omar M. Yaghi on winning the #NobelPrize in Chemistry 2025 which they share with Richard Robson for the development of "metal-organic frameworks"!
We are truly honoured to have supported a step in their exceptional journey! 💚
We are truly honoured to have supported a step in their exceptional journey! 💚
Reposted by Victor Puelles
✨✨✨ Huge congratulations to the winners of the #NobelPrize in Physics: John Clarke, Michel H. Devoret and John M. Martinis. Clarke and Martinis are both members of the Humboldt Network – as hosts for Feodor Lynen Research Fellows! 💚
Picture: Ill. Niklas Elmehed © Nobel Prize Outreach
Picture: Ill. Niklas Elmehed © Nobel Prize Outreach
October 7, 2025 at 10:26 AM
✨✨✨ Huge congratulations to the winners of the #NobelPrize in Physics: John Clarke, Michel H. Devoret and John M. Martinis. Clarke and Martinis are both members of the Humboldt Network – as hosts for Feodor Lynen Research Fellows! 💚
Picture: Ill. Niklas Elmehed © Nobel Prize Outreach
Picture: Ill. Niklas Elmehed © Nobel Prize Outreach
Reposted by Victor Puelles
In our paper @natimmunol.nature.com we highlight a spatiotemporally conserved progression program into glomerular crescents and sclerosis and indicate new treatment options for autoimmune kidney disease. #UKEHamburg #HCKH_Hamburg #HCTI @uni-hamburg.de www.nature.com/articles/s41...
Spatiotemporal interaction of immune and renal cells controls glomerular crescent formation in autoimmune kidney disease - Nature Immunology
Here the authors provide a deep tissue analysis of patients with autoimmune kidney diseases, identifying a conserved spatiotemporal immune program for the development of glomerular crescents and sclerosis.
www.nature.com
September 30, 2025 at 5:50 PM
In our paper @natimmunol.nature.com we highlight a spatiotemporally conserved progression program into glomerular crescents and sclerosis and indicate new treatment options for autoimmune kidney disease. #UKEHamburg #HCKH_Hamburg #HCTI @uni-hamburg.de www.nature.com/articles/s41...
Reposted by Victor Puelles
🚀 Excited to share scPortrait! Led by Sophia Mädler & Niklas Schmacke w/ the Mann lab — a new @scverse tool for standardized single-cell image data. Enables ML-ready extraction, >1B cell processing, cross-omics, & cancer macrophage insights.
🔗 www.biorxiv.org/content/10.1...
🔗 www.biorxiv.org/content/10.1...
September 28, 2025 at 5:50 PM
🚀 Excited to share scPortrait! Led by Sophia Mädler & Niklas Schmacke w/ the Mann lab — a new @scverse tool for standardized single-cell image data. Enables ML-ready extraction, >1B cell processing, cross-omics, & cancer macrophage insights.
🔗 www.biorxiv.org/content/10.1...
🔗 www.biorxiv.org/content/10.1...
Reposted by Victor Puelles
Check out our latest review on Basement Membranes!
Including scaled representation of protein & glycan components 😊
@mcrcellmatrix.bsky.social
Including scaled representation of protein & glycan components 😊
@mcrcellmatrix.bsky.social
In their Cell Science at a Glance article, Rachel Lennon @rachellennon.bsky.social and David Sherwood review basement membrane composition, formation and function, and discuss how BMs change in health and disease.
journals.biologists.com/jcs/article/...
#OpenAccess
journals.biologists.com/jcs/article/...
#OpenAccess
September 19, 2025 at 5:43 PM
Check out our latest review on Basement Membranes!
Including scaled representation of protein & glycan components 😊
@mcrcellmatrix.bsky.social
Including scaled representation of protein & glycan components 😊
@mcrcellmatrix.bsky.social
Reposted by Victor Puelles
🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
September 17, 2025 at 1:10 PM
🥁 Check out our new preprint on OmniPath, the prior knowledge resource for #SystemsBiology, and its brand-new OmniPath Explorer web app! 🥳
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
📖 Preprint: www.biorxiv.org/content/10.1...
🔍 Explorer: explore.omnipathdb.org
OmniPath integrates 160+ resources for multi-omics analysis & modeling.
🧶⬇️
Reposted by Victor Puelles
Today 20 years after I started working in a scientific lab while still in 🇨🇱, my lab, the @cellcommlab.bsky.social has its 5th labversary.
What a ride ! I'm thankful for the support of my family, friends, & so many great collabs & colleagues.
Fig legend 👇🏽 + pending longer thread #PIlife #Science
What a ride ! I'm thankful for the support of my family, friends, & so many great collabs & colleagues.
Fig legend 👇🏽 + pending longer thread #PIlife #Science
September 1, 2025 at 10:00 PM
Today 20 years after I started working in a scientific lab while still in 🇨🇱, my lab, the @cellcommlab.bsky.social has its 5th labversary.
What a ride ! I'm thankful for the support of my family, friends, & so many great collabs & colleagues.
Fig legend 👇🏽 + pending longer thread #PIlife #Science
What a ride ! I'm thankful for the support of my family, friends, & so many great collabs & colleagues.
Fig legend 👇🏽 + pending longer thread #PIlife #Science
Reposted by Victor Puelles
Definitely the most unexpected @mesospim.bsky.social #lightsheet #microscopy application of the past years: Hunting dark matter with a lightsheet microscope! #astronomy 🔭🔬https://arxiv.org/abs/2503.20732
💥How can light-sheet help reveal dark matter?💥
Join Prof. Laura Baudis @lbaudis.bsky.social at #mesoSPIM Symposium, Oct 13–15 in Zurich or online, to see how light-sheet fluorescence microscopy 🔬 is used to image nuclear ☢️ recoil tracks to detect elusive particles!
Register now: t.uzh.ch/1Ss
Join Prof. Laura Baudis @lbaudis.bsky.social at #mesoSPIM Symposium, Oct 13–15 in Zurich or online, to see how light-sheet fluorescence microscopy 🔬 is used to image nuclear ☢️ recoil tracks to detect elusive particles!
Register now: t.uzh.ch/1Ss
August 21, 2025 at 1:39 PM
Definitely the most unexpected @mesospim.bsky.social #lightsheet #microscopy application of the past years: Hunting dark matter with a lightsheet microscope! #astronomy 🔭🔬https://arxiv.org/abs/2503.20732
Reposted by Victor Puelles
Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social
August 7, 2025 at 6:12 PM
Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social
Reposted by Victor Puelles
Nature research paper: Pathology-oriented multiplexing enables integrative disease mapping
go.nature.com/3HdZxZG
go.nature.com/3HdZxZG
Pathology-oriented multiplexing enables integrative disease mapping - Nature
Pathology-oriented multiplexing (PathoPlex) represents a framework for widespread access to multiplexed imaging and computational image analysis of clinical specimens at a relatively high throughput and subcellular resolution.
go.nature.com
August 1, 2025 at 12:35 PM
Nature research paper: Pathology-oriented multiplexing enables integrative disease mapping
go.nature.com/3HdZxZG
go.nature.com/3HdZxZG
Reposted by Victor Puelles
Glad to contribute to this collaborative community platform.
A case study shows MCP servers working together - combining BioContextAI Knowledgebase with our omnipath omnipathdb.org MCP (work in progress) to showcase interoperability. Looking forward to see how the ecosystem evolves!
A case study shows MCP servers working together - combining BioContextAI Knowledgebase with our omnipath omnipathdb.org MCP (work in progress) to showcase interoperability. Looking forward to see how the ecosystem evolves!
Preprint alert 🚨 Do you use chatbots in your work or even build MCP servers and agentic systems yourself?
Or would you like to find a way to use biomedical tools using natural language?
Then check out biocontext.ai, now out on bioRxiv: www.biorxiv.org/content/10.1...
Or would you like to find a way to use biomedical tools using natural language?
Then check out biocontext.ai, now out on bioRxiv: www.biorxiv.org/content/10.1...
July 31, 2025 at 7:37 AM
Glad to contribute to this collaborative community platform.
A case study shows MCP servers working together - combining BioContextAI Knowledgebase with our omnipath omnipathdb.org MCP (work in progress) to showcase interoperability. Looking forward to see how the ecosystem evolves!
A case study shows MCP servers working together - combining BioContextAI Knowledgebase with our omnipath omnipathdb.org MCP (work in progress) to showcase interoperability. Looking forward to see how the ecosystem evolves!
Reposted by Victor Puelles
Preprint alert 🚨 Do you use chatbots in your work or even build MCP servers and agentic systems yourself?
Or would you like to find a way to use biomedical tools using natural language?
Then check out biocontext.ai, now out on bioRxiv: www.biorxiv.org/content/10.1...
Or would you like to find a way to use biomedical tools using natural language?
Then check out biocontext.ai, now out on bioRxiv: www.biorxiv.org/content/10.1...
July 29, 2025 at 12:41 PM
Preprint alert 🚨 Do you use chatbots in your work or even build MCP servers and agentic systems yourself?
Or would you like to find a way to use biomedical tools using natural language?
Then check out biocontext.ai, now out on bioRxiv: www.biorxiv.org/content/10.1...
Or would you like to find a way to use biomedical tools using natural language?
Then check out biocontext.ai, now out on bioRxiv: www.biorxiv.org/content/10.1...